TreatCFM000018's detailed annotation
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Protein: Yellow color--query protein Green color--interaction proteins. Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
| This network produced by cytoscapeweb |
Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontolog |
|---|---|---|
| riboflavin synthase complex | 0.002955301 | GO:0009349 |
| flavin biosynthesis I (bacteria and plants) | 0.003011068 | plantCyc |
| Diterpenoid biosynthesis | 0.007697963 | KEGG pathway |
| Riboflavin metabolism | 0.007697963 | KEGG pathway |
| 6,7-dimethyl-8-ribityllumazine synthase activity | 0.007710803 | GO:0000906 |
| mitochondrion organization | 0.009119644 | GO:0007005 |
| gibberellin catabolic process | 0.009119644 | GO:0045487 |
| C-19 gibberellin 2-beta-dioxygenase activity | 0.009636367 | GO:0052634 |
| riboflavin biosynthetic process | 0.010418601 | GO:0009231 |
| response to light stimulus | 0.015614051 | GO:0009416 |
| Transcription_related, Transcription factor: HB | 0.044083044 | TF family |
| Transcription_related, Transcription factor: MYB | 0.044083044 | TF family |
Module member annotation
| Gene ID | Ortholog in Arabidopsis (Blast E-value) | Annotation in Arabidopsis |
|---|---|---|
| CRO_T006338 | AT2G32460 (2.00E-60) | ATM1|MYB 1; MYB101|myb domain protein 101 |
| CRO_T010788 | AT1G80330 (8.00E-39) | ATGA3OX4|GIBBERELLIN 3-OXIDASE 4 |
| CRO_T011185 | AT5G45980 (6.00E-17) | STPL|STIMPY-LIKE; WOX8|WUSCHEL related homeobox 8; WOX9B|WUSCHEL related homeobox 9B |
| CRO_T012412 | AT2G44050 (3.00E-67) | COS1|COI1 SUPPRESSOR1; COS1|coronatine insensitive1 suppressor |
| CRO_T019726 | AT5G48670 (3.00E-18) | AGL80|AGAMOUS-like 80 |
| CRO_T022575 | AT1G59560 (4.00E-11) | DAL2|DIAP1-like protein 2; SPL1|SP1-like 1 |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TreatCFM000016 | flavin biosynthesis I (bacteria and plants) riboflavin synthase complex cellular process localization mitochondrion organization 6,7-dimethyl-8-ribityllumazine synthase activity Transcription_related, Transcription factor: ARR-B riboflavin biosynthetic process | details |
| TreatCFM000030 | flavin biosynthesis I (bacteria and plants) | details |
| TreatCFM000034 | flavin biosynthesis I (bacteria and plants) riboflavin synthase complex regulation of carbohydrate metabolic process mitochondrion organization L-methionine biosynthetic process from methylthioadenosine riboflavin biosynthetic process 6,7-dimethyl-8-ribityllumazine synthase activity eukaryotic translation initiation factor 2B complex guanyl-nucleotide exchange factor activity S-methyl-5-thioribose-1-phosphate isomerase activity Riboflavin metabolism regulation of translational initiation | details |
| TreatCFM000057 | flavin biosynthesis I (bacteria and plants) Riboflavin metabolism 6,7-dimethyl-8-ribityllumazine synthase activity riboflavin synthase complex hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc riboflavin biosynthetic process mitochondrion organization anchored component of membrane pollen tube xyloglucan metabolic process cell wall biogenesis | details |
| TreatCFM000070 | flavin biosynthesis I (bacteria and plants) riboflavin synthase complex Transcription_related, Transcription factor: ARR-B 6,7-dimethyl-8-ribityllumazine synthase activity | details |
| TreatCFM000071 | AMPK signaling pathway Fatty acid elongation Protein_kinases_phosphatases, PPC:1.13.4: Leucine Rich Repeat Kinase III very long chain fatty acid biosynthesis I very long chain fatty acid biosynthesis II | details |
| TreatCFM000085 | riboflavin synthase complex Transcription_related, Transcription factor: C2C2-YABBY 6,7-dimethyl-8-ribityllumazine synthase activity leucocyanidin oxygenase activity Flavonoid biosynthesis Riboflavin metabolism anthocyanin biosynthesis proanthocyanidins biosynthesis from flavanols flavin biosynthesis I (bacteria and plants) inflorescence meristem growth specification of floral organ identity fruit development abaxial cell fate specification specification of organ position mitochondrion organization anthocyanin-containing compound biosynthetic process meristem structural organization riboflavin biosynthetic process regulation of flower development L-ascorbic acid binding | details |
