TreatCFM001613's detailed annotation
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Protein: Yellow color--query protein Green color--interaction proteins. Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
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Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontolog |
|---|---|---|
| hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc | 0.00531577 | cazy family |
| Protein_kinases_phosphatases, PPC:4.5.4: GSK3/Shaggy Like Protein Kinase Family | 0.006195138 | kinase family |
| ErbB signaling pathway | 0.006200907 | KEGG pathway |
| trans, trans-farnesyl diphosphate biosynthesis | 0.009830939 | plantCyc |
| methylerythritol phosphate pathway I | 0.009830939 | plantCyc |
| methylerythritol phosphate pathway II | 0.009830939 | plantCyc |
| mevalonate pathway I | 0.009830939 | plantCyc |
| cytosol | 0.01477792 | GO:0005829 |
| nuclear-transcribed mRNA catabolic process | 0.02130484 | GO:0000956 |
| peptidyl-diphthamide biosynthetic process from peptidyl-histidine | 0.02130484 | GO:0017183 |
| positive regulation of ubiquitin-protein transferase activity | 0.02130484 | GO:0051443 |
| regulation of mitotic cell cycle | 0.023961572 | GO:0007346 |
| ubiquitin-like protein binding | 0.02450179 | GO:0032182 |
| cullin family protein binding | 0.02450179 | GO:0097602 |
| diphthine synthase activity | 0.02450179 | GO:0004164 |
| SUMO activating enzyme activity | 0.025720038 | GO:0019948 |
| protein neddylation | 0.028742417 | GO:0045116 |
| histone acetyltransferase activity | 0.031189977 | GO:0004402 |
| ubiquitin conjugating enzyme binding | 0.031189977 | GO:0031624 |
| large ribosomal subunit rRNA binding | 0.031189977 | GO:0070180 |
| lipase activity | 0.031189977 | GO:0016298 |
| protein sumoylation | 0.031923283 | GO:0016925 |
| Ubiquitin mediated proteolysis | 0.040723849 | KEGG pathway |
| histone acetylation | 0.043284154 | GO:0016573 |
| ribosomal large subunit assembly | 0.049552931 | GO:0000027 |
| cytoplasmic translation | 0.049552931 | GO:0002181 |
Module member annotation
| Gene ID | Ortholog in Arabidopsis (Blast E-value) | Annotation in Arabidopsis |
|---|---|---|
| CRO_T000888 | AT1G15860 (8.00E-67) | Domain of unknown function (DUF298) |
| CRO_T002476 | AT5G64610 (8.00E-43) | HAM1|histone acetyltransferase of the MYST family 1 |
| CRO_T002771 | AT1G18360 (2.00E-98) | alpha/beta-Hydrolases superfamily protein |
| CRO_T006403 | AT3G11490 (8.00E-115) | rac GTPase activating protein |
| CRO_T009019 | AT1G25260 (3.00E-92) | Ribosomal protein L10 family protein |
| CRO_T011784 | AT3G23640 (0) | HGL1|heteroglycan glucosidase 1 |
| CRO_T015088 | AT4G31790 (5.00E-131) | Tetrapyrrole (Corrin/Porphyrin) Methylases |
| CRO_T015875 | AT1G79690 (0) | atnudt3|nudix hydrolase homolog 3 |
| CRO_T022199 | AT1G06390 (0) | ATSK2-3|A. THALIANA SHAGGY-LIKE KINASE GROUP 2 3; ATSK22|SHAGGY-LIKE PROTEIN KINASE 22; BIL2|BIN2-LIKE 2; GSK1|GSK3/SHAGGY-like protein kinase 1 |
| CRO_T029820 | AT5G50580 (2.00E-30) | SAE1B|SUMO-activating enzyme 1B |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TreatCFM000295 | nuclear-transcribed mRNA catabolic process large ribosomal subunit rRNA binding cytoplasmic translation ribosomal large subunit assembly rRNA processing Transcription_related, Transcription factor: C2C2-Dof Transcription_related, Transcription factor: MYB-related preribosome, large subunit precursor Transcription_related, Transcription factor: C2H2 cytosolic large ribosomal subunit nucleolus | details |
| TreatCFM001099 | phosphopantothenate biosynthesis I transcription factor TFIID complex perinuclear region of cytoplasm Ubiquitin_Proteasome_system, E2: UBC pantothenate kinase activity cullin family protein binding RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly ubiquitin-like protein binding Pantothenate and CoA biosynthesis ubiquitin ligase complex coenzyme A biosynthetic process positive regulation of ubiquitin-protein transferase activity transcription regulatory region DNA binding ubiquitin conjugating enzyme binding protein neddylation positive regulation of transcription from RNA polymerase II promoter macromolecule metabolic process Basal transcription factors chromatin binding ubiquitin protein ligase binding | details |
| TreatCFM001164 | cytosolic large ribosomal subunit maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ubiquitin ligase complex Ribosome cytoplasmic translation poly(A) RNA binding Protein_kinases_phosphatases, PPC:2.2.1: Unknown Function Kinase structural constituent of ribosome ATG1/ULK1 kinase complex pre-autophagosomal structure membrane positive regulation of protein phosphorylation positive regulation of ubiquitin-protein transferase activity cullin family protein binding ubiquitin-ubiquitin ligase activity ubiquitin-like protein binding autophagosome assembly protein neddylation Autophagy - yeast ubiquitin conjugating enzyme binding protein kinase binding ATP-dependent peptidase activity Ubiquitin_Proteasome_system, E3: U-box | details |
| TreatCFM001439 | Alanine, aspartate and glutamate metabolism nuclear-transcribed mRNA catabolic process formation of glycosidic bonds, GlycosylTransferases: GTnc hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc Glycerolipid metabolism hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds large ribosomal subunit rRNA binding nitrogen compound metabolic process glycosyl compound metabolic process ribosomal large subunit assembly cytoplasmic translation rRNA processing beta-glucosidase activity | details |
