TreatCFM000512's detailed annotation
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Protein: Yellow color--query protein Green color--interaction proteins. Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
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Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontolog |
|---|---|---|
| 6,7-dimethyl-8-ribityllumazine synthase activity | 0.001144801 | GO:0000906 |
| sequence-specific DNA binding | 0.001144801 | GO:0043565 |
| flavin biosynthesis I (bacteria and plants) | 0.003011068 | plantCyc |
| Riboflavin metabolism | 0.003011068 | KEGG pathway |
| nucleus | 0.003306079 | GO:0005634 |
| riboflavin synthase complex | 0.003306079 | GO:0009349 |
| regulation of transcription, DNA-templated | 0.004882419 | GO:0006355 |
| riboflavin biosynthetic process | 0.004882419 | GO:0009231 |
| Transcription_related, Transcription factor: HB | 0.013227325 | TF family |
Module member annotation
| Gene ID | Ortholog in Arabidopsis (Blast E-value) | Annotation in Arabidopsis |
|---|---|---|
| CRO_T002661 | AT5G07820 (5.00E-10) | Plant calmodulin-binding protein-related |
| CRO_T011305 | AT1G54320 (1.00E-124) | LEM3 (ligand-effect modulator 3) family protein / CDC50 family protein |
| CRO_T012412 | AT2G44050 (3.00E-67) | COS1|COI1 SUPPRESSOR1; COS1|coronatine insensitive1 suppressor |
| CRO_T015855 | AT1G04470 (0) | Protein of unknown function (DUF810) |
| CRO_T025580 | AT1G70510 (2.00E-31) | ATK1|KN 1; KNAT2|KNOTTED-like from 2 |
| CRO_T031342 | AT1G23380 (3.00E-26) | KNAT6|KNOTTED1-like homeobox gene 6 |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TreatCFM000016 | flavin biosynthesis I (bacteria and plants) riboflavin synthase complex cellular process localization mitochondrion organization 6,7-dimethyl-8-ribityllumazine synthase activity Transcription_related, Transcription factor: ARR-B riboflavin biosynthetic process | details |
| TreatCFM000018 | riboflavin synthase complex flavin biosynthesis I (bacteria and plants) Diterpenoid biosynthesis Riboflavin metabolism 6,7-dimethyl-8-ribityllumazine synthase activity mitochondrion organization gibberellin catabolic process C-19 gibberellin 2-beta-dioxygenase activity riboflavin biosynthetic process response to light stimulus Transcription_related, Transcription factor: HB Transcription_related, Transcription factor: MYB | details |
| TreatCFM000030 | flavin biosynthesis I (bacteria and plants) | details |
| TreatCFM000034 | flavin biosynthesis I (bacteria and plants) riboflavin synthase complex regulation of carbohydrate metabolic process mitochondrion organization L-methionine biosynthetic process from methylthioadenosine riboflavin biosynthetic process 6,7-dimethyl-8-ribityllumazine synthase activity eukaryotic translation initiation factor 2B complex guanyl-nucleotide exchange factor activity S-methyl-5-thioribose-1-phosphate isomerase activity Riboflavin metabolism regulation of translational initiation | details |
| TreatCFM000057 | flavin biosynthesis I (bacteria and plants) Riboflavin metabolism 6,7-dimethyl-8-ribityllumazine synthase activity riboflavin synthase complex hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc riboflavin biosynthetic process mitochondrion organization anchored component of membrane pollen tube xyloglucan metabolic process cell wall biogenesis | details |
| TreatCFM000070 | flavin biosynthesis I (bacteria and plants) riboflavin synthase complex Transcription_related, Transcription factor: ARR-B 6,7-dimethyl-8-ribityllumazine synthase activity | details |
| TreatCFM000085 | riboflavin synthase complex Transcription_related, Transcription factor: C2C2-YABBY 6,7-dimethyl-8-ribityllumazine synthase activity leucocyanidin oxygenase activity Flavonoid biosynthesis Riboflavin metabolism anthocyanin biosynthesis proanthocyanidins biosynthesis from flavanols flavin biosynthesis I (bacteria and plants) inflorescence meristem growth specification of floral organ identity fruit development abaxial cell fate specification specification of organ position mitochondrion organization anthocyanin-containing compound biosynthetic process meristem structural organization riboflavin biosynthetic process regulation of flower development L-ascorbic acid binding | details |
