TissueCFM000785's detailed annotation
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Protein: Yellow color--query protein Green color--interaction proteins. Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
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Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontolog |
|---|---|---|
| Fanconi anemia pathway | 0.018393729 | KEGG pathway |
| solute:proton antiporter activity | 0.027546152 | GO:0015299 |
| Transcription_related, Transcription factor: B3 | 0.035986871 | TF family |
Module member annotation
| Gene ID | Ortholog in Arabidopsis (Blast E-value) | Annotation in Arabidopsis |
|---|---|---|
| CRO_T006829 | AT4G24190 (1.00E-50) | AtHsp90-7|HEAT SHOCK PROTEIN 90-7; AtHsp90.7|HEAT SHOCK PROTEIN 90.7; SHD|SHEPHERD |
| CRO_T014908 | - | - |
| CRO_T018911 | AT5G49210 (1.00E-30) | unknown protein |
| CRO_T019988 | AT1G78790 (5.00E-14) | unknown protein |
| CRO_T021753 | - | - |
| CRO_T024359 | AT1G51550 (2.00E-133) | Kelch repeat-containing F-box family protein |
| CRO_T031318 | AT1G14780 (9.00E-71) | MAC/Perforin domain-containing protein |
| CRO_T031546 | AT1G06970 (4.00E-97) | CHX14|cation/hydrogen exchanger 14 |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TissueCFM000076 | 1,4-beta-D-xylan synthase activity protein kinase activator activity glucuronoxylan glucuronosyltransferase activity activation of protein kinase activity glucuronoxylan biosynthetic process large ribosomal subunit rRNA binding glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity plant-type secondary cell wall biogenesis chromatin silencing spliceosomal complex assembly cytoplasmic translation translational elongation formation of glycosidic bonds, GlycosylTransferases: GTnc mRNA binding Necroptosis U2 snRNP nuclear chromatin U2-type prespliceosome U12-type spliceosomal complex nucleosome preribosome, large subunit precursor catalytic step 2 spliceosome | details |
| TissueCFM000091 | Ubiquitin_Proteasome_system, E3 adaptor: DWD mitochondrial respiratory chain complex IV assembly glucose catabolic process protein targeting mitochondrial respiratory chain complex I assembly glucan 1,3-alpha-glucosidase activity DNA replication factor A complex protein import into mitochondrial matrix Prp19 complex mitochondrial inner membrane presequence translocase complex Cul4-RING E3 ubiquitin ligase complex Transcriptional misregulation in cancers precatalytic spliceosome catalytic step 2 spliceosome nucleosome N-Glycan biosynthesis mRNA splicing, via spliceosome | details |
| TissueCFM000188 | details | |
| TissueCFM000200 | details | |
| TissueCFM000289 | CST complex single-stranded telomeric DNA binding telomere capping karyogamy transcription coactivator activity Ubiquitin_Proteasome_system, E3 adaptor: F-box | details |
| TissueCFM000351 | Oxidative phosphorylation mitochondrial envelope vacuolar proton-transporting V-type ATPase, V0 domain Thiamine metabolism Fanconi anemia pathway vacuolar acidification mitochondrion proton-transporting ATPase activity, rotational mechanism cytochrome-c oxidase activity methylerythritol phosphate pathway I methylerythritol phosphate pathway II aerobic respiration I (cytochrome c) aerobic respiration III (alternative oxidase pathway) NAD/NADH phosphorylation and dephosphorylation Ubiquitin_Proteasome_system, E2: UBC NADH dehydrogenase (ubiquinone) activity ATP hydrolysis coupled proton transport | details |
| TissueCFM000568 | eumelanin biosynthesis mitochondrial envelope isomerase activity cytochrome-c oxidase activity hydrogen ion transmembrane transport Ubiquitin_Proteasome_system, E3 adaptor: F-box | details |
| TissueCFM000803 | protein phosphorylation protein kinase activity ATP binding integral component of membrane Protein_kinases_phosphatases, PPC:1.10.1: Receptor Like Cytoplasmic Kinase VI Transcription_related, Transcription regulator: MBF1 microtubule minus-end binding transmembrane receptor protein tyrosine kinase activity protein serine/threonine kinase activity | details |
| TissueCFM000879 | 1,4-beta-D-xylan synthase activity glucuronoxylan glucuronosyltransferase activity glucuronoxylan biosynthetic process glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity plant-type secondary cell wall biogenesis formation of glycosidic bonds, GlycosylTransferases: GTnc organic cyclic compound binding heterocyclic compound binding cell wall organization MAPK signaling pathway - plant RNA transport | details |
| TissueCFM000913 | mRNA export from nucleus in response to heat stress recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex positive regulation of translational initiation methylerythritol phosphate pathway I methylerythritol phosphate pathway II transcription initiation from RNA polymerase II promoter nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay cytoplasmic mRNA processing body DNA-directed RNA polymerase II, core complex single-stranded RNA binding translation initiation factor binding single-stranded DNA binding Thiamine metabolism DNA-directed RNA polymerase activity DNA replication | details |
| TissueCFM000914 | mRNA export from nucleus in response to heat stress recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex positive regulation of translational initiation methylerythritol phosphate pathway I methylerythritol phosphate pathway II transcription initiation from RNA polymerase II promoter nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay DNA-directed RNA polymerase II, core complex cytoplasmic mRNA processing body single-stranded RNA binding Thiamine metabolism translation initiation factor binding single-stranded DNA binding DNA-directed RNA polymerase activity | details |
| TissueCFM001069 | SAGA-type complex spermine and spermidine degradation III Protein_kinases_phosphatases, PPC:2.1.2: Ankyrin Repeat Domain Kinase chaperone binding | details |
| TissueCFM001218 | xylan biosynthesis formation of glycosidic bonds, GlycosylTransferases: GTnc regulation of defense response negative regulation of nucleic acid-templated transcription regulation of jasmonic acid mediated signaling pathway response to wounding transcription corepressor activity Transcription_related, Transcription factor: B3 ADP binding ribosome biogenesis defense response | details |
| TissueCFM001642 | interphase microtubule nucleation by interphase microtubule organizing center centrosome duplication meiotic nuclear division response to nematode detection of light stimulus glucose catabolic process protein targeting mitotic spindle assembly growth cortical microtubule organization microtubule minus-end binding signaling receptor activity gamma-tubulin binding intracellular transport cellular protein modification process Transcriptional misregulation in cancers Lysosome equatorial microtubule organizing center gamma-tubulin complex structural constituent of cytoskeleton membrane coat nucleosome protein heterodimerization activity protein transport | details |
Expression profiles
 Show details about module gene expression profiling |