TissueCFM001167's detailed annotation
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Protein: Yellow color--query protein Green color--interaction proteins. Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
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Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontolog |
|---|---|---|
| histone H3-K4 methylation | 0.002437583 | GO:0051568 |
| histone H3-K36 methylation | 0.002437583 | GO:0010452 |
| negative regulation of flower development | 0.002924235 | GO:0009910 |
| Cul4-RING E3 ubiquitin ligase complex | 0.005847606 | GO:0080008 |
| RNA degradation | 0.013051924 | KEGG pathway |
Module member annotation
| Gene ID | Ortholog in Arabidopsis (Blast E-value) | Annotation in Arabidopsis |
|---|---|---|
| CRO_T001946 | AT5G61990 (1.00E-48) | Pentatricopeptide repeat (PPR) superfamily protein |
| CRO_T005977 | AT3G49660 (1.00E-12) | WDR5a|human WDR5 (WD40 repeat) homolog a |
| CRO_T007069 | AT4G17720 (4.00E-85) | RNA-binding (RRM/RBD/RNP motifs) family protein |
| CRO_T012300 | AT3G24000 (0) | Tetratricopeptide repeat (TPR)-like superfamily protein |
| CRO_T014842 | AT5G36740 (2.00E-104) | Acyl-CoA N-acyltransferase with RING/FYVE/PHD-type zinc finger protein |
| CRO_T029965 | AT1G03070 (2.00E-64) | LFG4|LIFEGUARD 4 |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TissueCFM000271 | carboxypeptidase activity histone H3-K36 methylation histone H3-K4 methylation negative regulation of flower development | details |
| TissueCFM000326 | Ubiquitin_Proteasome_system, E3 adaptor: DWD protein targeting to peroxisome histone H3-K36 methylation histone H3-K4 methylation negative regulation of flower development 1-phosphatidylinositol-4-phosphate 5-kinase activity 3-phosphoinositide biosynthesis D-myo-inositol (1,4,5)-trisphosphate biosynthesis phosphatidylinositol phosphorylation Cul4-RING E3 ubiquitin ligase complex spliceosomal complex mRNA splicing, via spliceosome Inositol phosphate metabolism Peroxisome RNA degradation | details |
| TissueCFM000790 | formation of glycosidic bonds, GlycosylTransferases: GTnc Calcium signaling pathway voltage-gated anion channel activity threonine-type endopeptidase activity mitochondrial outer membrane proteasome core complex Proteasome regulation of anion transmembrane transport anion transport | details |
| TissueCFM000947 | inosine-5'-phosphate biosynthesis II adenine biosynthetic process isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway maltose metabolic process isopentenyl diphosphate biosynthetic process, mevalonate pathway alpha-1,4-glucosidase activity phosphoribosylaminoimidazole carboxylase activity poly(G) binding phosphoribosylaminoimidazolesuccinocarboxamide synthase activity maltose alpha-glucosidase activity DNA topoisomerase activity 'de novo' IMP biosynthetic process root development translational elongation regulation of catalytic activity sterol metabolic process translation elongation factor activity | details |
| TissueCFM001209 | cytoskeleton-dependent intracellular transport regulation of microtubule-based process protein localization activation of GTPase activity regulation of vesicle fusion Rab GTPase binding ATP-dependent microtubule motor activity, plus-end-directed GTPase activator activity mRNA splicing, via spliceosome microtubule-based movement root development Spliceosome microtubule kinesin complex spliceosomal complex endomembrane system microtubule binding | details |
| TissueCFM001265 | Protein_kinases_phosphatases, PPC:5.1.1: Other Kinase Transcription_related, Transcription regulator: mTERF plasma membrane respiratory chain complex I protein kinase CK2 complex aerobic respiration I (cytochrome c) aerobic respiration III (alternative oxidase pathway) NAD/NADH phosphorylation and dephosphorylation regulation of protein kinase activity stem cell fate determination mitochondrial electron transport, NADH to ubiquinone cellular calcium ion homeostasis meristem maintenance pollen maturation cation transmembrane transport nucleic acid metabolic process cellular response to phosphate starvation pollen germination nucleobase-containing compound metabolic process cellular macromolecule metabolic process mitochondrial respiratory chain complex I hydrogen-translocating pyrophosphatase activity inorganic diphosphatase activity protein kinase regulator activity cation-transporting ATPase activity | details |
| TissueCFM001319 | nucleic acid binding Ubiquitin_Proteasome_system, E3 adaptor: DDB1 5'-3' exoribonuclease activity RIG-I-like receptor signaling pathway stem cell fate determination meristem maintenance cellular calcium ion homeostasis pollen maturation cellular response to phosphate starvation RNA phosphodiester bond hydrolysis, exonucleolytic pollen germination cation transmembrane transport cation-transporting ATPase activity RNA secondary structure unwinding mRNA splicing, via spliceosome Ribosome biogenesis in eukaryotes | details |
| TissueCFM001388 | 1,3-β-D-glucan biosynthesis Transcription_related, Transcription regulator: SET Proteasome calcium-dependent cysteine-type endopeptidase activity threonine-type endopeptidase activity 1,3-beta-D-glucan synthase activity defense response to fungus, incompatible interaction (1->3)-beta-D-glucan biosynthetic process proteolysis involved in cellular protein catabolic process 1,3-beta-D-glucan synthase complex proteasome core complex | details |
