TissueCFM000326's detailed annotation
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Protein: Yellow color--query protein Green color--interaction proteins. Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
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Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontolog |
|---|---|---|
| Ubiquitin_Proteasome_system, E3 adaptor: DWD | 0.000528847 | ubs family |
| protein targeting to peroxisome | 0.003909574 | GO:0006625 |
| histone H3-K36 methylation | 0.003909574 | GO:0010452 |
| histone H3-K4 methylation | 0.00434333 | GO:0051568 |
| negative regulation of flower development | 0.005861762 | GO:0009910 |
| 1-phosphatidylinositol-4-phosphate 5-kinase activity | 0.008863283 | GO:0016308 |
| 3-phosphoinositide biosynthesis | 0.009551151 | plantCyc |
| D-myo-inositol (1,4,5)-trisphosphate biosynthesis | 0.009551151 | plantCyc |
| phosphatidylinositol phosphorylation | 0.012491241 | GO:0046854 |
| Cul4-RING E3 ubiquitin ligase complex | 0.015493564 | GO:0080008 |
| spliceosomal complex | 0.015493564 | GO:0005681 |
| mRNA splicing, via spliceosome | 0.021213241 | GO:0000398 |
| Inositol phosphate metabolism | 0.036076941 | KEGG pathway |
| Peroxisome | 0.036076941 | KEGG pathway |
| RNA degradation | 0.036255345 | KEGG pathway |
Module member annotation
| Gene ID | Ortholog in Arabidopsis (Blast E-value) | Annotation in Arabidopsis |
|---|---|---|
| CRO_T001687 | AT4G03120 (2.00E-22) | C2H2 and C2HC zinc fingers superfamily protein |
| CRO_T005977 | AT3G49660 (1.00E-12) | WDR5a|human WDR5 (WD40 repeat) homolog a |
| CRO_T012919 | AT2G05720 (4.00E-14) | Transducin/WD40 repeat-like superfamily protein |
| CRO_T014842 | AT5G36740 (2.00E-104) | Acyl-CoA N-acyltransferase with RING/FYVE/PHD-type zinc finger protein |
| CRO_T017055 | AT1G21980 (0) | ATPIP5K1|phosphatidylinositol-4-phosphate 5-kinase 1 |
| CRO_T018786 | - | - |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TissueCFM000264 | NatA complex N-terminal peptidyl-serine acetylation N-terminal peptidyl-glutamic acid acetylation internal protein amino acid acetylation peptide-serine-N-acetyltransferase activity peptide-glutamate-N-acetyltransferase activity Transcription_related, Transcription regulator: GNAT cytosolic ribosome RNA binding ARF guanyl-nucleotide exchange factor activity spliceosomal complex regulation of ARF protein signal transduction ribonuclease III activity MicroRNAs in cancer RNA phosphodiester bond hydrolysis, endonucleolytic positive regulation of GTPase activity RNA processing mRNA splicing, via spliceosome RNA degradation | details |
| TissueCFM000271 | carboxypeptidase activity histone H3-K36 methylation histone H3-K4 methylation negative regulation of flower development | details |
| TissueCFM000458 | peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity recognition of pollen Protein_kinases_phosphatases, PPC:1.9.2: S Domain Kinase (Type 2) mRNA splicing, via spliceosome Spliceosome spliceosomal complex | details |
| TissueCFM000498 | glucose and glucose-1-phosphate degradation mannitol biosynthesis L-ascorbate biosynthesis I (L-galactose pathway) protein targeting to peroxisome protein import into chloroplast stroma ABC transporters Peroxisome integral component of mitochondrial inner membrane mitochondrial inner membrane presequence translocase complex protein import into mitochondrial matrix Transcription_related, Transcription factor: SBP protein channel activity | details |
| TissueCFM001066 | N-terminal peptidyl-glutamic acid acetylation positive regulation of transcription from RNA polymerase I promoter internal protein amino acid acetylation N-terminal peptidyl-serine acetylation N-terminal peptidyl-methionine acetylation t-UTP complex NatB complex NatA complex peptide-glutamate-N-acetyltransferase activity peptide-serine-N-acetyltransferase activity cytosolic ribosome 90S preribosome Transcription_related, Transcription regulator: GNAT spliceosomal complex peptide alpha-N-acetyltransferase activity snoRNA binding hydroquinone:oxygen oxidoreductase activity lignin catabolic process Autophagy - yeast maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) mRNA splicing, via spliceosome small-subunit processome Ribosome biogenesis in eukaryotes | details |
| TissueCFM001067 | N-terminal peptidyl-glutamic acid acetylation internal protein amino acid acetylation N-terminal peptidyl-serine acetylation peptide-glutamate-N-acetyltransferase activity peptide-serine-N-acetyltransferase activity NatA complex cytosolic ribosome spliceosomal complex Transcription_related, Transcription regulator: GNAT mRNA splicing, via spliceosome Spliceosome | details |
