TreatCFM000987's detailed annotation
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Protein: Yellow color--query protein Green color--interaction proteins. Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
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Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontolog |
|---|---|---|
| Taurine and hypotaurine metabolism | 0.003722194 | KEGG pathway |
| spindle pole body duplication | 0.004581116 | GO:0030474 |
| establishment of spindle pole body localization to nuclear envelope | 0.004581116 | GO:0071790 |
| flavin-containing compound metabolic process | 0.004581116 | GO:0042726 |
| nuclear pore transmembrane ring | 0.004723347 | GO:0070762 |
| detection of hypoxia | 0.005724871 | GO:0070483 |
| positive regulation of ubiquitin-protein transferase activity | 0.005724871 | GO:0051443 |
| peptidyl-cysteine oxidation | 0.005724871 | GO:0018171 |
| anaerobic respiration | 0.005887917 | GO:0009061 |
| nuclear pore organization | 0.006010049 | GO:0006999 |
| pseudouridine synthesis | 0.006180669 | GO:0001522 |
| protein neddylation | 0.006180669 | GO:0045116 |
| FAD diphosphatase activity | 0.010095513 | GO:0047884 |
| cullin family protein binding | 0.010095513 | GO:0097602 |
| ubiquitin-like protein binding | 0.010095513 | GO:0032182 |
| structural constituent of nuclear pore | 0.014694962 | GO:0017056 |
| pseudouridine synthase activity | 0.014694962 | GO:0009982 |
| oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen | 0.014694962 | GO:0016702 |
| ubiquitin conjugating enzyme binding | 0.014694962 | GO:0031624 |
| phosphatidylcholine acyl editing | 0.017377439 | plantCyc |
| phospholipases | 0.017377439 | plantCyc |
| phospholipid remodeling (phosphatidylcholine, yeast) | 0.017377439 | plantCyc |
| ubiquitin ligase complex | 0.022402106 | GO:0000151 |
| ATPase activity | 0.044459322 | GO:0016887 |
| Purine metabolism | 0.046541824 | KEGG pathway |
| formation of glycosidic bonds, GlycosylTransferases: GTnc | 0.049602139 | cazy family |
Module member annotation
| Gene ID | Ortholog in Arabidopsis (Blast E-value) | Annotation in Arabidopsis |
|---|---|---|
| CRO_T001914 | AT2G42070 (8.00E-88) | ATNUDT23|NUDIX HYDROLASE HOMOLOG 23 |
| CRO_T006508 | AT1G63400 (3.00E-29) | Pentatricopeptide repeat (PPR) superfamily protein |
| CRO_T007233 | - | - |
| CRO_T008474 | AT1G18490 (3.00E-81) | Protein of unknown function (DUF1637) |
| CRO_T016648 | AT1G78910 (2.00E-158) | Pseudouridine synthase family protein |
| CRO_T030475 | AT1G15860 (6.00E-89) | Domain of unknown function (DUF298) |
| CRO_T030843 | AT4G29070 (1.00E-58) | Phospholipase A2 family protein |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TreatCFM000486 | nuclear pore transmembrane ring establishment of spindle pole body localization to nuclear envelope spindle pole body duplication PSII associated light-harvesting complex II catabolic process nuclear pore organization photoinhibition regulation of apoptotic process pseudouridine synthesis thylakoid membrane organization photosystem II repair sulfiredoxin activity nucleotide binding pseudouridine synthase activity structural constituent of nuclear pore ATP-dependent peptidase activity metalloendopeptidase activity formation of glycosidic bonds, GlycosylTransferases: GTnc ATPase activity | details |
| TreatCFM000664 | TFIIK complex Herpes simplex infection Selenocompound metabolism response to abiotic stimulus positive regulation of phosphorylation of RNA polymerase II C-terminal domain aspartyl-tRNA aminoacylation selenium compound metabolic process positive regulation of cyclin-dependent protein serine/threonine kinase activity positive regulation of ubiquitin-protein transferase activity protein neddylation S-adenosylmethionine metabolic process GDP-mannose transmembrane transport GDP-mannose transmembrane transporter activity cullin family protein binding aspartate-tRNA ligase activity ubiquitin-like protein binding vacuolar transport cyclin-dependent protein serine/threonine kinase regulator activity positive regulation of transcription from RNA polymerase II promoter cyclin-dependent protein kinase holoenzyme complex ubiquitin conjugating enzyme binding transaminase activity ubiquitin ligase complex | details |
| TreatCFM000842 | ferric iron binding ferroxidase activity FAD diphosphatase activity anaerobic respiration flavin-containing compound metabolic process peptidyl-cysteine oxidation detection of hypoxia MAPK signaling pathway - fly Taurine and hypotaurine metabolism oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen response to hydrogen peroxide aerobic respiration iron-sulfur cluster assembly Porphyrin and chlorophyll metabolism Ubiquitin_Proteasome_system, E3 adaptor: DWD | details |
