TissueCFM001309's detailed annotation
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Protein: Yellow color--query protein Green color--interaction proteins. Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
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Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontolog |
|---|---|---|
| pre-mRNA cleavage required for polyadenylation | 0.002600434 | GO:0098789 |
| L-phenylalanine biosynthetic process | 0.003899038 | GO:0009094 |
| L-phenylalanine biosynthesis II | 0.004250857 | plantCyc |
| L-phenylalanine biosynthesis III (cytosolic, plants) | 0.004250857 | plantCyc |
| mRNA cleavage and polyadenylation specificity factor complex | 0.007878474 | GO:0005847 |
| arogenate dehydratase activity | 0.012846211 | GO:0047769 |
| prephenate dehydratase activity | 0.012846211 | GO:0004664 |
| DNA metabolic process | 0.014256608 | GO:0006259 |
| Transcription_related, Transcription factor: HB | 0.017596921 | TF family |
| nucleotide binding | 0.020339093 | GO:0000166 |
| ATP-dependent helicase activity | 0.020339093 | GO:0008026 |
| mRNA binding | 0.029729326 | GO:0003729 |
| amino acid binding | 0.034132797 | GO:0016597 |
| Aminoacyl-tRNA biosynthesis | 0.040354519 | KEGG pathway |
| Biosynthesis of amino acids | 0.040354519 | KEGG pathway |
| mRNA surveillance pathway | 0.040354519 | KEGG pathway |
Module member annotation
| Gene ID | Ortholog in Arabidopsis (Blast E-value) | Annotation in Arabidopsis |
|---|---|---|
| CRO_T011567 | AT5G50350 (1.00E-06) | unknown protein |
| CRO_T012273 | AT5G38830 (8.00E-19) | Cysteinyl-tRNA synthetase, class Ia family protein |
| CRO_T013058 | AT1G60930 (2.00E-18) | ATRECQ4B|RECQ helicase L4B |
| CRO_T013526 | AT1G73360 (4.00E-130) | ATHDG11|HOMEODOMAIN GLABROUS 11; EDT1|ENHANCED DROUGHT TOLERANCE 1 |
| CRO_T015219 | AT4G32160 (4.00E-54) | Phox (PX) domain-containing protein |
| CRO_T021346 | AT5G33320 (8.00E-102) | ARAPPT|PHOSPHATE/PHOSPHOENOLPYRUVATE TRANSLOCATOR; CUE1|CAB UNDEREXPRESSED 1; PPT|PHOSPHOENOLPYRUVATE/PHOSPHATE TRANSLOCATOR |
| CRO_T028864 | AT1G08250 (1.00E-112) | ADT6|arogenate dehydratase 6 |
| CRO_T031348 | AT4G13850 (2.00E-10) | ATGRP2|GLYCINE-RICH RNA-BINDING PROTEIN 2; GRP2|glycine rich protein 2 |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TissueCFM000632 | pre-mRNA cleavage required for polyadenylation positive regulation of phosphorylation of RNA polymerase II C-terminal domain positive regulation of cyclin-dependent protein serine/threonine kinase activity Transcriptional misregulation in cancers positive regulation of transcription from RNA polymerase II promoter nucleotide binding cyclin-dependent protein serine/threonine kinase regulator activity cyclin-dependent protein kinase holoenzyme complex mRNA cleavage and polyadenylation specificity factor complex mRNA binding Protein_kinases_phosphatases, PPC:1.9.2: S Domain Kinase (Type 2) mRNA surveillance pathway | details |
| TissueCFM000696 | pre-mRNA cleavage required for polyadenylation L-valine degradation I Valine, leucine and isoleucine degradation mRNA cleavage and polyadenylation specificity factor complex single-organism metabolic process mRNA surveillance pathway mRNA binding | details |
| TissueCFM000925 | catalytic step 1 spliceosome prespliceosome Prp19 complex cyclin-dependent protein kinase holoenzyme complex post-mRNA release spliceosomal complex Golgi vesicle transport positive regulation of cyclin-dependent protein serine/threonine kinase activity positive regulation of phosphorylation of RNA polymerase II C-terminal domain positive regulation of transcription from RNA polymerase II promoter cytoplasmic microtubule organization spliceosomal complex assembly vesicle docking precatalytic spliceosome cyclin-dependent protein serine/threonine kinase regulator activity oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor | details |
| TissueCFM000926 | cytoplasmic microtubule organization oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor Aminoacyl-tRNA biosynthesis MAPK signaling pathway - plant microtubule-severing ATPase activity cytoplasmic part cellular oxidant detoxification | details |
| TissueCFM001022 | pre-mRNA cleavage required for polyadenylation positive regulation of phosphorylation of RNA polymerase II C-terminal domain positive regulation of cyclin-dependent protein serine/threonine kinase activity Transcriptional misregulation in cancers positive regulation of transcription from RNA polymerase II promoter cyclin-dependent protein kinase holoenzyme complex mRNA cleavage and polyadenylation specificity factor complex cyclin-dependent protein serine/threonine kinase regulator activity serine-type carboxypeptidase activity mRNA binding mRNA surveillance pathway proteolysis involved in cellular protein catabolic process | details |
| TissueCFM001200 | Protein_kinases_phosphatases, PPC:1.17.1: Wall Associated Kinase biotin biosynthesis from 8-amino-7-oxononanoate I protein retention in ER lumen ER retention sequence binding DNA metabolic process ATP-dependent helicase activity | details |
| TissueCFM001624 | cytoplasmic translation Transcriptional misregulation in cancers | details |
| TissueCFM001631 | nucleosome regulation of endosperm development THO complex MCM complex chromatin silencing DNA replication initiation DNA duplex unwinding nucleosome assembly nuclear chromatin DNA replication origin binding Basal transcription factors DNA replication Necroptosis DNA helicase activity Aminoacyl-tRNA biosynthesis | details |
| TissueCFM001777 | pre-mRNA cleavage required for polyadenylation mRNA cleavage and polyadenylation specificity factor complex mRNA surveillance pathway mRNA binding | details |
Expression profiles
 Show details about module gene expression profiling |