CFinderADM000727's detailed annotation
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Protein: Yellow color--query protein Green color--interaction proteins. Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
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Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontolog |
|---|---|---|
| uracil degradation I (reductive) | 2.16E-05 | plantCyc |
| formation of glycosidic bonds, GlycosylTransferases: GTnc | 6.01E-05 | cazy family |
| euchromatin | 0.000103932 | GO:0000791 |
| post-translational protein modification | 0.000158622 | GO:0043687 |
| double-strand break repair | 0.000158622 | GO:0006302 |
| negative regulation of protein kinase activity | 0.000158622 | GO:0006469 |
| uracil catabolic process | 0.000158622 | GO:0006212 |
| meiotic cell cycle | 0.000158622 | GO:0051321 |
| Mre11 complex | 0.00017307 | GO:0030870 |
| protein kinase inhibitor activity | 0.000187507 | GO:0004860 |
| dihydropyrimidinase activity | 0.000187507 | GO:0004157 |
| signal recognition particle, endoplasmic reticulum targeting | 0.000207325 | GO:0005786 |
| synaptonemal complex | 0.000207325 | GO:0000795 |
| COPI vesicle coat | 0.000207325 | GO:0030126 |
| oligosaccharyltransferase complex | 0.000207325 | GO:0008250 |
| endoplasmic reticulum lumen | 0.000271262 | GO:0005788 |
| dolichyl-diphosphooligosaccharide-protein glycotransferase activity | 0.000436759 | GO:0004579 |
| double-stranded RNA binding | 0.000436759 | GO:0003725 |
| protein N-linked glycosylation via asparagine | 0.00048363 | GO:0018279 |
| SRP-dependent cotranslational protein targeting to membrane | 0.000587384 | GO:0006614 |
| 7S RNA binding | 0.000685443 | GO:0008312 |
| fatty-acyl-CoA binding | 0.000809368 | GO:0000062 |
| protein kinase binding | 0.001065912 | GO:0019901 |
| intra-Golgi vesicle-mediated transport | 0.001225737 | GO:0006891 |
| retrograde vesicle-mediated transport, Golgi to ER | 0.001225737 | GO:0006890 |
| structural molecule activity | 0.001327333 | GO:0005198 |
| 3'-5' exonuclease activity | 0.001900203 | GO:0008408 |
| endonuclease activity | 0.002012059 | GO:0004519 |
| manganese ion binding | 0.002125594 | GO:0030145 |
| ER to Golgi vesicle-mediated transport | 0.004063894 | GO:0006888 |
| N-Glycan biosynthesis | 0.006338833 | KEGG pathway |
| Protein export | 0.006338833 | KEGG pathway |
| Pyrimidine metabolism | 0.006338833 | KEGG pathway |
| response to stress | 0.007121258 | GO:0006950 |
| Homologous recombination | 0.007138884 | KEGG pathway |
| unfolded protein binding | 0.00723928 | GO:0051082 |
| nucleic acid phosphodiester bond hydrolysis | 0.007267905 | GO:0090305 |
| nucleolus | 0.016523775 | GO:0005730 |
| protein folding | 0.016536343 | GO:0006457 |
| intracellular protein transport | 0.017999138 | GO:0006886 |
| GTPase activity | 0.018944305 | GO:0003924 |
| Ubiquitin_Proteasome_system, E3 adaptor: DWD | 0.025151635 | ubs family |
| Golgi apparatus | 0.029267943 | GO:0005794 |
| endoplasmic reticulum | 0.029764698 | GO:0005783 |
| GTP binding | 0.039731378 | GO:0005525 |
Module member annotation
| Gene ID | Ortholog in Arabidopsis (Blast E-value) | Annotation in Arabidopsis |
|---|---|---|
| CRO_T002076 | AT1G35220 (8.00E-126) | unknown protein |
| CRO_T005817 | AT5G17510 (5.00E-77) | unknown protein |
| CRO_T011082 | AT1G35220 (1.00E-77) | unknown protein |
| CRO_T013367 | AT1G48900 (6.00E-126) | Signal recognition particle, SRP54 subunit protein |
| CRO_T016194 | AT5G54260 (0) | ATMRE11|ARABIDOPSIS MEIOTIC RECOMBINATION 11; MRE11|MEIOTIC RECOMBINATION 11 |
| CRO_T017383 | AT3G02700 (1.00E-82) | NC domain-containing protein-related |
| CRO_T021736 | AT1G52360 (5.00E-141) | Coatomer, beta' subunit |
| CRO_T022566 | AT5G52640 (2.00E-70) | AtHsp90-1|HEAT SHOCK PROTEIN 90-1; ATHSP90.1|heat shock protein 90.1; HSP81-1|HEAT SHOCK PROTEIN 81-1; HSP83|HEAT SHOCK PROTEIN 83 |
| CRO_T026026 | - | - |
| CRO_T028357 | AT2G15270 (1.00E-26) | unknown protein |
| CRO_T032526 | AT5G12200 (2.00E-16) | PYD2|pyrimidine 2 |
| CRO_T032634 | AT5G19690 (3.00E-62) | STT3A|staurosporin and temperature sensitive 3-like A |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| CFinderADM000002 | Transcription_related, Transcription factor: M-type phosphatidylethanolamine binding L-alanine biosynthesis III nickel cation binding photoperiodism, flowering molybdenum cofactor biosynthesis transferase activity, transferring alkyl or aryl (other than methyl) groups regulation of flower development nitrogen compound metabolic process Circadian rhythm - plant Transcription_related, Transcription factor: G2-like transferase activity, transferring hexosyl groups Transcription_related, Transcription factor: MYB-related DNA-directed RNA polymerase activity Terpenoid backbone biosynthesis Transcription_related, Transcription factor: B3 multicellular organism development Transcription_related, Transcription factor: NAC binding Transcription_related, Transcription factor: FAR1 transcription, DNA-templated GTPase activity Purine metabolism | details |
