TreatCFM001245's detailed annotation
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Protein: Yellow color--query protein Green color--interaction proteins. Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
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Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontolog |
|---|---|---|
| dTTP biosynthetic process | 0.003926845 | GO:0006235 |
| dTDP biosynthetic process | 0.003926845 | GO:0006233 |
| dUDP biosynthetic process | 0.003926845 | GO:0006227 |
| oxidoreductase activity, acting on a sulfur group of donors | 0.00519359 | GO:0016667 |
| thymidylate kinase activity | 0.00519359 | GO:0004798 |
| UDP-glycosyltransferase activity | 0.006923763 | GO:0008194 |
| DNA ligation involved in DNA repair | 0.007850208 | GO:0051103 |
| protein ADP-ribosylation | 0.007850208 | GO:0006471 |
| lagging strand elongation | 0.007850208 | GO:0006273 |
| uridylate kinase activity | 0.00830606 | GO:0009041 |
| NAD+ ADP-ribosyltransferase activity | 0.00830606 | GO:0003950 |
| DNA ligase (ATP) activity | 0.008650868 | GO:0003910 |
| Base excision repair | 0.009286528 | KEGG pathway |
| Pyrimidine metabolism | 0.009286528 | KEGG pathway |
| crocetin esters biosynthesis | 0.009892553 | plantCyc |
| pyrimidine deoxyribonucleotide phosphorylation | 0.009892553 | plantCyc |
| pyrimidine deoxyribonucleotides de novo biosynthesis I | 0.009892553 | plantCyc |
| pyrimidine deoxyribonucleotides de novo biosynthesis II | 0.009892553 | plantCyc |
| superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli) | 0.009892553 | plantCyc |
| transferase activity, transferring hexosyl groups | 0.02442805 | GO:0016758 |
| triacylglycerol degradation | 0.03154742 | plantCyc |
| Transcription_related, Transcription factor: C2H2 | 0.041260108 | TF family |
| NAD binding | 0.042644996 | GO:0051287 |
| single-organism metabolic process | 0.042759717 | GO:0044710 |
Module member annotation
| Gene ID | Ortholog in Arabidopsis (Blast E-value) | Annotation in Arabidopsis |
|---|---|---|
| CRO_T008992 | AT5G12890 (3.00E-130) | UDP-Glycosyltransferase superfamily protein |
| CRO_T009346 | AT1G18460 (0) | alpha/beta-Hydrolases superfamily protein |
| CRO_T011864 | AT2G31320 (0) | PARP1|POLY(ADP-RIBOSE) POLYMERASE 1 |
| CRO_T012147 | AT5G59440 (9.00E-86) | ATTMPK.1|THYMIDYLATE KINASE.1; ATTMPK.2|THYMIDYLATE KINASE.2; ZEU1|ZEUS1 |
| CRO_T031020 | AT1G49900 (4.00E-19) | C2H2 type zinc finger transcription factor family |
| CRO_T031063 | - | - |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TreatCFM000052 | details | |
| TreatCFM000155 | dTTP biosynthetic process dTDP biosynthetic process dUDP biosynthetic process positive regulation of autophagy response to extracellular stimulus thymidylate kinase activity organ morphogenesis pyrimidine deoxyribonucleotide phosphorylation pyrimidine deoxyribonucleotides de novo biosynthesis II superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli) pyrimidine deoxyribonucleotides de novo biosynthesis I regulation of root development lateral root development reactive oxygen species metabolic process endoplasmic reticulum unfolded protein response fruit development RNA biosynthetic process defense response to fungus, incompatible interaction uridylate kinase activity endoplasmic reticulum heterotrimeric G-protein complex negative regulation of abscisic acid-activated signaling pathway Cul4-RING E3 ubiquitin ligase complex Transcription_related, Transcription factor: AP2 Transcription_related, Transcription regulator: mTERF histone acetyltransferase activity histone acetylation Pyrimidine metabolism Ras signaling pathway jasmonic acid mediated signaling pathway response to ethylene phosphoprotein phosphatase activity DNA-directed RNA polymerase activity | details |
| TreatCFM000185 | auxin biosynthetic process negative regulation of ethylene biosynthetic process lagging strand elongation copper ion export DNA ligation involved in DNA repair response to water shade avoidance negative regulation of indoleacetic acid biosynthetic process via tryptophan copper ion transport protein ADP-ribosylation regulation of transcription, DNA-templated | details |
| TreatCFM000327 | nucleoside metabolic process quercetin 7-O-glucosyltransferase activity quercetin 3-O-glucosyltransferase activity dTDP biosynthetic process flavonoid biosynthetic process dTTP biosynthetic process dUDP biosynthetic process flavonoid glucuronidation thymidylate kinase activity catalytic activity uridylate kinase activity apigeninidin 5-O-glucoside biosynthesis luteolinidin 5-O-glucoside biosynthesis Pyrimidine metabolism intracellular membrane-bounded organelle integral component of membrane pyrimidine deoxyribonucleotide phosphorylation pyrimidine deoxyribonucleotides de novo biosynthesis II superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli) formation of glycosidic bonds, GlycosylTransferases: GTnc pyrimidine deoxyribonucleotides de novo biosynthesis I cytokinin-O-glucosides biosynthesis chloroplast outer membrane chloroplast organization | details |