| TissueCFM001167 | histone H3-K4 methylation histone H3-K36 methylation negative regulation of flower development Cul4-RING E3 ubiquitin ligase complex RNA degradation | details |
| TissueCFM001199 | D-myo-inositol (1,4,5)-trisphosphate degradation Transcription_related, Transcription factor: SBP Transcription_related, Transcription regulator: GNAT peptide-serine-N-acetyltransferase activity peptide-glutamate-N-acetyltransferase activity long-day photoperiodism N-terminal peptidyl-serine acetylation N-terminal peptidyl-glutamic acid acetylation stem cell fate determination internal protein amino acid acetylation meristem maintenance cellular calcium ion homeostasis nuclear-transcribed mRNA catabolic process, nonsense-mediated decay pollen maturation NatA complex sugar mediated signaling pathway phosphatidylinositol dephosphorylation cellular response to phosphate starvation pollen germination response to wounding nucleic acid metabolic process cellular macromolecule metabolic process cation transmembrane transport salicylic acid mediated signaling pathway jasmonic acid mediated signaling pathway cation-transporting ATPase activity | details |
| TissueCFM001209 | cytoskeleton-dependent intracellular transport regulation of microtubule-based process protein localization activation of GTPase activity regulation of vesicle fusion Rab GTPase binding ATP-dependent microtubule motor activity, plus-end-directed GTPase activator activity mRNA splicing, via spliceosome microtubule-based movement root development Spliceosome microtubule kinesin complex spliceosomal complex endomembrane system microtubule binding | details |
| TissueCFM001217 | Peroxisome phospholipid transport polarity specification of adaxial/abaxial axis determination of bilateral symmetry xylem development radial pattern formation protein targeting to peroxisome meristem initiation phosphatidic acid transporter activity xylem and phloem pattern formation benzoate biosynthesis I (CoA-dependent, β-oxidative) mitochondrial intermembrane space cell differentiation flower development cellular protein metabolic process transcription regulatory region DNA binding cysteine-type peptidase activity Transcription_related, Transcription factor: ARF Ubiquitin_Proteasome_system, DUB: USP | details |
| TissueCFM001296 | phosphatidic acid transporter activity photoreceptor activity phospholipid transport protein-tetrapyrrole linkage detection of visible light mitochondrial intermembrane space red, far-red light phototransduction phosphorelay sensor kinase activity spliceosomal complex Circadian rhythm - plant phosphorelay signal transduction system signal transduction by protein phosphorylation protein-chromophore linkage mRNA splicing, via spliceosome protein homodimerization activity | details |
| TissueCFM001371 | actin binding N-terminal peptidyl-glutamic acid acetylation internal protein amino acid acetylation N-terminal peptidyl-serine acetylation peptide-serine-N-acetyltransferase activity peptide-glutamate-N-acetyltransferase activity NatA complex phosphatidylinositol-mediated signaling cytoskeleton organization Transcription_related, Transcription regulator: GNAT Ubiquitin_Proteasome_system, DUB: USP 1-phosphatidylinositol 4-kinase activity DNA topoisomerase type I activity 3-phosphoinositide biosynthesis D-myo-inositol (1,4,5)-trisphosphate biosynthesis motor activity myosin complex cytosolic ribosome spliceosomal complex phosphatidylinositol phosphorylation single-organism process mRNA splicing, via spliceosome Inositol phosphate metabolism | details |
| TissueCFM001388 | 1,3-β-D-glucan biosynthesis Transcription_related, Transcription regulator: SET Proteasome calcium-dependent cysteine-type endopeptidase activity threonine-type endopeptidase activity 1,3-beta-D-glucan synthase activity defense response to fungus, incompatible interaction (1->3)-beta-D-glucan biosynthetic process proteolysis involved in cellular protein catabolic process 1,3-beta-D-glucan synthase complex proteasome core complex | details |
| TissueCFM001443 | 1,3-β-D-glucan biosynthesis Transcription_related, Transcription factor: HSF nuclear envelope reassembly membrane fusion 1,3-beta-D-glucan synthase complex transmembrane receptor protein kinase activity 1,3-beta-D-glucan synthase activity ubiquitin binding Golgi organization (1->3)-beta-D-glucan biosynthetic process | details |