| CFinderADM000327 | GTPase activity GTP binding formation of glycosidic bonds, GlycosylTransferases: GTnc | details |
| CFinderADM000398 | Protein processing in endoplasmic reticulum unfolded protein binding endoplasmic reticulum lumen protein folding dolichyl-phosphate-mannose-protein mannosyltransferase complex endoplasmic reticulum chain elongation of O-linked mannose residue positive regulation by host of viral process pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response cell wall mannoprotein biosynthetic process regulation of endoplasmic reticulum unfolded protein response calcium ion binding dolichyl-phosphate-mannose-protein mannosyltransferase activity protein O-linked mannosylation defense response to fungus Protein export defense response to bacterium response to stress multicellular organism development 2-alkenal reductase [NAD(P)] activity carbohydrate binding ATP binding | details |
| CFinderADM000417 | formation of glycosidic bonds, GlycosylTransferases: GTnc oligosaccharyltransferase complex post-translational protein modification protein N-linked glycosylation via asparagine dolichyl-diphosphooligosaccharide-protein glycotransferase activity redox enzymes that act in conjunction with CAZymes, Auxiliary Activities: AA7 vindoline and vinblastine biosynthesis N-Glycan biosynthesis oxidoreductase activity, acting on CH-OH group of donors oxidation-reduction process flavin adenine dinucleotide binding dioxygenase activity transporter activity transport | details |
| CFinderADM000559 | ATP-dependent microtubule motor activity, plus-end-directed kinesin complex microtubule-based movement coenzyme binding microtubule binding catalytic activity | details |
| CFinderADM000764 | SRP-dependent cotranslational protein targeting to membrane tRNA aminoacylation for protein translation signal recognition particle, endoplasmic reticulum targeting aminoacyl-tRNA ligase activity 7S RNA binding Aminoacyl-tRNA biosynthesis Protein export GTPase activity ATPase activity, coupled to transmembrane movement of substances GTP binding transmembrane transport integral component of membrane | details |
| CFinderADM000932 | PcG protein complex negative regulation of molecular function, epigenetic organic acid catabolic process negative regulation of protein kinase activity regulation of gene expression by genetic imprinting organonitrogen compound catabolic process protein kinase inhibitor activity single-stranded RNA binding histone methylation DNA mediated transformation double-stranded RNA binding Valine, leucine and isoleucine degradation L-valine degradation I protein kinase binding leaf morphogenesis Lysine degradation vegetative to reproductive phase transition of meristem oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor nucleolus methyltransferase activity | details |
| CFinderADM001195 | hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc condensed chromosome kinetochore nuclear pore distribution transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery chromatin organization oligosaccharide metabolic process nuclear pore outer ring RNA export from nucleus beta-N-acetylhexosaminidase activity mannosyl-oligosaccharide glucosidase activity nucleocytoplasmic transporter activity protein N-linked glycosylation structural constituent of nuclear pore protein import into nucleus UDP-glucosyltransferase activity N-Glycan biosynthesis Amino sugar and nucleotide sugar metabolism GTPase activity RNA transport GTP binding endoplasmic reticulum membrane carbohydrate metabolic process | details |
| CFinderADM001248 | ELL-EAF complex signal recognition particle, endoplasmic reticulum targeting retromer complex U4/U6 x U5 tri-snRNP complex SRP-dependent cotranslational protein targeting to membrane vesicle docking involved in exocytosis retrograde transport, endosome to Golgi 7S RNA binding translational elongation formation of glycosidic bonds, GlycosylTransferases: GTnc mRNA splicing, via spliceosome translation elongation factor activity Protein export protein transporter activity Endocytosis endosome intracellular protein transport GTPase activity Spliceosome Golgi apparatus GTP binding transferase activity RNA binding | details |
| CFinderADM001391 | phenylalanine-tRNA ligase complex Transcription_related, Transcription regulator: ARID phenylalanyl-tRNA aminoacylation karyogamy signal recognition particle, endoplasmic reticulum targeting SRP-dependent cotranslational protein targeting to membrane fatty-acyl-CoA binding 7S RNA binding phenylalanine-tRNA ligase activity Aminoacyl-tRNA biosynthesis Protein export GTPase activity magnesium ion binding GTP binding RNA binding cytosol | details |