| TreatCFM000948 | iron-sulfur cluster assembly formation of glycosidic bonds, GlycosylTransferases: GTnc nuclear pore transmembrane ring TFIIK complex protein N-glycosylation (eukaryotic, high mannose) flavin-containing compound metabolic process spindle pole body duplication establishment of spindle pole body localization to nuclear envelope FAD diphosphatase activity dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity oligosaccharide-lipid intermediate biosynthetic process ferric iron binding ferroxidase activity cyclin-dependent protein kinase holoenzyme complex positive regulation of phosphorylation of RNA polymerase II C-terminal domain nuclear pore organization positive regulation of cyclin-dependent protein serine/threonine kinase activity response to abiotic stimulus pseudouridine synthesis response to hydrogen peroxide cyclin-dependent protein serine/threonine kinase regulator activity protein N-linked glycosylation structural constituent of nuclear pore positive regulation of transcription from RNA polymerase II promoter pseudouridine synthase activity aerobic respiration iron-sulfur cluster binding Basal transcription factors N-Glycan biosynthesis Porphyrin and chlorophyll metabolism | details |
| TreatCFM001270 | Glycosaminoglycan degradation hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc Cytochrome_P450, Cytochrome P450: CYP81D sesamin biosynthesis defense response to other organism indole glucosinolate metabolic process secondary metabolite biosynthetic process membrane | details |
| TreatCFM001362 | TFIIK complex cyclin-dependent protein kinase holoenzyme complex response to abiotic stimulus spindle organization positive regulation of cyclin-dependent protein serine/threonine kinase activity G1/S transition of mitotic cell cycle positive regulation of phosphorylation of RNA polymerase II C-terminal domain positive regulation of mitotic centrosome separation RNA export from nucleus Basal transcription factors Viral carcinogenesis cyclin-dependent protein serine/threonine kinase regulator activity positive regulation of transcription from RNA polymerase II promoter Ran GTPase binding GTPase activator activity protein import into nucleus positive regulation of GTPase activity ubiquitin-dependent protein catabolic process formation of glycosidic bonds, GlycosylTransferases: GTnc | details |
| TreatCFM001407 | iron-sulfur cluster assembly TFIIK complex cullin family protein binding FAD diphosphatase activity ubiquitin-like protein binding ferroxidase activity ferric iron binding cyclin-dependent protein serine/threonine kinase regulator activity flavin-containing compound metabolic process detection of hypoxia peptidyl-cysteine oxidation positive regulation of ubiquitin-protein transferase activity positive regulation of phosphorylation of RNA polymerase II C-terminal domain anaerobic respiration positive regulation of cyclin-dependent protein serine/threonine kinase activity cyclin-dependent protein kinase holoenzyme complex response to abiotic stimulus protein neddylation response to hydrogen peroxide Taurine and hypotaurine metabolism positive regulation of transcription from RNA polymerase II promoter oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ubiquitin conjugating enzyme binding aerobic respiration ubiquitin ligase complex iron-sulfur cluster binding Basal transcription factors Porphyrin and chlorophyll metabolism | details |
| TreatCFM001482 | Transcription_related, Transcription factor: Alfin-like mevalonate pathway I pyridoxal 5'-phosphate salvage I FAD diphosphatase activity pyridoxal kinase activity mevalonate kinase activity flavin-containing compound metabolic process peptidyl-cysteine oxidation anaerobic respiration pyridoxal 5'-phosphate salvage detection of hypoxia Taurine and hypotaurine metabolism Vitamin B6 metabolism phosphorylation zinc ion binding isoprenoid biosynthetic process | details |
| TreatCFM001607 | mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity [ribulose-bisphosphate carboxylase]-lysine N-methyltransferase activity sulfiredoxin activity nuclear speck MIS complex protein-lysine N-methyltransferase activity single-organism transport gametophyte development mRNA methylation peptidyl-lysine monomethylation chloroplast part chloroplast membrane part thylakoid cellular protein metabolic process protein transport single-organism cellular process protein transporter activity | details |
| TreatCFM001877 | cyanate degradation S-methyl-L-methionine cycle nuclear pore transmembrane ring Selenocompound metabolism establishment of spindle pole body localization to nuclear envelope spindle pole body duplication cyanate catabolic process Nitrogen metabolism nuclear pore organization selenium compound metabolic process system development S-adenosylmethionine metabolic process pseudouridine synthesis cyanate hydratase activity cytosol vindoline and vinblastine biosynthesis transaminase activity structural constituent of nuclear pore pseudouridine synthase activity biosynthetic process | details |
Expression profiles
 Show details about module gene expression profiling |