TissueCFM000721's detailed annotation
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Protein: Yellow color--query protein Green color--interaction proteins. Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
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Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontolog |
|---|---|---|
| seleno-amino acid biosynthesis | 0.002067152 | plantCyc |
| cystathionine gamma-lyase activity | 0.008550514 | GO:0004123 |
| L-cysteine desulfhydrase activity | 0.008550514 | GO:0080146 |
| L-cystine L-cysteine-lyase (deaminating) | 0.008550514 | GO:0044540 |
| cystathionine beta-lyase activity | 0.008550514 | GO:0004121 |
| glucosinolate metabolic process | 0.008992348 | GO:0019760 |
| protein depalmitoylation | 0.008992348 | GO:0002084 |
| 'de novo' L-methionine biosynthetic process | 0.008992348 | GO:0071266 |
| palmitoyl-(protein) hydrolase activity | 0.011967536 | GO:0008474 |
| carboxylic ester hydrolase activity | 0.02419855 | GO:0052689 |
| poly(A) RNA binding | 0.029264113 | GO:0044822 |
| ribosome biogenesis | 0.034768203 | GO:0042254 |
| transferase activity, transferring hexosyl groups | 0.035180307 | GO:0016758 |
| mRNA splicing, via spliceosome | 0.043894866 | GO:0000398 |
| spliceosomal complex | 0.046636969 | GO:0005681 |
| cytoplasm | 0.046636969 | GO:0005737 |
| formation of glycosidic bonds, GlycosylTransferases: GTnc | 0.049602139 | cazy family |
Module member annotation
| Gene ID | Ortholog in Arabidopsis (Blast E-value) | Annotation in Arabidopsis |
|---|---|---|
| CRO_T007960 | AT1G32490 (0) | EMB2733|EMBRYO DEFECTIVE 2733; ESP3|ENHANCED SILENCING PHENOTYPE 3 |
| CRO_T008306 | AT1G51300 (1.00E-24) | alpha/beta-Hydrolases superfamily protein |
| CRO_T014617 | AT1G68570 (0) | NPF3.1|NRT1/ PTR family 3.1 |
| CRO_T015227 | AT2G43820 (5.00E-124) | ATSAGT1|salicylic acid glucosyltransferase 1; SGT1|UDP-glucose:salicylic acid glucosyltransferase 1; UGT74F2|UDP-glucosyltransferase 74F2 |
| CRO_T016369 | AT2G23970 (6.00E-35) | Class I glutamine amidotransferase-like superfamily protein |
| CRO_T018908 | AT1G06720 (0) | P-loop containing nucleoside triphosphate hydrolases superfamily protein |
| CRO_T025249 | AT3G01120 (1.00E-16) | AtCYS1|A. thaliana cystathionine gamma-synthetase 1; CGS|CYSTATHIONINE GAMMA-SYNTHASE; CGS1|CYSTATHIONINE GAMMA-SYNTHASE 1; MTO1|METHIONINE OVERACCUMULATION 1 |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TissueCFM000365 | seleno-amino acid biosynthesis protein depalmitoylation 'de novo' L-methionine biosynthetic process L-cystine L-cysteine-lyase (deaminating) L-cysteine desulfhydrase activity cystathionine gamma-lyase activity cystathionine beta-lyase activity palmitoyl-(protein) hydrolase activity Transcription_related, Transcription factor: C3H carboxylic ester hydrolase activity Base excision repair Glycerophospholipid metabolism Biosynthesis of amino acids 2-alkenal reductase [NAD(P)] activity | details |
| TissueCFM000777 | formation of glycosidic bonds, GlycosylTransferases: GTnc seleno-amino acid biosynthesis Various types of N-glycan biosynthesis cystathionine gamma-lyase activity L-cystine L-cysteine-lyase (deaminating) fucosyltransferase activity L-cysteine desulfhydrase activity cystathionine beta-lyase activity 'de novo' L-methionine biosynthetic process protein depalmitoylation fucosylation palmitoyl-(protein) hydrolase activity Golgi cisterna membrane biological regulation carboxylic ester hydrolase activity protein glycosylation Glycerophospholipid metabolism cell part Biosynthesis of amino acids 2-alkenal reductase [NAD(P)] activity protein binding | details |
| TissueCFM001001 | seleno-amino acid biosynthesis cystathionine gamma-lyase activity cystathionine beta-lyase activity L-cystine L-cysteine-lyase (deaminating) L-cysteine desulfhydrase activity Protein_kinases_phosphatases, PPC:2.1.3: CTR1/EDR1 Kinase 'de novo' L-methionine biosynthetic process chromosome eukaryotic translation initiation factor 3 complex eukaryotic 48S preinitiation complex eukaryotic 43S preinitiation complex chromosome organization MAP kinase kinase kinase activity MAPK cascade activation of MAPKK activity formation of translation preinitiation complex regulation of translational initiation Cell cycle | details |
| TissueCFM001677 | RNA degradation seleno-amino acid biosynthesis histone H3-K36 methylation translational frameshifting positive regulation of translational termination positive regulation of translational elongation 'de novo' L-methionine biosynthetic process histone H3-K4 methylation negative regulation of flower development L-cysteine desulfhydrase activity cystathionine beta-lyase activity L-cystine L-cysteine-lyase (deaminating) cystathionine gamma-lyase activity proteasome core complex, alpha-subunit complex Cul4-RING E3 ubiquitin ligase complex Transcription_related, Transcription regulator: DDT Proteasome Biosynthesis of amino acids Transcription_related, Transcription regulator: PHD Transcription_related, Transcription regulator: SNF2 threonine-type endopeptidase activity ribosome binding poly(A) RNA binding | details |
| TissueCFM001705 | rosmarinic acid biosynthesis I rosmarinic acid biosynthesis II sulfate activation for sulfonation hydrogen sulfide biosynthetic process oxidative photosynthetic carbon pathway male gamete generation protein depalmitoylation S-methyl-5-thio-α-D-ribose 1-phosphate degradation 4-hydroxybenzoate biosynthesis I (eukaryotes) Transcription_related, Transcription regulator: SNF2 adenylylsulfate kinase activity palmitoyl-(protein) hydrolase activity hydroxyphenylpyruvate reductase activity hydroxypyruvate reductase activity glyoxylate reductase (NADP) activity Glucagon signaling pathway L-aspartate:2-oxoglutarate aminotransferase activity L-phenylalanine:2-oxoglutarate aminotransferase activity carboxylic ester hydrolase activity Sulfur metabolism sulfate assimilation cytosol biosynthetic process Glycerophospholipid metabolism | details |
Expression profiles
 Show details about module gene expression profiling |