TissueCFM001672's detailed annotation
|
Protein: Yellow color--query protein Green color--interaction proteins. Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
| This network produced by cytoscapeweb |
Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontolog |
|---|---|---|
| protein transporter activity | 1.44E-06 | GO:0008565 |
| Ubiquitin_Proteasome_system, E3 adaptor: Cullin | 0.002892987 | ubs family |
| vesicle-mediated transport | 0.003180331 | GO:0016192 |
| MAPK signaling pathway - fly | 0.012061596 | KEGG pathway |
| ribosomal protein import into nucleus | 0.013731167 | GO:0006610 |
| protein import into nucleus, translocation | 0.013731167 | GO:0000060 |
| protein import into nucleus, docking | 0.013731167 | GO:0000059 |
| vacuolar transport | 0.013731167 | GO:0007034 |
| intracellular transport | 0.013731167 | GO:0046907 |
| NLS-bearing protein import into nucleus | 0.015687198 | GO:0006607 |
| nuclear localization sequence binding | 0.017288255 | GO:0008139 |
| Ran GTPase binding | 0.017288255 | GO:0008536 |
| protein import into nucleus | 0.018863623 | GO:0006606 |
| nuclear envelope | 0.021355448 | GO:0005635 |
| nuclear periphery | 0.021355448 | GO:0034399 |
| Golgi apparatus part | 0.021355448 | GO:0044431 |
| nuclear membrane | 0.021355448 | GO:0031965 |
| cullin-RING ubiquitin ligase complex | 0.021355448 | GO:0031461 |
| clathrin adaptor complex | 0.021355448 | GO:0030131 |
| ubiquitin protein ligase binding | 0.0217778 | GO:0031625 |
| Peroxisome | 0.029222416 | KEGG pathway |
| protein ubiquitination involved in ubiquitin-dependent protein catabolic process | 0.03725689 | GO:0042787 |
| ubiquitin protein ligase activity | 0.043109545 | GO:0061630 |
Module member annotation
| Gene ID | Ortholog in Arabidopsis (Blast E-value) | Annotation in Arabidopsis |
|---|---|---|
| CRO_T005461 | AT2G31660 (0) | EMA1|enhanced miRNA activity 1; SAD2|SUPER SENSITIVE TO ABA AND DROUGHT2; URM9|UNARMED 9 |
| CRO_T007849 | AT2G16950 (0) | ATTRN1|TRANSPORTIN 1 |
| CRO_T009803 | AT1G02980 (0) | CUL2|cullin 2 |
| CRO_T011576 | AT4G05530 (3.00E-25) | IBR1|indole-3-butyric acid response 1; SDRA|SHORT-CHAIN DEHYDROGENASE/REDUCTASE A |
| CRO_T014604 | AT4G19490 (0) | ATVPS54|VPS54 HOMOLOG |
| CRO_T023926 | AT3G23200 (3.00E-29) | Uncharacterised protein family (UPF0497) |
| CRO_T033186 | AT1G23900 (1.00E-24) | GAMMA-ADAPTIN 1|gamma-adaptin 1; Gamma-ADR|Gamma-adaptin |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TissueCFM001125 | 3-oxo-5-alpha-steroid 4-dehydrogenase activity sterol 5-alpha reductase activity progesterone 5-alpha-reductase activity brassinosteroid biosynthesis I brassinosteroid biosynthesis II protein phosphatase type 2A regulator activity protein phosphatase type 2A complex clathrin adaptor complex Brassinosteroid biosynthesis protein transporter activity regulation of protein phosphatase type 2A activity Endocytosis mRNA surveillance pathway brassinosteroid biosynthetic process | details |
| TissueCFM001146 | transcriptional repressor complex Golgi apparatus part Insulin signaling pathway Steroid biosynthesis intracellular transport vacuolar transport Cell cycle Transcription_related, Transcription factor: MYB-related Transcription_related, Transcription regulator: SNF2 exocyst cell part histone binding exocytosis membrane vesicle-mediated transport | details |
| TissueCFM001427 | vesicle-mediated transport intracellular protein transport transcriptional repressor complex Golgi apparatus part intracellular transport Cell cycle vacuolar transport Lysosome Transcription_related, Transcription factor: MYB-related very long chain fatty acid biosynthesis I membrane coat | details |
| TissueCFM001447 | vesicle-mediated transport protein transporter activity intracellular protein transport Ubiquitin_Proteasome_system, E3 adaptor: Cullin intracellular transport vacuolar transport MAPK signaling pathway - fly protein import into nucleus nuclear envelope cullin-RING ubiquitin ligase complex membrane coat clathrin adaptor complex Golgi apparatus part cytosol protein ubiquitination involved in ubiquitin-dependent protein catabolic process Lysosome Ran GTPase binding ubiquitin protein ligase binding signal transduction Endocytosis | details |
