TissueCFM000733's detailed annotation
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Protein: Yellow color--query protein Green color--interaction proteins. Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
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Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontolog |
|---|---|---|
| Transcription_related, Transcription factor: BBR-BPC | 0.00531577 | TF family |
| L-valine degradation I | 0.007364388 | plantCyc |
| non-hydrolytic cleavage of glycosidic bonds, Polysaccharide Lyases: PL4 | 0.007960943 | cazy family |
| D-gluconate catabolic process | 0.015046147 | GO:0046177 |
| Carbon metabolism | 0.023134377 | KEGG pathway |
| gluconokinase activity | 0.024431124 | GO:0046316 |
| receptor activity | 0.025906347 | GO:0004872 |
| aldehyde dehydrogenase (NAD) activity | 0.025906347 | GO:0004029 |
| malonate-semialdehyde dehydrogenase (acetylating) activity | 0.025906347 | GO:0018478 |
| protein phosphatase inhibitor activity | 0.025906347 | GO:0004864 |
| pectate lyase activity | 0.025906347 | GO:0030570 |
| abscisic acid binding | 0.025906347 | GO:0010427 |
| methylmalonate-semialdehyde dehydrogenase (acylating) activity | 0.025906347 | GO:0004491 |
| regulation of protein serine/threonine phosphatase activity | 0.037575372 | GO:0080163 |
Module member annotation
| Gene ID | Ortholog in Arabidopsis (Blast E-value) | Annotation in Arabidopsis |
|---|---|---|
| CRO_T000091 | AT1G02920 (2.00E-06) | ATGST11|ARABIDOPSIS GLUTATHIONE S-TRANSFERASE 11; GST11|GLUTATHIONE S-TRANSFERASE 11; GSTF7|glutathione S-transferase 7 |
| CRO_T000939 | AT2G16790 (3.00E-36) | P-loop containing nucleoside triphosphate hydrolases superfamily protein |
| CRO_T002095 | AT1G04680 (1.00E-140) | Pectin lyase-like superfamily protein |
| CRO_T010334 | AT1G68120 (6.00E-33) | BPC3|basic pentacysteine 3 |
| CRO_T014947 | AT1G48550 (1.00E-101) | Vacuolar protein sorting-associated protein 26 |
| CRO_T015078 | - | - |
| CRO_T016138 | AT1G01360 (6.00E-79) | PYL9|PYRABACTIN RESISTANCE 1-LIKE 9; RCAR1|regulatory component of ABA receptor 1 |
| CRO_T017141 | AT2G14170 (0) | ALDH6B2|aldehyde dehydrogenase 6B2 |
| CRO_T030288 | AT4G25310 (6.00E-57) | 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein |
| CRO_T030534 | AT2G03810 (1.00E-04) | 18S pre-ribosomal assembly protein gar2-related |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TissueCFM000241 | homogentisate 1,2-dioxygenase activity homogentisate catabolic process tyrosine catabolic process non-hydrolytic cleavage of glycosidic bonds, Polysaccharide Lyases: PL4 L-phenylalanine catabolic process pectate lyase activity Tyrosine metabolism pectin catabolic process Pentose and glucuronate interconversions integral component of membrane Purine metabolism | details |
| TissueCFM000444 | actin filament-based process ubiquinone biosynthetic process non-hydrolytic cleavage of glycosidic bonds, Polysaccharide Lyases: PL4 Ubiquitin_Proteasome_system, DUB: OTU pectate lyase activity structural constituent of cytoskeleton Thiamine metabolism Lysosome pectin catabolic process single-organism metabolic process lipid binding Pentose and glucuronate interconversions | details |
| TissueCFM000537 | non-hydrolytic cleavage of glycosidic bonds, Polysaccharide Lyases: PL4 pectate lyase activity regulation of nucleobase-containing compound metabolic process homogentisate catabolic process tyrosine catabolic process pectin catabolic process positive regulation of chromatin organization trans, trans-farnesyl diphosphate biosynthesis geranylgeranyl diphosphate biosynthesis L-cysteine biosynthesis I polyisoprenoid biosynthesis superpathway of geranylgeranyl diphosphate biosynthesis II (via MEP) superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate) homogentisate 1,2-dioxygenase activity Z-farnesyl diphosphate synthase activity Atg8 ligase activity D-myo-inositol (1,4,5)-trisphosphate degradation farnesyl diphosphate biosynthetic process regulation of macromolecule metabolic process L-phenylalanine catabolic process mitotic chromosome condensation mitophagy nucleophagy Pentose and glucuronate interconversions Cell cycle - yeast RIG-I-like receptor signaling pathway Tyrosine metabolism autophagosome assembly condensed chromosome cytoplasmic ubiquitin ligase complex | details |