| TreatCFM000106 | methylation riboflavin synthase complex flavin biosynthesis I (bacteria and plants) 6,7-dimethyl-8-ribityllumazine synthase activity riboflavin biosynthetic process cellulose catabolic process Riboflavin metabolism adhesion to carbohydrates, Carbohydrate-Binding Modules: CBM57 hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc cellulase activity Starch and sucrose metabolism S-adenosylmethionine-dependent methyltransferase activity methyltransferase activity | details |
| TreatCFM000177 | flavin biosynthesis I (bacteria and plants) 6,7-dimethyl-8-ribityllumazine synthase activity riboflavin synthase complex Riboflavin metabolism riboflavin biosynthetic process regulation of stomatal opening Ribosome biogenesis in eukaryotes response to biotic stimulus drug transmembrane transport defense response | details |
| TreatCFM000378 | 6,7-dimethyl-8-ribityllumazine synthase activity ligase activity 1,2-alpha-L-fucosidase activity hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc riboflavin synthase complex flavin biosynthesis I (bacteria and plants) tetrahydrofolate biosynthesis II Folate biosynthesis Other glycan degradation Riboflavin metabolism Transcription_related, Transcription regulator: AUX/IAA riboflavin biosynthetic process mitochondrion organization folic acid-containing compound biosynthetic process auxin-activated signaling pathway | details |
| TreatCFM000418 | riboflavin synthase complex 6,7-dimethyl-8-ribityllumazine synthase activity riboflavin biosynthetic process sulfate transmembrane transport esterified suberin biosynthesis flavin biosynthesis I (bacteria and plants) Cutin, suberine and wax biosynthesis Riboflavin metabolism secondary active sulfate transmembrane transporter activity transferase activity, transferring acyl groups other than amino-acyl groups | details |
| TreatCFM000512 | 6,7-dimethyl-8-ribityllumazine synthase activity sequence-specific DNA binding flavin biosynthesis I (bacteria and plants) Riboflavin metabolism nucleus riboflavin synthase complex regulation of transcription, DNA-templated riboflavin biosynthetic process Transcription_related, Transcription factor: HB | details |
| TreatCFM000534 | riboflavin synthase complex Riboflavin metabolism 6,7-dimethyl-8-ribityllumazine synthase activity mitochondrion organization riboflavin biosynthetic process phenylpropanoid biosynthetic process methylquercetin biosynthesis polymethylated quercetin biosynthesis quercetin sulfate biosynthesis superpathway of scopolin and esculin biosynthesis flavin biosynthesis I (bacteria and plants) syringetin biosynthesis phenylpropanoids methylation (ice plant) suberin monomers biosynthesis cell part triacylglycerol degradation Phenylpropanoid biosynthesis | details |
| TreatCFM000846 | riboflavin synthase complex flavin biosynthesis I (bacteria and plants) Riboflavin metabolism Transcription_related, Transcription factor: MIKC 6,7-dimethyl-8-ribityllumazine synthase activity riboflavin biosynthetic process | details |
| TreatCFM000847 | riboflavin synthase complex 6,7-dimethyl-8-ribityllumazine synthase activity flavin biosynthesis I (bacteria and plants) riboflavin biosynthetic process Riboflavin metabolism protein binding | details |
| TreatCFM000992 | L-glutamine degradation I L-histidine biosynthesis sphingolipid biosynthesis (plants) proton-transporting two-sector ATPase complex, catalytic domain transferase activity, transferring pentosyl groups ATPase activity, coupled to transmembrane movement of ions, rotational mechanism cation-transporting ATPase activity mitochondrion organization ATP biosynthetic process cellular amino acid biosynthetic process hydrogen ion transmembrane transporter activity Protein_kinases_phosphatases, PPC:1.2.2: Receptor Like Cytoplasmic Kinase VII | details |
| TreatCFM001553 | riboflavin synthase complex Riboflavin metabolism arachidonate biosynthesis IV (8-detaturase, lower eukaryotes) sphingolipid metabolic process flavin biosynthesis I (bacteria and plants) 6,7-dimethyl-8-ribityllumazine synthase activity riboflavin biosynthetic process adhesion to carbohydrates, Carbohydrate-Binding Modules: CBM57 Protein_kinases_phosphatases, PPC:1.9.2: S Domain Kinase (Type 2) acetylglucosaminyltransferase activity formation of glycosidic bonds, GlycosylTransferases: GTnc | details |
Expression profiles
 Show details about module gene expression profiling |