| TreatCFM000618 | dUDP biosynthetic process dTDP biosynthetic process dTTP biosynthetic process thymidylate kinase activity ethanolamine-phosphate cytidylyltransferase activity | details |
| TreatCFM001002 | sulfite oxidation IV ceramide degradation Protein_kinases_phosphatases, PPC:1.2.1: Receptor Like Cytoplasmic Kinase VIII formation of glycosidic bonds, GlycosylTransferases: GTnc starch metabolic process sphingolipid catabolic process carboxylic acid metabolic process seed maturation sucrose metabolic process Sphingolipid metabolism Sulfur metabolism sucrose synthase activity carboxy-lyase activity triacylglycerol degradation single-organism metabolic process Plant-pathogen interaction lipid metabolic process Starch and sucrose metabolism | details |
| TreatCFM001152 | saccharopine dehydrogenase (NADP+, L-lysine-forming) activity UDP-glycosyltransferase activity 3-hydroxyacyl-CoA dehydrogenase activity Valine, leucine and isoleucine degradation L-lysine catabolic process leucine catabolic process Lysine degradation cobalt ion binding fatty acid metabolic process crocetin esters biosynthesis L-leucine degradation I unsaturated, even numbered fatty acid β-oxidation fatty acid β-oxidation II (peroxisome) Fatty acid metabolism transferase activity, transferring hexosyl groups triacylglycerol degradation very long chain fatty acid biosynthesis II formation of glycosidic bonds, GlycosylTransferases: GTnc lipid metabolic process flavonoid biosynthetic process flavonoid glucuronidation oxidation-reduction process | details |
| TreatCFM001153 | 3-hydroxyacyl-CoA dehydrogenase activity unsaturated, even numbered fatty acid β-oxidation fatty acid β-oxidation II (peroxisome) fatty acid metabolic process Fatty acid metabolism very long chain fatty acid biosynthesis II Valine, leucine and isoleucine degradation innate immune response protein monoubiquitination histone ubiquitination cytidine to uridine editing leucine catabolic process L-leucine degradation I reproductive structure development SCF-dependent proteasomal ubiquitin-dependent protein catabolic process post-embryonic development jasmonic acid biosynthesis cobalt ion binding SCF ubiquitin ligase complex | details |
| TreatCFM001331 | 3-deoxy-8-phosphooctulonate synthase activity thymidylate kinase activity response to extracellular stimulus dUDP biosynthetic process dTTP biosynthetic process dTDP biosynthetic process organ morphogenesis regulation of root development reactive oxygen species metabolic process lateral root development CMP-3-deoxy-D-manno-octulosonate biosynthesis pyrimidine deoxyribonucleotide phosphorylation pyrimidine deoxyribonucleotides de novo biosynthesis II superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli) fruit development endoplasmic reticulum unfolded protein response uridylate kinase activity defense response to fungus, incompatible interaction pyrimidine deoxyribonucleotides de novo biosynthesis I endoplasmic reticulum heterotrimeric G-protein complex negative regulation of abscisic acid-activated signaling pathway histone acetyltransferase activity Cul4-RING E3 ubiquitin ligase complex histone acetylation Transcription_related, Transcription regulator: mTERF Lipopolysaccharide biosynthesis jasmonic acid mediated signaling pathway response to ethylene Ras signaling pathway Pyrimidine metabolism biosynthetic process helicase activity RNA degradation | details |
| TreatCFM001371 | mevalonate pathway I DNA ligation involved in DNA repair lagging strand elongation protein ADP-ribosylation regulation of intracellular pH ATP biosynthetic process DNA ligase (ATP) activity NAD+ ADP-ribosyltransferase activity hydrogen-exporting ATPase activity, phosphorylative mechanism acetyl-CoA C-acetyltransferase activity Base excision repair protein catabolic process hydrogen ion transmembrane transport aspartic-type endopeptidase activity | details |
| TreatCFM001522 | Base excision repair DNA ligation involved in DNA repair protein ADP-ribosylation lagging strand elongation anion transmembrane transport DNA ligase (ATP) activity inorganic phosphate transmembrane transporter activity NAD+ ADP-ribosyltransferase activity response to stimulus | details |
Expression profiles
 Show details about module gene expression profiling |