TissueCFM001708's detailed annotation
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Protein: Yellow color--query protein Green color--interaction proteins. Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
| This network produced by cytoscapeweb |
Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontolog |
|---|---|---|
| inosine nucleosidase activity | 0.002955301 | GO:0047724 |
| protein targeting to ER | 0.003909574 | GO:0045047 |
| inosine catabolic process | 0.003909574 | GO:0006148 |
| signal peptidase complex | 0.004432624 | GO:0005787 |
| adenine and adenosine salvage II | 0.008089153 | plantCyc |
| guanosine nucleotides degradation I | 0.008089153 | plantCyc |
| pyrimidine ribonucleosides salvage II | 0.008089153 | plantCyc |
| pyrimidine salvage pathway | 0.008089153 | plantCyc |
| signal peptide processing | 0.011285984 | GO:0006465 |
| adenosine nucleotides degradation I | 0.011314777 | plantCyc |
| DNA replication | 0.012723584 | KEGG pathway |
| Protein export | 0.012723584 | KEGG pathway |
| DNA recombination | 0.016263435 | GO:0006310 |
| UDP-glucosyltransferase activity | 0.019911468 | GO:0035251 |
| DNA repair | 0.028106773 | GO:0006281 |
| peptidase activity | 0.031379145 | GO:0008233 |
Module member annotation
| Gene ID | Ortholog in Arabidopsis (Blast E-value) | Annotation in Arabidopsis |
|---|---|---|
| CRO_T006964 | AT3G02920 (2.00E-55) | ATRPA32B; RPA32B|Replication protein A, subunit RPA32 |
| CRO_T020499 | AT5G55960 (0) | unknown protein |
| CRO_T025122 | AT2G34920 (0.0000001) | EDA18|embryo sac development arrest 18 |
| CRO_T026181 | AT2G39960 (3.00E-51) | Microsomal signal peptidase 25 kDa subunit (SPC25) |
| CRO_T028488 | AT1G05620 (2.00E-128) | NSH2|nucleoside hydrolase 2; URH2|uridine-ribohydrolase 2 |
| CRO_T033787 | AT1G55340 (1.00E-44) | Protein of unknown function (DUF1639) |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TissueCFM000554 | molybdenum cofactor biosynthesis Transcriptional misregulation in cancers nucleic acid binding nucleotide binding carbohydrate metabolic process | details |
| TissueCFM000597 | Transcription_related, Transcription regulator: LIM SREBP signaling pathway endoplasmic reticulum signal peptide binding cholesterol binding U2-type catalytic step 1 spliceosome cytoskeleton organization SRP-dependent cotranslational protein targeting to membrane signal recognition particle, endoplasmic reticulum targeting ER-associated ubiquitin-dependent protein catabolic process 7S RNA binding Protein export mRNA splicing, via spliceosome Endocytosis catalytic step 2 spliceosome small GTPase mediated signal transduction | details |
| TissueCFM000674 | cortical microtubule organization chaperone-mediated protein complex assembly prefoldin complex mRNA surveillance pathway translational initiation chaperone binding protein folding | details |
| TissueCFM000675 | nucleic acid binding histidine phosphotransfer kinase activity nucleotide binding protein histidine kinase binding Transcriptional misregulation in cancers cytokinin-activated signaling pathway phosphorelay signal transduction system mRNA surveillance pathway | details |
| TissueCFM001127 | cholesterol binding thiol oxidase activity SREBP signaling pathway Calcium signaling pathway voltage-gated anion channel activity ER-associated ubiquitin-dependent protein catabolic process regulation of anion transmembrane transport stromule mitochondrial outer membrane chloroplast outer membrane Endocytosis ubiquitin protein ligase binding identical protein binding | details |
| TissueCFM001205 | Ubiquitin_Proteasome_system, DUB: UCH thiol-dependent ubiquitin-specific protease activity shoot system morphogenesis Transcription_related, Transcription factor: HSF protein deubiquitination leaf development ubiquitin-dependent protein catabolic process | details |
| TissueCFM001338 | Betalain biosynthesis Tyrosine metabolism inosine nucleosidase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen cellular aromatic compound metabolic process negative regulation of endopeptidase activity inosine catabolic process adenine and adenosine salvage II guanosine nucleotides degradation I pyrimidine ribonucleosides salvage II pyrimidine salvage pathway thioredoxin pathway cysteine-type endopeptidase inhibitor activity ferrous iron binding adenosine nucleotides degradation I UDP-glucosyltransferase activity protein disulfide oxidoreductase activity | details |
| TissueCFM001349 | xylogalacturonan biosynthesis microtubule-based movement formation of glycosidic bonds, GlycosylTransferases: GTnc Protein_kinases_phosphatases, PPC:1.13.3: Leucine Rich Repeat Kinase III kinesin complex microtubule microtubule motor activity microtubule binding ATPase activity | details |
| TissueCFM001458 | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity cytoskeleton organization gluconeogenesis I glycolysis I (from glucose 6-phosphate) glycolysis IV (plant cytosol) Rubisco shunt microtubule binding | details |
| TissueCFM001571 | Hsp70 protein binding heat acclimation protein oligomerization receptor recycling retromer complex multivesicular body Transcription_related, Transcription factor: G2-like Transcription_related, Transcription factor: FAR1 retrograde transport, endosome to Golgi sulfate assimilation regulation of transcription, DNA-templated protein targeting to vacuole cellular response to oxidative stress oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor protein disulfide oxidoreductase activity protein transporter activity | details |
| TissueCFM001595 | fatty-acyl-CoA synthase activity protein farnesyltransferase activity CAAX-protein geranylgeranyltransferase activity inosine nucleosidase activity protein farnesyltransferase complex signal peptidase complex CAAX-protein geranylgeranyltransferase complex Transcription_related, Transcription factor: C2C2-Dof oxidoreductase activity Tropane, piperidine and pyridine alkaloid biosynthesis protein targeting to ER protein farnesylation inosine catabolic process protein geranylgeranylation regulation of meristem development jasmonic acid biosynthetic process signal peptide processing negative regulation of abscisic acid-activated signaling pathway adenine and adenosine salvage II guanosine nucleotides degradation I pyrimidine ribonucleosides salvage II pyrimidine salvage pathway regulation of cell shape UDP-glucosyltransferase activity adenosine nucleotides degradation I Protein export Terpenoid backbone biosynthesis jasmonic acid biosynthesis response to water deprivation peptidase activity Peroxisome membrane | details |
Expression profiles
 Show details about module gene expression profiling |