| CFinderADM001552 | Transcription_related, Transcription factor: BES1 brassinosteroid mediated signaling pathway Plant hormone signal transduction transcription, DNA-templated transferase activity transcription factor activity, sequence-specific DNA binding | details |
| CFinderADM001737 | negative regulation of protein kinase activity protein kinase inhibitor activity double-stranded RNA binding solute:proton antiporter activity protein kinase binding Insulin signaling pathway exocyst exocytosis hydrogen ion transmembrane transport nucleolus | details |
| CFinderADM001743 | Aminoacyl-tRNA biosynthesis mitochondrial alanyl-tRNA aminoacylation tRNA aminoacylation for protein translation SRP-dependent cotranslational protein targeting to membrane alanine-tRNA ligase activity aminoacyl-tRNA ligase activity 7S RNA binding tRNA binding tRNA modification signal recognition particle, endoplasmic reticulum targeting Protein export amino acid binding GTPase activity GTP binding catalytic activity vacuolar membrane endoplasmic reticulum Golgi apparatus | details |
| CFinderADM001787 | Aminoacyl-tRNA biosynthesis mitochondrial alanyl-tRNA aminoacylation proteasome storage granule regulation of protein catabolic process enzyme regulator activity endopeptidase activity alanine-tRNA ligase activity tRNA aminoacylation for protein translation SRP-dependent cotranslational protein targeting to membrane 7S RNA binding aminoacyl-tRNA ligase activity signal recognition particle, endoplasmic reticulum targeting tRNA binding proteasome regulatory particle, base subcomplex tRNA modification Proteasome Protein export regulation of catalytic activity amino acid binding proteasome-mediated ubiquitin-dependent protein catabolic process GTPase activity GTP binding | details |
| CFinderADM001788 | transferase activity, transferring pentosyl groups mitochondrial proton-transporting ATP synthase complex assembly L-glutamine degradation I L-histidine biosynthesis fatty-acyl-CoA binding glycerol channel activity water channel activity cellular water homeostasis water transport glycerol transport cellular amino acid biosynthetic process ion transmembrane transport protein polyubiquitination protein ubiquitination involved in ubiquitin-dependent protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process Biosynthesis of amino acids ubiquitin protein ligase activity Ubiquitin_Proteasome_system, E3: U-box vacuole integral component of plasma membrane plasmodesma Ubiquitin_Proteasome_system, E3: RING | details |
| CFinderADM002034 | formation of glycosidic bonds, GlycosylTransferases: GTnc stem cell fate determination Golgi vesicle docking Golgi to plasma membrane protein transport meristem maintenance cellular calcium ion homeostasis post-translational protein modification Golgi stack pollen maturation oligosaccharyltransferase complex oxidoreductase activity, acting on the CH-CH group of donors cation-transporting ATPase activity dolichyl-diphosphooligosaccharide-protein glycotransferase activity protein N-linked glycosylation via asparagine cellular response to phosphate starvation pollen germination cation transmembrane transport intra-Golgi vesicle-mediated transport Autophagy - yeast N-Glycan biosynthesis protein polyubiquitination very long chain fatty acid biosynthesis I very long chain fatty acid biosynthesis II protein ubiquitination involved in ubiquitin-dependent protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process ATPase activity lipid metabolic process Ubiquitin_Proteasome_system, E3: U-box ubiquitin protein ligase activity endoplasmic reticulum integral component of plasma membrane Ubiquitin_Proteasome_system, E3: RING nucleotide binding | details |
| CFinderADM002039 | transferase activity, transferring pentosyl groups phenylalanyl-tRNA aminoacylation Transcription_related, Transcription factor: NF-YB phenylalanine-tRNA ligase complex RNA binding phenylalanine-tRNA ligase activity L-glutamine degradation I L-histidine biosynthesis fatty-acyl-CoA binding cellular amino acid biosynthetic process Aminoacyl-tRNA biosynthesis Biosynthesis of amino acids protein heterodimerization activity ATP-dependent RNA helicase activity magnesium ion binding nucleus ATP binding | details |
| CFinderADM002266 | regulation of production of siRNA involved in chromatin silencing by small RNA DNA-directed RNA polymerase V complex mismatch repair complex RNA-directed DNA methylation Mismatch repair mismatched DNA binding protein homodimerization activity | details |
Expression profiles
 Show details about module gene expression profiling |