TissueCFM000315's detailed annotation
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Protein: Yellow color--query protein Green color--interaction proteins. Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
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Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontolog |
|---|---|---|
| formation of glycosidic bonds, GlycosylTransferases: GTnc | 0.003190782 | cazy family |
| positive regulation of translational initiation | 0.00347492 | GO:0045948 |
| recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex | 0.00347492 | GO:0034402 |
| mRNA export from nucleus in response to heat stress | 0.00347492 | GO:0031990 |
| transcription initiation from RNA polymerase II promoter | 0.006512588 | GO:0006367 |
| nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | 0.00677159 | GO:0000288 |
| Phenylpropanoid biosynthesis | 0.011998977 | KEGG pathway |
| geraniol dehydrogenase activity | 0.012981097 | GO:0047924 |
| single-stranded RNA binding | 0.012981097 | GO:0003727 |
| cinnamyl-alcohol dehydrogenase activity | 0.013492362 | GO:0045551 |
| sinapyl alcohol dehydrogenase activity | 0.013492362 | GO:0052747 |
| translation initiation factor binding | 0.013492362 | GO:0031369 |
| Transcription_related, Transcription factor: C3H | 0.013515812 | TF family |
| cytoplasmic mRNA processing body | 0.014150788 | GO:0000932 |
| mitochondrial respiratory chain complex I | 0.014150788 | GO:0005747 |
| DNA-directed RNA polymerase II, core complex | 0.014150788 | GO:0005665 |
| single-stranded DNA binding | 0.019015042 | GO:0003697 |
| DNA-directed RNA polymerase activity | 0.034018533 | GO:0003899 |
| Purine metabolism | 0.039983053 | KEGG pathway |
Module member annotation
| Gene ID | Ortholog in Arabidopsis (Blast E-value) | Annotation in Arabidopsis |
|---|---|---|
| CRO_T009342 | AT2G41640 (1.00E-72) | Glycosyltransferase family 61 protein |
| CRO_T010030 | AT5G09920 (2.00E-69) | ATRPB15.9; NRPB4; RPB15.9; RPB15.9.9|RNA polymerase II, Rpb4, core protein |
| CRO_T011790 | AT5G47570 (2.00E-43) | unknown protein |
| CRO_T019494 | AT4G37990 (5.00E-123) | ATCAD8|CINNAMYL-ALCOHOL DEHYDROGENASE 8; CAD-B2|CINNAMYL-ALCOHOL DEHYDROGENASE B2; ELI3|ELICITOR-ACTIVATED GENE 3; ELI3-2|elicitor-activated gene 3-2 |
| CRO_T029205 | AT3G04960 (5.00E-23) | Domain of unknown function (DUF3444) |
| CRO_T031532 | AT3G26850 (6.00E-10) | histone-lysine N-methyltransferases |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TissueCFM000007 | details | |
| TissueCFM000237 | Glycolysis / Gluconeogenesis aldose 1-epimerase activity postreplication repair hexose metabolic process positive regulation of catalytic activity double-strand break repair via homologous recombination protein processing Smc5-Smc6 complex mitochondrial respiratory chain complex I drug transmembrane transport | details |
| TissueCFM000238 | flavonoid 3',5'-hydroxylase activity phosphopantetheine binding primary shoot apical meristem specification anthocyanin-containing compound biosynthetic process oxidoreductase activity, acting on NAD(P)H FK506 binding aerobic respiration I (cytochrome c) aerobic respiration III (alternative oxidase pathway) flavonoid biosynthesis (in equisetum) flavonol biosynthesis leucodelphinidin biosynthesis leucopelargonidin and leucocyanidin biosynthesis NAD/NADH phosphorylation and dephosphorylation syringetin biosynthesis electron transport chain chaperone-mediated protein folding protein peptidyl-prolyl isomerization peptidyl-prolyl cis-trans isomerase activity Ubiquitin_Proteasome_system, E3 adaptor: DWD Oxidative phosphorylation protein binding | details |
| TissueCFM000346 | secondary shoot formation meristem initiation formation of glycosidic bonds, GlycosylTransferases: GTnc Transcription_related, Transcription factor: GRAS | details |
| TissueCFM000347 | formation of glycosidic bonds, GlycosylTransferases: GTnc organic cyclic compound binding heterocyclic compound binding | details |
