TissueCFM000289's detailed annotation
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Protein: Yellow color--query protein Green color--interaction proteins. Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
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Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontolog |
|---|---|---|
| CST complex | 0.000531915 | GO:1990879 |
| single-stranded telomeric DNA binding | 0.002127502 | GO:0043047 |
| telomere capping | 0.002924883 | GO:0016233 |
| karyogamy | 0.002924883 | GO:0000741 |
| transcription coactivator activity | 0.004251233 | GO:0003713 |
| Ubiquitin_Proteasome_system, E3 adaptor: F-box | 0.036841041 | ubs family |
Module member annotation
| Gene ID | Ortholog in Arabidopsis (Blast E-value) | Annotation in Arabidopsis |
|---|---|---|
| CRO_T000379 | AT2G14045 (9.00E-23) | unknown protein |
| CRO_T020741 | AT1G07130 (3.00E-38) | ATSTN1; STN1|Nucleic acid-binding, OB-fold-like protein |
| CRO_T024359 | AT1G51550 (2.00E-133) | Kelch repeat-containing F-box family protein |
| CRO_T024532 | AT4G34265 (4.00E-12) | unknown protein |
| CRO_T026741 | AT1G28395 (5.00E-11) | unknown protein |
| CRO_T031318 | AT1G14780 (9.00E-71) | MAC/Perforin domain-containing protein |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TissueCFM000076 | 1,4-beta-D-xylan synthase activity protein kinase activator activity glucuronoxylan glucuronosyltransferase activity activation of protein kinase activity glucuronoxylan biosynthetic process large ribosomal subunit rRNA binding glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity plant-type secondary cell wall biogenesis chromatin silencing spliceosomal complex assembly cytoplasmic translation translational elongation formation of glycosidic bonds, GlycosylTransferases: GTnc mRNA binding Necroptosis U2 snRNP nuclear chromatin U2-type prespliceosome U12-type spliceosomal complex nucleosome preribosome, large subunit precursor catalytic step 2 spliceosome | details |
| TissueCFM000188 | details | |
| TissueCFM000200 | details | |
| TissueCFM000351 | Oxidative phosphorylation mitochondrial envelope vacuolar proton-transporting V-type ATPase, V0 domain Thiamine metabolism Fanconi anemia pathway vacuolar acidification mitochondrion proton-transporting ATPase activity, rotational mechanism cytochrome-c oxidase activity methylerythritol phosphate pathway I methylerythritol phosphate pathway II aerobic respiration I (cytochrome c) aerobic respiration III (alternative oxidase pathway) NAD/NADH phosphorylation and dephosphorylation Ubiquitin_Proteasome_system, E2: UBC NADH dehydrogenase (ubiquinone) activity ATP hydrolysis coupled proton transport | details |
| TissueCFM000568 | eumelanin biosynthesis mitochondrial envelope isomerase activity cytochrome-c oxidase activity hydrogen ion transmembrane transport Ubiquitin_Proteasome_system, E3 adaptor: F-box | details |
| TissueCFM000642 | Transcription_related, Transcription regulator: SWI/SNF-BAF60b karyogamy Golgi vesicle prefusion complex stabilization retrograde transport, vesicle recycling within Golgi Golgi transport complex transcription coactivator activity retrograde vesicle-mediated transport, Golgi to ER Golgi organization aerobic respiration I (cytochrome c) aerobic respiration III (alternative oxidase pathway) NAD/NADH phosphorylation and dephosphorylation | details |
| TissueCFM000785 | Fanconi anemia pathway solute:proton antiporter activity Transcription_related, Transcription factor: B3 | details |
| TissueCFM000803 | protein phosphorylation protein kinase activity ATP binding integral component of membrane Protein_kinases_phosphatases, PPC:1.10.1: Receptor Like Cytoplasmic Kinase VI Transcription_related, Transcription regulator: MBF1 microtubule minus-end binding transmembrane receptor protein tyrosine kinase activity protein serine/threonine kinase activity | details |
| TissueCFM000879 | 1,4-beta-D-xylan synthase activity glucuronoxylan glucuronosyltransferase activity glucuronoxylan biosynthetic process glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity plant-type secondary cell wall biogenesis formation of glycosidic bonds, GlycosylTransferases: GTnc organic cyclic compound binding heterocyclic compound binding cell wall organization MAPK signaling pathway - plant RNA transport | details |
| TissueCFM000913 | mRNA export from nucleus in response to heat stress recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex positive regulation of translational initiation methylerythritol phosphate pathway I methylerythritol phosphate pathway II transcription initiation from RNA polymerase II promoter nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay cytoplasmic mRNA processing body DNA-directed RNA polymerase II, core complex single-stranded RNA binding translation initiation factor binding single-stranded DNA binding Thiamine metabolism DNA-directed RNA polymerase activity DNA replication | details |
| TissueCFM000914 | mRNA export from nucleus in response to heat stress recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex positive regulation of translational initiation methylerythritol phosphate pathway I methylerythritol phosphate pathway II transcription initiation from RNA polymerase II promoter nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay DNA-directed RNA polymerase II, core complex cytoplasmic mRNA processing body single-stranded RNA binding Thiamine metabolism translation initiation factor binding single-stranded DNA binding DNA-directed RNA polymerase activity | details |
| TissueCFM001069 | SAGA-type complex spermine and spermidine degradation III Protein_kinases_phosphatases, PPC:2.1.2: Ankyrin Repeat Domain Kinase chaperone binding | details |
Expression profiles
 Show details about module gene expression profiling |