TissueCFM000444's detailed annotation
|
Protein: Yellow color--query protein Green color--interaction proteins. Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
| This network produced by cytoscapeweb |
Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontolog |
|---|---|---|
| actin filament-based process | 0.004432362 | GO:0030029 |
| ubiquinone biosynthetic process | 0.00775205 | GO:0006744 |
| non-hydrolytic cleavage of glycosidic bonds, Polysaccharide Lyases: PL4 | 0.013511832 | cazy family |
| Ubiquitin_Proteasome_system, DUB: OTU | 0.013511832 | ubs family |
| pectate lyase activity | 0.019907944 | GO:0030570 |
| structural constituent of cytoskeleton | 0.019907944 | GO:0005200 |
| Thiamine metabolism | 0.023364176 | KEGG pathway |
| Lysosome | 0.026222653 | KEGG pathway |
| pectin catabolic process | 0.028640642 | GO:0045490 |
| single-organism metabolic process | 0.028640642 | GO:0044710 |
| lipid binding | 0.03161173 | GO:0008289 |
| Pentose and glucuronate interconversions | 0.046288966 | KEGG pathway |
Module member annotation
| Gene ID | Ortholog in Arabidopsis (Blast E-value) | Annotation in Arabidopsis |
|---|---|---|
| CRO_T000166 | AT3G51730 (4.00E-07) | saposin B domain-containing protein |
| CRO_T002095 | AT1G04680 (1.00E-140) | Pectin lyase-like superfamily protein |
| CRO_T009580 | AT5G04830 (4.00E-57) | Nuclear transport factor 2 (NTF2) family protein |
| CRO_T013000 | AT1G11930 (1.00E-106) | Predicted pyridoxal phosphate-dependent enzyme, YBL036C type |
| CRO_T019891 | AT1G19140 (2.00E-87) | unknown protein |
| CRO_T023344 | AT3G16990 (4.00E-60) | Haem oxygenase-like, multi-helical |
| CRO_T025049 | AT2G37620 (2.00E-22) | AAc1|ARABIDOPSIS ACTIN 1; ACT1|actin 1 |
| CRO_T028420 | AT5G13100 (7.00E-133) | unknown protein |
| CRO_T029985 | AT5G10730 (2.00E-20) | NAD(P)-binding Rossmann-fold superfamily protein |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TissueCFM000241 | homogentisate 1,2-dioxygenase activity homogentisate catabolic process tyrosine catabolic process non-hydrolytic cleavage of glycosidic bonds, Polysaccharide Lyases: PL4 L-phenylalanine catabolic process pectate lyase activity Tyrosine metabolism pectin catabolic process Pentose and glucuronate interconversions integral component of membrane Purine metabolism | details |
| TissueCFM000300 | hypoxanthine transport guanine transmembrane transporter activity adenine import across plasma membrane uracil import across plasma membrane solute:cation symporter activity adenine transmembrane transporter activity uracil transmembrane transporter activity guanine import across plasma membrane ubiquinone biosynthetic process cation transmembrane transport Protein_kinases_phosphatases, PPC:1.2.2: Receptor Like Cytoplasmic Kinase VII lipid binding | details |
| TissueCFM000514 | L-homoserine biosynthesis anaphase-promoting complex binding ubiquitin-protein transferase activator activity aspartate kinase activity L-lysine biosynthesis VI amino acid binding 2-Oxocarboxylic acid metabolism Ubiquitin mediated proteolysis cellular amino acid biosynthetic process regulation of catalytic activity Ubiquitin_Proteasome_system, E3 adaptor: DWD vesicle-mediated transport | details |
| TissueCFM000537 | non-hydrolytic cleavage of glycosidic bonds, Polysaccharide Lyases: PL4 pectate lyase activity regulation of nucleobase-containing compound metabolic process homogentisate catabolic process tyrosine catabolic process pectin catabolic process positive regulation of chromatin organization trans, trans-farnesyl diphosphate biosynthesis geranylgeranyl diphosphate biosynthesis L-cysteine biosynthesis I polyisoprenoid biosynthesis superpathway of geranylgeranyl diphosphate biosynthesis II (via MEP) superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate) homogentisate 1,2-dioxygenase activity Z-farnesyl diphosphate synthase activity Atg8 ligase activity D-myo-inositol (1,4,5)-trisphosphate degradation farnesyl diphosphate biosynthetic process regulation of macromolecule metabolic process L-phenylalanine catabolic process mitotic chromosome condensation mitophagy nucleophagy Pentose and glucuronate interconversions Cell cycle - yeast RIG-I-like receptor signaling pathway Tyrosine metabolism autophagosome assembly condensed chromosome cytoplasmic ubiquitin ligase complex | details |