| TreatCFM000106 | methylation riboflavin synthase complex flavin biosynthesis I (bacteria and plants) 6,7-dimethyl-8-ribityllumazine synthase activity riboflavin biosynthetic process cellulose catabolic process Riboflavin metabolism adhesion to carbohydrates, Carbohydrate-Binding Modules: CBM57 hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc cellulase activity Starch and sucrose metabolism S-adenosylmethionine-dependent methyltransferase activity methyltransferase activity | details |
| TreatCFM000177 | flavin biosynthesis I (bacteria and plants) 6,7-dimethyl-8-ribityllumazine synthase activity riboflavin synthase complex Riboflavin metabolism riboflavin biosynthetic process regulation of stomatal opening Ribosome biogenesis in eukaryotes response to biotic stimulus drug transmembrane transport defense response | details |
| TreatCFM000378 | 6,7-dimethyl-8-ribityllumazine synthase activity ligase activity 1,2-alpha-L-fucosidase activity hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc riboflavin synthase complex flavin biosynthesis I (bacteria and plants) tetrahydrofolate biosynthesis II Folate biosynthesis Other glycan degradation Riboflavin metabolism Transcription_related, Transcription regulator: AUX/IAA riboflavin biosynthetic process mitochondrion organization folic acid-containing compound biosynthetic process auxin-activated signaling pathway | details |
| TreatCFM000418 | riboflavin synthase complex 6,7-dimethyl-8-ribityllumazine synthase activity riboflavin biosynthetic process sulfate transmembrane transport esterified suberin biosynthesis flavin biosynthesis I (bacteria and plants) Cutin, suberine and wax biosynthesis Riboflavin metabolism secondary active sulfate transmembrane transporter activity transferase activity, transferring acyl groups other than amino-acyl groups | details |
| TreatCFM000511 | Protein_kinases_phosphatases, PPC:1.14.2: Receptor Like Cytoplasmic Kinase IX photosynthetic acclimation Plant-pathogen interaction regulation of membrane potential voltage-gated potassium channel activity potassium ion transmembrane transport response to stress peptidase activity | details |
| TreatCFM000534 | riboflavin synthase complex Riboflavin metabolism 6,7-dimethyl-8-ribityllumazine synthase activity mitochondrion organization riboflavin biosynthetic process phenylpropanoid biosynthetic process methylquercetin biosynthesis polymethylated quercetin biosynthesis quercetin sulfate biosynthesis superpathway of scopolin and esculin biosynthesis flavin biosynthesis I (bacteria and plants) syringetin biosynthesis phenylpropanoids methylation (ice plant) suberin monomers biosynthesis cell part triacylglycerol degradation Phenylpropanoid biosynthesis | details |
| TreatCFM000839 | Protein_kinases_phosphatases, PPC:4.5.1.1: Male grem cell-associated kinase (mak) imidazoleglycerol-phosphate synthase activity oxo-acid-lyase activity 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity L-glutamine degradation I L-histidine biosynthesis mitochondrial proton-transporting ATP synthase complex assembly histidine biosynthetic process Biosynthesis of amino acids | details |
| TreatCFM000846 | riboflavin synthase complex flavin biosynthesis I (bacteria and plants) Riboflavin metabolism Transcription_related, Transcription factor: MIKC 6,7-dimethyl-8-ribityllumazine synthase activity riboflavin biosynthetic process | details |
| TreatCFM000847 | riboflavin synthase complex 6,7-dimethyl-8-ribityllumazine synthase activity flavin biosynthesis I (bacteria and plants) riboflavin biosynthetic process Riboflavin metabolism protein binding | details |
| TreatCFM001553 | riboflavin synthase complex Riboflavin metabolism arachidonate biosynthesis IV (8-detaturase, lower eukaryotes) sphingolipid metabolic process flavin biosynthesis I (bacteria and plants) 6,7-dimethyl-8-ribityllumazine synthase activity riboflavin biosynthetic process adhesion to carbohydrates, Carbohydrate-Binding Modules: CBM57 Protein_kinases_phosphatases, PPC:1.9.2: S Domain Kinase (Type 2) acetylglucosaminyltransferase activity formation of glycosidic bonds, GlycosylTransferases: GTnc | details |
Expression profiles
 Show details about module gene expression profiling |