TreatCFM001099's detailed annotation
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Protein: Yellow color--query protein Green color--interaction proteins. Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
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Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontolog |
|---|---|---|
| phosphopantothenate biosynthesis I | 0.001181649 | plantCyc |
| transcription factor TFIID complex | 0.008685119 | GO:0005669 |
| perinuclear region of cytoplasm | 0.008685119 | GO:0048471 |
| Ubiquitin_Proteasome_system, E2: UBC | 0.009653515 | ubs family |
| pantothenate kinase activity | 0.010758174 | GO:0004594 |
| cullin family protein binding | 0.010758174 | GO:0097602 |
| RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly | 0.010758174 | GO:0001129 |
| transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly | 0.010758174 | GO:0001075 |
| ubiquitin-like protein binding | 0.010758174 | GO:0032182 |
| Pantothenate and CoA biosynthesis | 0.019683965 | KEGG pathway |
| ubiquitin ligase complex | 0.021970465 | GO:0000151 |
| coenzyme A biosynthetic process | 0.022001432 | GO:0015937 |
| positive regulation of ubiquitin-protein transferase activity | 0.022001432 | GO:0051443 |
| transcription regulatory region DNA binding | 0.026094586 | GO:0044212 |
| ubiquitin conjugating enzyme binding | 0.026094586 | GO:0031624 |
| protein neddylation | 0.026390797 | GO:0045116 |
| positive regulation of transcription from RNA polymerase II promoter | 0.02812981 | GO:0045944 |
| macromolecule metabolic process | 0.02812981 | GO:0043170 |
| Basal transcription factors | 0.04022298 | KEGG pathway |
| chromatin binding | 0.047641357 | GO:0003682 |
| ubiquitin protein ligase binding | 0.047641357 | GO:0031625 |
Module member annotation
| Gene ID | Ortholog in Arabidopsis (Blast E-value) | Annotation in Arabidopsis |
|---|---|---|
| CRO_T000148 | AT2G13690 (2.00E-48) | PRLI-interacting factor, putative |
| CRO_T000888 | AT1G15860 (8.00E-67) | Domain of unknown function (DUF298) |
| CRO_T005192 | AT5G10360 (3.00E-71) | EMB3010|embryo defective 3010; RPS6B|Ribosomal protein small subunit 6b |
| CRO_T007406 | AT4G32180 (0) | ATPANK2|pantothenate kinase 2 |
| CRO_T011128 | AT1G73960 (0) | TAF2|TBP-associated factor 2 |
| CRO_T015333 | AT2G36290 (2.00E-124) | alpha/beta-Hydrolases superfamily protein |
| CRO_T023346 | AT1G17280 (3.00E-25) | UBC34|ubiquitin-conjugating enzyme 34 |
| CRO_T033322 | AT5G20580 (7.00E-131) |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TreatCFM000547 | phosphopantothenate biosynthesis I maltose alpha-glucosidase activity poly(G) binding alpha-1,4-glucosidase activity pantothenate kinase activity maltose metabolic process isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway coenzyme A biosynthetic process isopentenyl diphosphate biosynthetic process, mevalonate pathway hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc Pantothenate and CoA biosynthesis Circadian rhythm - plant NF-kappa B signaling pathway N-Glycan biosynthesis Protein_kinases_phosphatases, PPC:1.9.1: CRPK1 Like Kinase (Types 1 and 2) cellulose biosynthetic process root development regulation of catalytic activity unidimensional cell growth single-organism process sterol metabolic process defense response to bacterium | details |
| TreatCFM001164 | cytosolic large ribosomal subunit maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ubiquitin ligase complex Ribosome cytoplasmic translation poly(A) RNA binding Protein_kinases_phosphatases, PPC:2.2.1: Unknown Function Kinase structural constituent of ribosome ATG1/ULK1 kinase complex pre-autophagosomal structure membrane positive regulation of protein phosphorylation positive regulation of ubiquitin-protein transferase activity cullin family protein binding ubiquitin-ubiquitin ligase activity ubiquitin-like protein binding autophagosome assembly protein neddylation Autophagy - yeast ubiquitin conjugating enzyme binding protein kinase binding ATP-dependent peptidase activity Ubiquitin_Proteasome_system, E3: U-box | details |
| TreatCFM001238 | phosphopantothenate biosynthesis I RNA polymerase II core binding transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly pantothenate kinase activity transcription factor TFIID complex Cdc73/Paf1 complex protein targeting to Golgi regulation of histone H3-K4 methylation Pantothenate and CoA biosynthesis coenzyme A biosynthetic process histone methylation negative regulation of flower development macromolecule metabolic process positive regulation of transcription from RNA polymerase II promoter phospholipid translocation phospholipid-translocating ATPase activity transcription regulatory region DNA binding Basal transcription factors RNA degradation primary metabolic process positive regulation of transcription, DNA-templated chromatin binding Ubiquitin_Proteasome_system, E3 adaptor: DWD | details |
| TreatCFM001613 | hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc Protein_kinases_phosphatases, PPC:4.5.4: GSK3/Shaggy Like Protein Kinase Family ErbB signaling pathway trans, trans-farnesyl diphosphate biosynthesis methylerythritol phosphate pathway I methylerythritol phosphate pathway II mevalonate pathway I cytosol nuclear-transcribed mRNA catabolic process peptidyl-diphthamide biosynthetic process from peptidyl-histidine positive regulation of ubiquitin-protein transferase activity regulation of mitotic cell cycle ubiquitin-like protein binding cullin family protein binding diphthine synthase activity SUMO activating enzyme activity protein neddylation histone acetyltransferase activity ubiquitin conjugating enzyme binding large ribosomal subunit rRNA binding lipase activity protein sumoylation Ubiquitin mediated proteolysis histone acetylation ribosomal large subunit assembly cytoplasmic translation | details |
| TreatCFM001824 | formation of glycosidic bonds, GlycosylTransferases: GTnc oligosaccharide metabolic process sialylation protein N-linked glycosylation via asparagine sialyltransferase activity galactosyltransferase activity microtubule-based movement | details |
| TreatCFM002146 | Proteasome protochlorophyllide reductase activity transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly Basal transcription factors phytosphingosine metabolic process proteasome complex proteasome core complex, alpha-subunit complex 1,3-beta-D-glucan synthase complex transcription factor TFIID complex Transcription_related, Transcription factor: ERF transcription regulatory region DNA binding threonine-type endopeptidase activity 1,3-beta-D-glucan synthase activity 1,3-β-D-glucan biosynthesis phosphatidate metabolism, as a signaling molecule positive regulation of transcription from RNA polymerase II promoter (1->3)-beta-D-glucan biosynthetic process macromolecule metabolic process response to cold very long chain fatty acid biosynthesis I very long chain fatty acid biosynthesis II chromatin binding primary metabolic process | details |
Expression profiles
 Show details about module gene expression profiling |