| TreatCFM001440 | hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc glycosyl compound metabolic process Glycerolipid metabolism beta-glucosidase activity nuclear-transcribed mRNA catabolic process Alanine, aspartate and glutamate metabolism carbohydrate metabolic process hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds large ribosomal subunit rRNA binding cytoplasmic translation nitrogen compound metabolic process ribosomal large subunit assembly rRNA processing transferase activity, transferring acyl groups | details |
| TreatCFM001561 | rRNA modification box C/D snoRNP complex snoRNA binding small-subunit processome Ribosome biogenesis in eukaryotes phosphatidylethanolamine biosynthesis I malate transmembrane transport malate transmembrane transporter activity histone acetyltransferase activity histone acetylation Glycerophospholipid metabolism lyase activity plant-type vacuole membrane lipid metabolic process | details |
| TreatCFM001585 | Sulfur metabolism ncRNA metabolic process purine nucleobase transmembrane transport mRNA catabolic process 3'(2'),5'-bisphosphate nucleotidase activity purine nucleobase transmembrane transporter activity trans, trans-farnesyl diphosphate biosynthesis D-myo-inositol (1,4,5)-trisphosphate degradation methylerythritol phosphate pathway I methylerythritol phosphate pathway II mevalonate pathway I pyrimidine ribonucleosides salvage I phosphate-containing compound metabolic process macromolecular complex nuclease activity cytosol cytoplasm response to abscisic acid vacuole | details |
| TreatCFM001614 | ncRNA metabolic process nuclear-transcribed mRNA catabolic process mRNA catabolic process rRNA modification large ribosomal subunit rRNA binding lipase activity snoRNA binding nuclease activity Ribosome biogenesis in eukaryotes ribosomal large subunit assembly cytoplasmic translation box C/D snoRNP complex macromolecular complex rRNA processing lipid metabolic process preribosome, large subunit precursor | details |
| TreatCFM001688 | rRNA modification box C/D snoRNP complex snoRNA binding small-subunit processome Ribosome biogenesis in eukaryotes phosphatidylethanolamine biosynthesis I hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc Protein_kinases_phosphatases, PPC:4.2.4: SNF1 Related Protein Kinase (SnRK) histone acetylation Glycerophospholipid metabolism histone acetyltransferase activity MAPK signaling pathway - plant | details |
| TreatCFM001689 | CURI complex UTP-C complex hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc diphthine synthase activity peptidyl-diphthamide biosynthetic process from peptidyl-histidine tRNA export from nucleus Protein_kinases_phosphatases, PPC:4.2.4: SNF1 Related Protein Kinase (SnRK) Transcription_related, Transcription regulator: SET histone acetylation histone acetyltransferase activity MAPK signaling pathway - plant Ribosome biogenesis in eukaryotes small-subunit processome rRNA processing | details |
| TreatCFM001971 | Protein_kinases_phosphatases, PPC:4.5.4: GSK3/Shaggy Like Protein Kinase Family ErbB signaling pathway Linoleic acid metabolism UTP biosynthetic process nucleoside diphosphate phosphorylation GTP biosynthetic process CTP biosynthetic process oxylipin biosynthetic process ATP binding nucleoside diphosphate kinase activity 9-lipoxygenase and 9-allene oxide synthase pathway adenosine deoxyribonucleotides de novo biosynthesis CMP phosphorylation guanosine deoxyribonucleotides de novo biosynthesis I guanosine ribonucleotides de novo biosynthesis purine deoxyribonucleosides salvage pyrimidine deoxyribonucleotide phosphorylation pyrimidine deoxyribonucleotides de novo biosynthesis II pyrimidine ribonucleosides salvage I superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli) UTP and CTP de novo biosynthesis pyrimidine deoxyribonucleotides de novo biosynthesis I oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen traumatin and (Z)-3-hexen-1-yl acetate biosynthesis metal ion binding jasmonic acid biosynthesis pyrimidine ribonucleotides interconversion cytosol protein autophosphorylation fatty acid biosynthetic process response to abscisic acid Purine metabolism | details |
| TreatCFM002030 | nuclear-transcribed mRNA catabolic process large ribosomal subunit rRNA binding acetaldehyde biosynthesis I detoxification of reactive carbonyls in chloroplasts farnesylcysteine salvage pathway geraniol and geranial biosynthesis mannitol degradation II pyruvate fermentation to ethanol II traumatin and (Z)-3-hexen-1-yl acetate biosynthesis ribosomal large subunit assembly cytoplasmic translation rRNA processing preribosome, large subunit precursor Phenylpropanoid biosynthesis cytosolic large ribosomal subunit nucleolus Spliceosome Transcription_related, Transcription factor: ERF Transcription_related, Transcription factor: MYB | details |
| TreatCFM002135 | pyrimidine ribonucleosides salvage I Protein_kinases_phosphatases, PPC:4.2.1: Calcium Dependent Protein Kinase ATP binding SUMO activating enzyme activity calmodulin-dependent protein kinase activity calcium-dependent protein serine/threonine kinase activity regulation of mitotic cell cycle protein sumoylation | details |
Expression profiles
 Show details about module gene expression profiling |