CFinderADM001164's detailed annotation
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Protein: Yellow color--query protein Green color--interaction proteins. Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
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Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontolog |
|---|---|---|
| pyruvate dehydrogenase complex | 3.47E-06 | GO:0045254 |
| isocitrate dehydrogenase (NAD+) activity | 6.90E-06 | GO:0004449 |
| dihydrolipoyllysine-residue acetyltransferase activity | 6.90E-06 | GO:0004742 |
| pyruvate metabolic process | 8.54E-06 | GO:0006090 |
| ncRNA processing | 8.54E-06 | GO:0034470 |
| Carbon metabolism | 1.25E-05 | KEGG pathway |
| regulation of photomorphogenesis | 1.59E-05 | GO:0010099 |
| L-glutamine biosynthesis III | 0.000115123 | plantCyc |
| pyruvate decarboxylation to acetyl CoA | 0.000115123 | plantCyc |
| TCA cycle II (plants and fungi) | 0.000115123 | plantCyc |
| Ubiquitin_Proteasome_system, E2: UBC | 0.000201747 | ubs family |
| tricarboxylic acid cycle | 0.000210914 | GO:0006099 |
| mitochondrial matrix | 0.00044792 | GO:0005759 |
| NAD binding | 0.001679393 | GO:0051287 |
| magnesium ion binding | 0.001854826 | GO:0000287 |
| ligase activity | 0.001854826 | GO:0016874 |
| Ubiquitin mediated proteolysis | 0.002488798 | KEGG pathway |
| RNA transport | 0.003322403 | KEGG pathway |
Module member annotation
| Gene ID | Ortholog in Arabidopsis (Blast E-value) | Annotation in Arabidopsis |
|---|---|---|
| CRO_T007389 | AT1G32480 (2.00E-68) | IDH-IV|isocitrate dehydrogenase IV |
| CRO_T012408 | AT1G36340 (2.00E-27) | UBC31|ubiquitin-conjugating enzyme 31 |
| CRO_T016754 | AT2G24420 (2.00E-80) | DNA repair ATPase-related |
| CRO_T021091 | AT1G54220 (7.00E-177) | Dihydrolipoamide acetyltransferase, long form protein |
| CRO_T033552 | AT2G47300 (6.00E-88) | POP1|similar to yeast POP1 |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| CFinderADM000002 | Transcription_related, Transcription factor: M-type phosphatidylethanolamine binding L-alanine biosynthesis III nickel cation binding photoperiodism, flowering molybdenum cofactor biosynthesis transferase activity, transferring alkyl or aryl (other than methyl) groups regulation of flower development nitrogen compound metabolic process Circadian rhythm - plant Transcription_related, Transcription factor: G2-like transferase activity, transferring hexosyl groups Transcription_related, Transcription factor: MYB-related DNA-directed RNA polymerase activity Terpenoid backbone biosynthesis Transcription_related, Transcription factor: B3 multicellular organism development Transcription_related, Transcription factor: NAC binding Transcription_related, Transcription factor: FAR1 transcription, DNA-templated GTPase activity Purine metabolism | details |
| CFinderADM001163 | Protein_kinases_phosphatases, PPC:4.5.3: Casein Kinase II Family isocitrate dehydrogenase (NAD+) activity histidinol-phosphate transaminase activity ncRNA processing regulation of photomorphogenesis histidine biosynthetic process L-glutamine biosynthesis III TCA cycle II (plants and fungi) L-phenylalanine:2-oxoglutarate aminotransferase activity Ubiquitin_Proteasome_system, E2: UBC tricarboxylic acid cycle NAD binding Biosynthesis of amino acids Ribosome biogenesis in eukaryotes Ubiquitin mediated proteolysis pyridoxal phosphate binding magnesium ion binding ligase activity RNA transport Carbon metabolism protein phosphorylation protein serine/threonine kinase activity | details |
| CFinderADM001264 | pyruvate dehydrogenase complex pyruvate metabolic process secondary metabolic process 4-aminobutanoate degradation I 4-aminobutanoate degradation IV ternatin C3 biosynthesis dihydrolipoyllysine-residue acetyltransferase activity L-glutamate degradation IV pyruvate decarboxylation to acetyl CoA mitochondrial respiratory chain complex I Butanoate metabolism ATP synthesis coupled electron transport NAD/NADH phosphorylation and dephosphorylation mitochondrial matrix aerobic respiration III (alternative oxidase pathway) aerobic respiration I (cytochrome c) transaminase activity serine-type carboxypeptidase activity 2 iron, 2 sulfur cluster binding identical protein binding 4 iron, 4 sulfur cluster binding proteolysis involved in cellular protein catabolic process transferase activity, transferring acyl groups other than amino-acyl groups NADH dehydrogenase (ubiquinone) activity response to oxidative stress electron carrier activity pyridoxal phosphate binding Carbon metabolism Oxidative phosphorylation chloroplast | details |