| TissueCFM001448 | Protein processing in endoplasmic reticulum internal protein amino acid acetylation N-terminal peptidyl-glutamic acid acetylation N-terminal peptidyl-serine acetylation peptide-serine-N-acetyltransferase activity peptide-glutamate-N-acetyltransferase activity NatA complex Golgi apparatus part Transcription_related, Transcription regulator: GNAT Ubiquitin_Proteasome_system, E3 adaptor: Cullin intracellular transport cytosolic ribosome cullin-RING ubiquitin ligase complex COPII vesicle coat vacuolar transport mRNA surveillance pathway ER to Golgi vesicle-mediated transport protein ubiquitination involved in ubiquitin-dependent protein catabolic process vesicle-mediated transport | details |
| TissueCFM001450 | Mitophagy - yeast Transcription_related, Transcription regulator: IWS1 ribosomal protein import into nucleus protein import into nucleus, docking transcription elongation from RNA polymerase II promoter protein import into nucleus, translocation Transcription_related, Transcription factor: Orphans NLS-bearing protein import into nucleus vesicle docking nuclear periphery nuclear membrane elongin complex nuclear localization sequence binding exocytosis exocyst protein transporter activity | details |
| TissueCFM001580 | Protein_kinases_phosphatases, PPC:2.1.4: GmPK6/AtMRK1 Family Ubiquitin_Proteasome_system, E3 adaptor: Cullin 3-phosphoinositide biosynthesis phosphoric ester hydrolase activity transcription regulatory region sequence-specific DNA binding chromatin chromatin silencing complex cullin-RING ubiquitin ligase complex vacuole organization heterochromatin assembly phosphatidylinositol-3-phosphate biosynthetic process regulation of cell shape chromatin silencing Wnt signaling pathway Endocytosis peptidyl-serine phosphorylation protein ubiquitination involved in ubiquitin-dependent protein catabolic process regulation of cellular process Protein processing in endoplasmic reticulum ubiquitin protein ligase binding chromatin binding | details |
| TissueCFM001602 | Tight junction regulation of lipid metabolic process clathrin adaptor complex chloroplast mitochondrion malate metabolic process malate dehydrogenase (decarboxylating) (NAD+) activity benzoate biosynthesis I (CoA-dependent, β-oxidative) gluconeogenesis I triacylglycerol degradation cobalt ion binding intracellular protein transport oxidation-reduction process vesicle-mediated transport Endocytosis 2-alkenal reductase [NAD(P)] activity protein transporter activity protein homodimerization activity NAD binding | details |
| TissueCFM001659 | signal transduction MAPK signaling pathway - fly protein import into nucleus vesicle docking regulation of protein phosphatase type 2A activity protein phosphatase type 2A regulator activity Ran GTPase binding exocytosis mRNA surveillance pathway nuclear envelope protein phosphatase type 2A complex exocyst cytosol protein transporter activity cell cell redox homeostasis | details |
| TissueCFM001660 | protein transporter activity rosmarinic acid biosynthesis I rosmarinic acid biosynthesis II hydroxyphenylpyruvate reductase activity 4-hydroxybenzoate biosynthesis I (eukaryotes) signal transduction oxidative photosynthetic carbon pathway glyoxylate reductase (NADP) activity hydroxypyruvate reductase activity protein phosphatase type 2A regulator activity protein import into nucleus, docking protein import into nucleus, translocation ribosomal protein import into nucleus regulation of protein phosphatase type 2A activity nuclear localization sequence binding Ran GTPase binding MAPK signaling pathway - fly NLS-bearing protein import into nucleus nuclear periphery protein phosphatase type 2A complex clathrin adaptor complex nuclear membrane nuclear envelope protein import into nucleus | details |
| TissueCFM001788 | protein transporter activity protein import into nucleus, translocation ribosomal protein import into nucleus protein import into nucleus, docking nuclear localization sequence binding Ran GTPase binding NLS-bearing protein import into nucleus clathrin adaptor complex nuclear periphery nuclear membrane vesicle-mediated transport intracellular protein transport MAPK signaling pathway - fly protein import into nucleus nuclear envelope Lysosome plastoglobule signal transduction Endocytosis | details |
Expression profiles
 Show details about module gene expression profiling |