TissueCFM001710's detailed annotation
|
Protein: Yellow color--query protein Green color--interaction proteins. Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
| This network produced by cytoscapeweb |
Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontolog |
|---|---|---|
| ubiquitin-dependent protein catabolic process | 1.69E-06 | GO:0006511 |
| Ubiquitin_Proteasome_system, DUB: USP | 9.89E-06 | ubs family |
| protein deubiquitination | 3.78E-05 | GO:0016579 |
| interstrand cross-link repair | 0.002698776 | GO:0036297 |
| 1,3-β-D-glucan biosynthesis | 0.002834156 | plantCyc |
| (1->3)-beta-D-glucan biosynthetic process | 0.007079055 | GO:0006075 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 0.009029289 | GO:0016818 |
| Fanconi anemia pathway | 0.012195236 | KEGG pathway |
| Proteasome | 0.012195236 | KEGG pathway |
| thiol-dependent ubiquitin-specific protease activity | 0.012629801 | GO:0004843 |
| nuclease activity | 0.012629801 | GO:0004518 |
| thiol-dependent ubiquitinyl hydrolase activity | 0.012629801 | GO:0036459 |
| 1,3-beta-D-glucan synthase activity | 0.012629801 | GO:0003843 |
| 1,3-beta-D-glucan synthase complex | 0.014158109 | GO:0000148 |
| proteasome core complex, alpha-subunit complex | 0.014158109 | GO:0019773 |
| threonine-type endopeptidase activity | 0.014278428 | GO:0004298 |
| nucleic acid phosphodiester bond hydrolysis | 0.0241887 | GO:0090305 |
Module member annotation
| Gene ID | Ortholog in Arabidopsis (Blast E-value) | Annotation in Arabidopsis |
|---|---|---|
| CRO_T001247 | AT1G06490 (0) | ATGSL07|glucan synthase-like 7; CalS7|callose synthase 7 |
| CRO_T003584 | AT1G17110 (0) | UBP15|ubiquitin-specific protease 15 |
| CRO_T006883 | AT5G53400 (2.00E-82) | BOB1|BOBBER1 |
| CRO_T016326 | AT1G48360 (2.00E-66) | zinc ion binding; nucleic acid binding; hydrolases, acting on acid anhydrides, in phosphorus-containing anhydrides |
| CRO_T031779 | AT2G40930 (0) | PDE323|PIGMENT DEFECTIVE EMBRYO 323; UBP5|ubiquitin-specific protease 5 |
| CRO_T033480 | AT1G47250 (1.00E-117) | PAF2|20S proteasome alpha subunit F2 |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TissueCFM000023 | abscisic acid biosynthesis brassinosteroids inactivation brassinosteroid metabolic process Brassinosteroid biosynthesis U12-type spliceosomal complex U2-type prespliceosome U2 snRNP catalytic step 2 spliceosome spliceosomal complex assembly brassinosteroid homeostasis protein deubiquitination Transcription_related, Transcription factor: LOB Ubiquitin_Proteasome_system, DUB: USP ubiquitin-dependent protein catabolic process | details |
| TissueCFM000057 | 2'-deoxymugineic acid phytosiderophore biosynthesis L-phenylalanine biosynthesis III (cytosolic, plants) ubiquitin-dependent protein catabolic process U12-type spliceosomal complex U2-type prespliceosome U2 snRNP catalytic step 2 spliceosome gibberellin catabolic process chiasma assembly triglyceride lipase activity C-19 gibberellin 2-beta-dioxygenase activity thiol-dependent ubiquitin-specific protease activity protein deubiquitination cellular amino acid metabolic process spliceosomal complex assembly response to light stimulus | details |
| TissueCFM000124 | NF-kappa B signaling pathway Protein_kinases_phosphatases, PPC:1.5.2: LRK10 Like Kinase (Type 1) Protein_kinases_phosphatases, PPC:1.6.2: Plant External Response Like Kinase pyruvate fermentation to lactate vindoline and vinblastine biosynthesis | details |
| TissueCFM000273 | nucleocytoplasmic transport Ubiquitin_Proteasome_system, DUB: USP apigenin glycosides biosynthesis genistin gentiobioside biosynthesis kaempferol gentiobioside biosynthesis luteolin glycosides biosynthesis myricetin gentiobioside biosynthesis unsaturated, even numbered fatty acid β-oxidation thiol-dependent ubiquitin-specific protease activity fatty acid β-oxidation II (peroxisome) sesaminol glucoside biosynthesis curcumin glucoside biosynthesis RNA transport quercetin gentiotetraside biosynthesis protein deubiquitination transferase activity, transferring hexosyl groups very long chain fatty acid biosynthesis II small GTPase mediated signal transduction ubiquitin-dependent protein catabolic process | details |
| TissueCFM000279 | Ubiquitin_Proteasome_system, DUB: USP protein deubiquitination ubiquitin-dependent protein catabolic process Transcription_related, Transcription regulator: TRAF thiol-dependent ubiquitinyl hydrolase activity thiol-dependent ubiquitin-specific protease activity ribosome biogenesis mRNA splicing, via spliceosome U2 snRNP precatalytic spliceosome U12-type spliceosomal complex Ubiquitin_Proteasome_system, E3 adaptor: BTB catalytic step 2 spliceosome Plant hormone signal transduction Spliceosome | details |