| TissueCFM000654 | DNA replication factor C complex DNA clamp loader activity Transcription_related, Transcription factor: C3H DNA-dependent DNA replication cellular macromolecule biosynthetic process DNA metabolic process DNA replication Purine metabolism | details |
| TissueCFM000720 | Protein_kinases_phosphatases, PPC:1.1.1: Leucine-rich transmembrane protein kinase/Strubbelig Receptor Family 1 anthocyanin-containing compound biosynthetic process flavonoid 3',5'-hydroxylase activity electron transport chain oxidoreductase activity, acting on NAD(P)H hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc aerobic respiration I (cytochrome c) aerobic respiration III (alternative oxidase pathway) flavonoid biosynthesis (in equisetum) flavonol biosynthesis leucodelphinidin biosynthesis leucopelargonidin and leucocyanidin biosynthesis NAD/NADH phosphorylation and dephosphorylation syringetin biosynthesis Oxidative phosphorylation | details |
| TissueCFM001021 | MutLalpha complex chiasma Transcription_related, Transcription factor: Whirly synaptonemal complex nuclear body anaphase-promoting complex L-valine degradation I nuclear chromatin anaphase-promoting complex-dependent catabolic process regulation of mitotic metaphase/anaphase transition negative regulation of DNA endoreduplication protein K11-linked ubiquitination cell proliferation mitotic recombination Mismatch repair phloem or xylem histogenesis seed development mitotic nuclear division seed germination mismatched DNA binding cell division pollen development Transcription_related, Transcription factor: C3H single-stranded DNA binding | details |
| TissueCFM001114 | Oxidative phosphorylation mitochondrial envelope mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) mitochondrial respiratory chain complex I hydrogen ion transmembrane transporter activity carboxylic ester hydrolase activity cytochrome-c oxidase activity aerobic respiration I (cytochrome c) aerobic respiration III (alternative oxidase pathway) NAD/NADH phosphorylation and dephosphorylation benzoate biosynthesis I (CoA-dependent, β-oxidative) NADH dehydrogenase (ubiquinone) activity | details |
| TissueCFM001118 | Transcription_related, Transcription regulator: Jumonji mRNA export from nucleus in response to heat stress positive regulation of translational initiation recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex positive regulation of catalytic activity transcription initiation from RNA polymerase II promoter nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay Phenylpropanoid biosynthesis protein processing cytoplasmic mRNA processing body DNA-directed RNA polymerase II, core complex intracellular ribonucleoprotein complex viral nucleocapsid geraniol dehydrogenase activity single-stranded RNA binding translation initiation factor binding cinnamyl-alcohol dehydrogenase activity sinapyl alcohol dehydrogenase activity single-stranded DNA binding DNA-directed RNA polymerase activity helicase activity | details |
| TissueCFM001428 | Transcription_related, Transcription regulator: Jumonji recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex positive regulation of translational initiation mRNA export from nucleus in response to heat stress transcription initiation from RNA polymerase II promoter nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay Phenylpropanoid biosynthesis cytosolic ribosome proteasome core complex DNA-directed RNA polymerase II, core complex single-stranded RNA binding geraniol dehydrogenase activity cytoplasmic mRNA processing body cinnamyl-alcohol dehydrogenase activity translation initiation factor binding sinapyl alcohol dehydrogenase activity intracellular ribonucleoprotein complex viral nucleocapsid single-stranded DNA binding threonine-type endopeptidase activity proteolysis involved in cellular protein catabolic process DNA-directed RNA polymerase activity helicase activity | details |
Expression profiles
 Show details about module gene expression profiling |