| TissueCFM001497 | positive regulation of translational elongation histone H3-K36 methylation translational frameshifting positive regulation of translational termination histone H3-K4 methylation negative regulation of flower development Proteasome RNA degradation Cul4-RING E3 ubiquitin ligase complex proteasome core complex, alpha-subunit complex Protein_kinases_phosphatases, PPC:2.1.4: GmPK6/AtMRK1 Family translational initiation formation of glycosidic bonds, GlycosylTransferases: GTnc ubiquitin-dependent protein catabolic process translation elongation factor activity threonine-type endopeptidase activity ribosome binding | details |
| TissueCFM001521 | Inositol phosphate metabolism 3-phosphoinositide biosynthesis D-myo-inositol (1,4,5)-trisphosphate biosynthesis Transcription_related, Transcription factor: HSF ureidoglycolate hydrolase activity 1-phosphatidylinositol-4-phosphate 5-kinase activity formation of glycosidic bonds, GlycosylTransferases: GTnc | details |
| TissueCFM001572 | Protein_kinases_phosphatases, PPC:1.4.2: Tousled like kinase phosphatidylinositol-4,5-bisphosphate binding phosphatidic acid binding phosphatidylinositol-4-phosphate binding actin filament binding 1-phosphatidylinositol 4-kinase activity beta-tubulin binding 3-phosphoinositide biosynthesis D-myo-inositol (1,4,5)-trisphosphate biosynthesis histone H3-K36 methylation histone H3-K4 methylation post-chaperonin tubulin folding pathway phosphatidylinositol-mediated signaling tubulin complex assembly negative regulation of flower development solute:proton antiporter activity perinuclear region of cytoplasm microtubule cytoskeleton organization threonine-type endopeptidase activity Cul4-RING E3 ubiquitin ligase complex proteasome core complex, alpha-subunit complex protein phosphorylation phosphatidylinositol phosphorylation GTPase activator activity Inositol phosphate metabolism Proteasome RNA degradation positive regulation of GTPase activity cytoplasm S-adenosylmethionine-dependent methyltransferase activity ubiquitin-dependent protein catabolic process hydrogen ion transmembrane transport | details |
| TissueCFM001601 | peptide-serine-N-acetyltransferase activity peptide-glutamate-N-acetyltransferase activity N-terminal peptidyl-glutamic acid acetylation internal protein amino acid acetylation N-terminal peptidyl-serine acetylation cellulose biosynthesis NatA complex Autophagy - yeast cytosolic ribosome spliceosomal complex plasma membrane zinc ion binding cellulose synthase (UDP-forming) activity recognition of pollen formation of glycosidic bonds, GlycosylTransferases: GTnc Protein_kinases_phosphatases, PPC:1.9.2: S Domain Kinase (Type 2) Transcription_related, Transcription regulator: GNAT cellulose biosynthetic process mRNA splicing, via spliceosome Spliceosome | details |
| TissueCFM001673 | N-terminal peptidyl-serine acetylation N-terminal peptidyl-glutamic acid acetylation internal protein amino acid acetylation Transcription_related, Transcription regulator: GNAT long-day photoperiodism peptide-serine-N-acetyltransferase activity peptide-glutamate-N-acetyltransferase activity NatA complex nuclear-transcribed mRNA catabolic process, nonsense-mediated decay G-protein beta/gamma-subunit complex binding G-protein coupled receptor signaling pathway sugar mediated signaling pathway response to wounding salicylic acid mediated signaling pathway cytoplasmic mRNA processing body cytosolic ribosome spliceosomal complex jasmonic acid mediated signaling pathway mRNA splicing, via spliceosome defense response to bacterium signal transducer activity | details |
| TissueCFM001677 | RNA degradation seleno-amino acid biosynthesis histone H3-K36 methylation translational frameshifting positive regulation of translational termination positive regulation of translational elongation 'de novo' L-methionine biosynthetic process histone H3-K4 methylation negative regulation of flower development L-cysteine desulfhydrase activity cystathionine beta-lyase activity L-cystine L-cysteine-lyase (deaminating) cystathionine gamma-lyase activity proteasome core complex, alpha-subunit complex Cul4-RING E3 ubiquitin ligase complex Transcription_related, Transcription regulator: DDT Proteasome Biosynthesis of amino acids Transcription_related, Transcription regulator: PHD Transcription_related, Transcription regulator: SNF2 threonine-type endopeptidase activity ribosome binding poly(A) RNA binding | details |
Expression profiles
 Show details about module gene expression profiling |