| CFinderADM001314 | Carbon metabolism glycolytic process glycolysis IV (plant cytosol) glycolysis I (from glucose 6-phosphate) magnesium ion binding mitochondrial respiratory chain complex III isocitrate dehydrogenase (NAD+) activity fructose-bisphosphate aldolase activity mitochondrial electron transport, ubiquinol to cytochrome c pyruvate kinase activity potassium ion binding aerobic respiration protein processing tricarboxylic acid cycle L-glutamine biosynthesis III TCA cycle II (plants and fungi) sucrose biosynthesis I (from photosynthesis) Calvin-Benson-Bassham cycle Rubisco shunt aerobic respiration I (cytochrome c) gluconeogenesis I metalloendopeptidase activity NAD binding kinase activity hydrolase activity cytoplasm | details |
| CFinderADM001434 | glutathione-glutaredoxin redox reactions glutathione-disulfide reductase activity glutathione-peroxide redox reactions Carbon metabolism Glutathione metabolism NADP binding glutathione metabolic process cell redox homeostasis cellular oxidant detoxification flavin adenine dinucleotide binding dihydrolipoyllysine-residue acetyltransferase activity pyruvate dehydrogenase complex pyruvate metabolic process oxoglutarate dehydrogenase (succinyl-transferring) activity mannokinase activity glucokinase activity glucose binding 2-oxoglutarate decarboxylation to succinyl-CoA glucose 6-phosphate metabolic process cellular glucose homeostasis pyruvate decarboxylation to acetyl CoA thiamine pyrophosphate binding fructokinase activity carbohydrate phosphorylation tricarboxylic acid cycle glycolytic process mitochondrial matrix Peroxisome oxidation-reduction process cytosol chloroplast | details |
| CFinderADM001503 | Carbon metabolism mitochondrial matrix tricarboxylic acid cycle pyruvate dehydrogenase complex oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase activity citrate (Si)-synthase activity dihydrolipoyllysine-residue acetyltransferase activity citrate metabolic process pyruvate metabolic process glutathione-disulfide reductase activity glucose 6-phosphate metabolic process glucokinase activity glucose binding mannokinase activity cellular glucose homeostasis 4-aminobutanoate degradation I 4-aminobutanoate degradation IV glutathione-glutaredoxin redox reactions Butanoate metabolism 2-oxoglutarate decarboxylation to succinyl-CoA fructokinase activity glutathione-peroxide redox reactions L-glutamate degradation IV pyruvate decarboxylation to acetyl CoA glyoxylate cycle L-glutamine biosynthesis III TCA cycle II (plants and fungi) transaminase activity carbohydrate phosphorylation Glutathione metabolism glycolytic process glutathione metabolic process identical protein binding NADP binding cell redox homeostasis cellular oxidant detoxification flavin adenine dinucleotide binding pyridoxal phosphate binding Ubiquitin_Proteasome_system, E3 adaptor: F-box | details |
| CFinderADM001918 | intracellular protein transport Protein_kinases_phosphatases, PPC:5.1.1: Other Kinase membrane fusion regulation of photomorphogenesis soluble NSF attachment protein activity syntaxin binding COPI vesicle coat Ubiquitin_Proteasome_system, E2: UBC ATP synthesis coupled electron transport mitochondrial respiratory chain complex I structural molecule activity aerobic respiration I (cytochrome c) aerobic respiration III (alternative oxidase pathway) NAD/NADH phosphorylation and dephosphorylation 2 iron, 2 sulfur cluster binding SNARE complex 4 iron, 4 sulfur cluster binding vesicle-mediated transport Golgi membrane response to oxidative stress NADH dehydrogenase (ubiquinone) activity Ubiquitin mediated proteolysis electron carrier activity ligase activity vacuolar membrane Oxidative phosphorylation | details |
Expression profiles
 Show details about module gene expression profiling |