| TissueCFM000750 | clathrin-mediated endocytosis clathrin heavy chain binding Transcription_related, Transcription factor: BBR-BPC leucopelargonidin and leucocyanidin biosynthesis phosphatidate metabolism, as a signaling molecule structural molecule activity clathrin vesicle coat Transcription_related, Transcription factor: GRAS | details |
| TissueCFM000937 | cytoplasmic ubiquitin ligase complex trans, trans-farnesyl diphosphate biosynthesis geranylgeranyl diphosphate biosynthesis polyisoprenoid biosynthesis superpathway of geranylgeranyl diphosphate biosynthesis II (via MEP) superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate) Atg8 ligase activity Z-farnesyl diphosphate synthase activity actin filament-based process mitophagy farnesyl diphosphate biosynthetic process nucleophagy autophagosome assembly geranyltranstransferase activity non-hydrolytic cleavage of glycosidic bonds, Polysaccharide Lyases: PL4 Transcription_related, Transcription factor: C2C2-GATA dimethylallyltranstransferase activity pectate lyase activity structural constituent of cytoskeleton Autophagy - animal Terpenoid backbone biosynthesis pectin catabolic process protein transport Pentose and glucuronate interconversions | details |
| TissueCFM001037 | mitochondrion hydrogen ion transmembrane transporter activity ATP synthesis coupled proton transport quinone binding NAD binding Oxidative phosphorylation NADH dehydrogenase activity phosphatidate metabolism, as a signaling molecule respiratory chain NADH dehydrogenase (ubiquinone) activity oxidation-reduction process | details |
| TissueCFM001241 | uracil degradation I (reductive) non-hydrolytic cleavage of glycosidic bonds, Polysaccharide Lyases: PL4 protein targeting to membrane uracil catabolic process beta-ureidopropionase activity MAPK signaling pathway - yeast Pyrimidine metabolism SNARE interactions in vesicular transport vesicle docking microtubule-based movement vesicle fusion response to stimulus pectin catabolic process pectate lyase activity protein domain specific binding Pentose and glucuronate interconversions SNARE binding SNAP receptor activity microtubule motor activity | details |
| TissueCFM001242 | tRNA 3'-trailer cleavage, endonucleolytic D-gluconate catabolic process protein targeting to membrane 3'-tRNA processing endoribonuclease activity gluconokinase activity vesicle docking vesicle fusion response to stimulus SNARE binding SNAP receptor activity SNARE interactions in vesicular transport | details |
| TissueCFM001354 | Transcription_related, Transcription factor: BBR-BPC Transcription_related, Transcription regulator: SWI/SNF-BAF60b replication fork Rad51B-Rad51C-Rad51D-XRCC2 complex strand invasion regulation of cyclin-dependent protein serine/threonine kinase activity mitotic recombination regulation of mitotic cell cycle reciprocal meiotic recombination response to ionizing radiation meiotic DNA recombinase assembly Homologous recombination cellular water homeostasis water transport glycerol transport recombinase activity endodeoxyribonuclease activity four-way junction DNA binding water channel activity DNA-dependent ATPase activity glycerol channel activity single-stranded DNA binding double-stranded DNA binding ion transmembrane transport translational initiation translation initiation factor activity | details |
| TissueCFM001356 | alpha-1,2-mannosyltransferase activity protein N-glycosylation (eukaryotic, high mannose) formation of glycosidic bonds, GlycosylTransferases: GTnc Transcription_related, Transcription factor: BBR-BPC Glycosaminoglycan degradation mannosylation N-Glycan biosynthesis ER-associated ubiquitin-dependent protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process Transcription_related, Transcription factor: HB lipid binding | details |
| TissueCFM001380 | Transcription_related, Transcription factor: BBR-BPC response to oxidative stress glutathione-peroxide redox reactions reactive oxygen species degradation L-valine degradation I methylmalonate-semialdehyde dehydrogenase (acylating) activity glutathione peroxidase activity malonate-semialdehyde dehydrogenase (acetylating) activity regulation of mitotic cell cycle Arachidonic acid metabolism regulation of cyclin-dependent protein serine/threonine kinase activity aldehyde dehydrogenase (NAD) activity Transcription_related, Transcription factor: HB Glutathione metabolism glutathione transferase activity lipid binding | details |