| TissueCFM000635 | S-methyl-5-thio-α-D-ribose 1-phosphate degradation adenine import across plasma membrane hypoxanthine transport guanine import across plasma membrane uracil import across plasma membrane L-methionine biosynthetic process from S-adenosylmethionine ubiquinone biosynthetic process adenine transmembrane transporter activity uracil transmembrane transporter activity solute:cation symporter activity guanine transmembrane transporter activity L-methionine biosynthetic process from methylthioadenosine Cysteine and methionine metabolism cation transmembrane transport S-methyl-5-thioribose-1-phosphate isomerase activity Ubiquitin_Proteasome_system, DUB: OTU formation of glycosidic bonds, GlycosylTransferases: GTnc microtubule-based movement | details |
| TissueCFM000733 | Transcription_related, Transcription factor: BBR-BPC L-valine degradation I non-hydrolytic cleavage of glycosidic bonds, Polysaccharide Lyases: PL4 D-gluconate catabolic process Carbon metabolism gluconokinase activity receptor activity aldehyde dehydrogenase (NAD) activity malonate-semialdehyde dehydrogenase (acetylating) activity protein phosphatase inhibitor activity pectate lyase activity abscisic acid binding methylmalonate-semialdehyde dehydrogenase (acylating) activity regulation of protein serine/threonine phosphatase activity | details |
| TissueCFM000937 | cytoplasmic ubiquitin ligase complex trans, trans-farnesyl diphosphate biosynthesis geranylgeranyl diphosphate biosynthesis polyisoprenoid biosynthesis superpathway of geranylgeranyl diphosphate biosynthesis II (via MEP) superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate) Atg8 ligase activity Z-farnesyl diphosphate synthase activity actin filament-based process mitophagy farnesyl diphosphate biosynthetic process nucleophagy autophagosome assembly geranyltranstransferase activity non-hydrolytic cleavage of glycosidic bonds, Polysaccharide Lyases: PL4 Transcription_related, Transcription factor: C2C2-GATA dimethylallyltranstransferase activity pectate lyase activity structural constituent of cytoskeleton Autophagy - animal Terpenoid backbone biosynthesis pectin catabolic process protein transport Pentose and glucuronate interconversions | details |
| TissueCFM001241 | uracil degradation I (reductive) non-hydrolytic cleavage of glycosidic bonds, Polysaccharide Lyases: PL4 protein targeting to membrane uracil catabolic process beta-ureidopropionase activity MAPK signaling pathway - yeast Pyrimidine metabolism SNARE interactions in vesicular transport vesicle docking microtubule-based movement vesicle fusion response to stimulus pectin catabolic process pectate lyase activity protein domain specific binding Pentose and glucuronate interconversions SNARE binding SNAP receptor activity microtubule motor activity | details |
| TissueCFM001576 | pyruvate decarboxylation to acetyl CoA tyrosine catabolic process homogentisate catabolic process actin filament-based process homogentisate 1,2-dioxygenase activity Atg8 ligase activity nucleophagy L-phenylalanine catabolic process mitophagy cytoplasmic ubiquitin ligase complex autophagosome assembly Autophagy - animal Tyrosine metabolism Transcription_related, Transcription factor: C2C2-GATA cytosolic ribosome structural constituent of cytoskeleton | details |
| TissueCFM001759 | regulation of nucleobase-containing compound metabolic process positive regulation of chromatin organization xylogalacturonan biosynthesis regulation of macromolecule metabolic process hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc non-hydrolytic cleavage of glycosidic bonds, Polysaccharide Lyases: PL4 xyloglucan metabolic process cell wall biogenesis pectin catabolic process single-organism cellular process pectate lyase activity xyloglucan:xyloglucosyl transferase activity Pentose and glucuronate interconversions Purine metabolism | details |
| TissueCFM001826 | Transcription_related, Transcription regulator: Jumonji response to stress single-organism metabolic process formation of glycosidic bonds, GlycosylTransferases: GTnc | details |
Expression profiles
 Show details about module gene expression profiling |