| TissueCFM000759 | Proteasome cytosolic proteasome complex nuclear proteasome complex positive regulation of RNA polymerase II transcriptional preinitiation complex assembly positive regulation of proteasomal protein catabolic process proteasome regulatory particle, base subcomplex TBP-class protein binding proteasome-activating ATPase activity ER-associated ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process phosphate acquisition positive regulation of circadian rhythm response to far red light Circadian rhythm red, far-red light phototransduction spliceosomal complex assembly U2-type prespliceosome U12-type spliceosomal complex U2 snRNP proteasome complex triglyceride lipase activity protein deubiquitination thiol-dependent ubiquitin-specific protease activity | details |
| TissueCFM000878 | hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc Ubiquitin_Proteasome_system, DUB: USP U2-type prespliceosome U12-type spliceosomal complex U2 snRNP xyloglucan metabolic process protein deubiquitination potassium ion transmembrane transport cell wall biogenesis cytoplasmic translation spliceosomal complex assembly potassium ion transmembrane transporter activity thiol-dependent ubiquitinyl hydrolase activity xyloglucan:xyloglucosyl transferase activity mRNA binding catalytic step 2 spliceosome ubiquitin-dependent protein catabolic process | details |
| TissueCFM001133 | ubiquitin-dependent protein catabolic process mitochondrial envelope mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) proteasome core complex, alpha-subunit complex protein localization to organelle interstrand cross-link repair nucleocytoplasmic transport protein transmembrane transport 1,3-beta-D-glucan synthase complex Oxidative phosphorylation hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 1,3-β-D-glucan biosynthesis apigenin glycosides biosynthesis genistin gentiobioside biosynthesis kaempferol gentiobioside biosynthesis luteolin glycosides biosynthesis myricetin gentiobioside biosynthesis unsaturated, even numbered fatty acid β-oxidation Transcription_related, Transcription regulator: SET Ubiquitin_Proteasome_system, DUB: USP (1->3)-beta-D-glucan biosynthetic process Fanconi anemia pathway nuclease activity 1,3-beta-D-glucan synthase activity thiol-dependent ubiquitin-specific protease activity protein channel activity threonine-type endopeptidase activity hydrogen ion transmembrane transporter activity fatty acid β-oxidation II (peroxisome) sesaminol glucoside biosynthesis curcumin glucoside biosynthesis Proteasome cytochrome-c oxidase activity | details |
| TissueCFM001164 | Transcription_related, Transcription regulator: MBF1 1,3-β-D-glucan biosynthesis Ubiquitin_Proteasome_system, DUB: USP 1,3-beta-D-glucan synthase complex cytosolic proteasome complex nuclear proteasome complex proteasome regulatory particle, base subcomplex hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides regulation of nucleic acid-templated transcription interstrand cross-link repair positive regulation of RNA polymerase II transcriptional preinitiation complex assembly positive regulation of proteasomal protein catabolic process thiol-dependent ubiquitin-specific protease activity nuclease activity 1,3-beta-D-glucan synthase activity proteasome-activating ATPase activity transcription coactivator activity TBP-class protein binding (1->3)-beta-D-glucan biosynthetic process protein deubiquitination ER-associated ubiquitin-dependent protein catabolic process Fanconi anemia pathway Proteasome nucleic acid phosphodiester bond hydrolysis response to stress ubiquitin-dependent protein catabolic process unfolded protein binding | details |
| TissueCFM001500 | Transcription_related, Transcription regulator: RB TGF-beta signaling pathway calcium-dependent cysteine-type endopeptidase activity alternative oxidase activity cysteine-type endopeptidase inhibitor activity regulation of DNA endoreduplication proteolysis negative regulation of cell division negative regulation of endopeptidase activity Cell cycle aerobic respiration III (alternative oxidase pathway) regulation of transcription from RNA polymerase II promoter peptidase activity Spliceosome carbohydrate binding mitochondrial inner membrane integral component of membrane respiratory chain | details |
| TissueCFM001841 | UDP-D-xylose biosynthesis vacuolar membrane regulation of plant-type hypersensitive response interstrand cross-link repair hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides UDP-glucuronate decarboxylase activity nuclease activity proteasome core complex threonine-type endopeptidase activity Fanconi anemia pathway Proteasome Amino sugar and nucleotide sugar metabolism nucleic acid phosphodiester bond hydrolysis proteolysis involved in cellular protein catabolic process S-adenosylmethionine-dependent methyltransferase activity | details |
Expression profiles
 Show details about module gene expression profiling |