| TissueCFM001443 | 1,3-β-D-glucan biosynthesis Transcription_related, Transcription factor: HSF nuclear envelope reassembly membrane fusion 1,3-beta-D-glucan synthase complex transmembrane receptor protein kinase activity 1,3-beta-D-glucan synthase activity ubiquitin binding Golgi organization (1->3)-beta-D-glucan biosynthetic process | details |
| TissueCFM001497 | positive regulation of translational elongation histone H3-K36 methylation translational frameshifting positive regulation of translational termination histone H3-K4 methylation negative regulation of flower development Proteasome RNA degradation Cul4-RING E3 ubiquitin ligase complex proteasome core complex, alpha-subunit complex Protein_kinases_phosphatases, PPC:2.1.4: GmPK6/AtMRK1 Family translational initiation formation of glycosidic bonds, GlycosylTransferases: GTnc ubiquitin-dependent protein catabolic process translation elongation factor activity threonine-type endopeptidase activity ribosome binding | details |
| TissueCFM001511 | formation of glycosidic bonds, GlycosylTransferases: GTnc Protein_kinases_phosphatases, PPC:5.1.1: Other Kinase plasma membrane respiratory chain complex I mitochondrial respiratory chain complex I mitochondrial electron transport, NADH to ubiquinone aerobic respiration I (cytochrome c) aerobic respiration III (alternative oxidase pathway) NAD/NADH phosphorylation and dephosphorylation 2 iron, 2 sulfur cluster binding zinc ion binding response to oxidative stress NADH dehydrogenase (ubiquinone) activity | details |
| TissueCFM001512 | 1,3-β-D-glucan biosynthesis formation of glycosidic bonds, GlycosylTransferases: GTnc nuclear pore inner ring microtubule organizing center cellular component assembly cell cycle process microtubule cytoskeleton organization double-strand break repair via homologous recombination (1->3)-beta-D-glucan biosynthetic process nuclear pore organization protein import into nucleus, docking regulation of ARF protein signal transduction 1,3-beta-D-glucan synthase complex ARF guanyl-nucleotide exchange factor activity 1,3-beta-D-glucan synthase activity structural constituent of nuclear pore Transcription_related, Transcription regulator: SNF2 positive regulation of GTPase activity RNA transport organic cyclic compound binding heterocyclic compound binding | details |
| TissueCFM001521 | Inositol phosphate metabolism 3-phosphoinositide biosynthesis D-myo-inositol (1,4,5)-trisphosphate biosynthesis Transcription_related, Transcription factor: HSF ureidoglycolate hydrolase activity 1-phosphatidylinositol-4-phosphate 5-kinase activity formation of glycosidic bonds, GlycosylTransferases: GTnc | details |
| TissueCFM001572 | Protein_kinases_phosphatases, PPC:1.4.2: Tousled like kinase phosphatidylinositol-4,5-bisphosphate binding phosphatidic acid binding phosphatidylinositol-4-phosphate binding actin filament binding 1-phosphatidylinositol 4-kinase activity beta-tubulin binding 3-phosphoinositide biosynthesis D-myo-inositol (1,4,5)-trisphosphate biosynthesis histone H3-K36 methylation histone H3-K4 methylation post-chaperonin tubulin folding pathway phosphatidylinositol-mediated signaling tubulin complex assembly negative regulation of flower development solute:proton antiporter activity perinuclear region of cytoplasm microtubule cytoskeleton organization threonine-type endopeptidase activity Cul4-RING E3 ubiquitin ligase complex proteasome core complex, alpha-subunit complex protein phosphorylation phosphatidylinositol phosphorylation GTPase activator activity Inositol phosphate metabolism Proteasome RNA degradation positive regulation of GTPase activity cytoplasm S-adenosylmethionine-dependent methyltransferase activity ubiquitin-dependent protein catabolic process hydrogen ion transmembrane transport | details |
| TissueCFM001627 | plasma membrane respiratory chain complex I mitochondrial electron transport, NADH to ubiquinone cellular response to nitrogen starvation intracellular distribution of mitochondria Transcription_related, Transcription regulator: DDT autophagy mitochondrial respiratory chain complex I Apelin signaling pathway aerobic respiration I (cytochrome c) aerobic respiration III (alternative oxidase pathway) NAD/NADH phosphorylation and dephosphorylation Transcription_related, Transcription regulator: SNF2 response to oxidative stress | details |
| TissueCFM001677 | RNA degradation seleno-amino acid biosynthesis histone H3-K36 methylation translational frameshifting positive regulation of translational termination positive regulation of translational elongation 'de novo' L-methionine biosynthetic process histone H3-K4 methylation negative regulation of flower development L-cysteine desulfhydrase activity cystathionine beta-lyase activity L-cystine L-cysteine-lyase (deaminating) cystathionine gamma-lyase activity proteasome core complex, alpha-subunit complex Cul4-RING E3 ubiquitin ligase complex Transcription_related, Transcription regulator: DDT Proteasome Biosynthesis of amino acids Transcription_related, Transcription regulator: PHD Transcription_related, Transcription regulator: SNF2 threonine-type endopeptidase activity ribosome binding poly(A) RNA binding | details |
| TissueCFM001838 | formation of glycosidic bonds, GlycosylTransferases: GTnc 1,3-β-D-glucan biosynthesis (1->3)-beta-D-glucan biosynthetic process Ubiquitin_Proteasome_system, E2: UBC 1,3-beta-D-glucan synthase complex protein ubiquitination 1,3-beta-D-glucan synthase activity Protein processing in endoplasmic reticulum | details |
Expression profiles
 Show details about module gene expression profiling |