| TissueCFM001442 | extrinsic component of mitochondrial inner membrane 3'-tRNA processing endoribonuclease activity gluconokinase activity tRNA 3'-trailer cleavage, endonucleolytic D-gluconate catabolic process ubiquinone biosynthetic process single-multicellular organism process single organism reproductive process RNA splicing DNA-templated transcription, initiation | details |
| TissueCFM001499 | leucopelargonidin and leucocyanidin biosynthesis phosphoprotein binding Transcription_related, Transcription factor: HB lipid binding dioxygenase activity | details |
| TissueCFM001576 | pyruvate decarboxylation to acetyl CoA tyrosine catabolic process homogentisate catabolic process actin filament-based process homogentisate 1,2-dioxygenase activity Atg8 ligase activity nucleophagy L-phenylalanine catabolic process mitophagy cytoplasmic ubiquitin ligase complex autophagosome assembly Autophagy - animal Tyrosine metabolism Transcription_related, Transcription factor: C2C2-GATA cytosolic ribosome structural constituent of cytoskeleton | details |
| TissueCFM001579 | Transcription_related, Transcription factor: BBR-BPC Transcription_related, Transcription factor: NF-YC L-valine degradation I RIG-I-like receptor signaling pathway phosphoprotein binding malonate-semialdehyde dehydrogenase (acetylating) activity methylmalonate-semialdehyde dehydrogenase (acylating) activity receptor activity abscisic acid binding protein phosphatase inhibitor activity aldehyde dehydrogenase (NAD) activity glutathione metabolic process abscisic acid-activated signaling pathway RNA secondary structure unwinding regulation of protein serine/threonine phosphatase activity negative regulation of catalytic activity Glutathione metabolism | details |
| TissueCFM001639 | L-cysteine biosynthesis I formation of glycosidic bonds, GlycosylTransferases: GTnc hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc plant-type cell wall organization cellular amino acid biosynthetic process cysteine biosynthetic process from serine cell wall cysteine synthase activity beta-galactosidase activity | details |
| TissueCFM001640 | Antigen processing and presentation cell wall hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc cytoplasmic, membrane-bounded vesicle plant-type cell wall organization protein catabolic process beta-galactosidase activity aspartic-type endopeptidase activity dioxygenase activity carbohydrate binding | details |
| TissueCFM001657 | leucopelargonidin and leucocyanidin biosynthesis phosphoprotein binding Protein_kinases_phosphatases, PPC:4.2.6: IRE/NPH/PI dependent/S6 Kinase Transcription_related, Transcription factor: HB water transport glycerol transport cellular water homeostasis glycerol channel activity water channel activity ion transmembrane transport lipid binding | details |
| TissueCFM001759 | regulation of nucleobase-containing compound metabolic process positive regulation of chromatin organization xylogalacturonan biosynthesis regulation of macromolecule metabolic process hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc non-hydrolytic cleavage of glycosidic bonds, Polysaccharide Lyases: PL4 xyloglucan metabolic process cell wall biogenesis pectin catabolic process single-organism cellular process pectate lyase activity xyloglucan:xyloglucosyl transferase activity Pentose and glucuronate interconversions Purine metabolism | details |
| TissueCFM001820 | pyruvate decarboxylation to acetyl CoA Carbon metabolism transferase activity, transferring acyl groups formate dehydrogenase (NAD+) activity Atg8 ligase activity homogentisate 1,2-dioxygenase activity phosphoglycerate dehydrogenase activity tyrosine catabolic process homogentisate catabolic process serine family amino acid biosynthetic process formate catabolic process Tyrosine metabolism L-phenylalanine catabolic process nucleophagy mitophagy cytoplasmic ubiquitin ligase complex Autophagy - animal autophagosome assembly cytosolic ribosome cytosol chloroplast part protein transport NAD binding dioxygenase activity | details |
Expression profiles
 Show details about module gene expression profiling |