TissueCFM001338's detailed annotation
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Protein: Yellow color--query protein Green color--interaction proteins. Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
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Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontolog |
|---|---|---|
| Betalain biosynthesis | 0.001063908 | KEGG pathway |
| Tyrosine metabolism | 0.002923803 | KEGG pathway |
| inosine nucleosidase activity | 0.005890267 | GO:0047724 |
| oxidoreductase activity, acting on single donors with incorporation of molecular oxygen | 0.005890267 | GO:0016701 |
| cellular aromatic compound metabolic process | 0.006434743 | GO:0006725 |
| negative regulation of endopeptidase activity | 0.006434743 | GO:0010951 |
| inosine catabolic process | 0.006434743 | GO:0006148 |
| adenine and adenosine salvage II | 0.008332418 | plantCyc |
| guanosine nucleotides degradation I | 0.008332418 | plantCyc |
| pyrimidine ribonucleosides salvage II | 0.008332418 | plantCyc |
| pyrimidine salvage pathway | 0.008332418 | plantCyc |
| thioredoxin pathway | 0.008332418 | plantCyc |
| cysteine-type endopeptidase inhibitor activity | 0.009814935 | GO:0004869 |
| ferrous iron binding | 0.011775312 | GO:0008198 |
| adenosine nucleotides degradation I | 0.012140673 | plantCyc |
| UDP-glucosyltransferase activity | 0.03174874 | GO:0035251 |
| protein disulfide oxidoreductase activity | 0.047937092 | GO:0015035 |
Module member annotation
| Gene ID | Ortholog in Arabidopsis (Blast E-value) | Annotation in Arabidopsis |
|---|---|---|
| CRO_T007036 | AT3G12490 (2.00E-69) | ATCYS6|PHYTOCYSTATIN 6; ATCYSB|cystatin B |
| CRO_T013792 | AT4G15940 (4.00E-100) | Fumarylacetoacetate (FAA) hydrolase family |
| CRO_T022298 | AT4G15093 (2.00E-92) | AtLigB; LigB|catalytic LigB subunit of aromatic ring-opening dioxygenase family |
| CRO_T028488 | AT1G05620 (2.00E-128) | NSH2|nucleoside hydrolase 2; URH2|uridine-ribohydrolase 2 |
| CRO_T032689 | AT4G28730 (3.00E-15) | GrxC5|glutaredoxin C5 |
| CRO_T033787 | AT1G55340 (1.00E-44) | Protein of unknown function (DUF1639) |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TissueCFM000554 | molybdenum cofactor biosynthesis Transcriptional misregulation in cancers nucleic acid binding nucleotide binding carbohydrate metabolic process | details |
| TissueCFM000674 | cortical microtubule organization chaperone-mediated protein complex assembly prefoldin complex mRNA surveillance pathway translational initiation chaperone binding protein folding | details |
| TissueCFM000675 | nucleic acid binding histidine phosphotransfer kinase activity nucleotide binding protein histidine kinase binding Transcriptional misregulation in cancers cytokinin-activated signaling pathway phosphorelay signal transduction system mRNA surveillance pathway | details |
| TissueCFM001093 | superpathway of proto- and siroheme biosynthesis heme O biosynthetic process protoheme IX farnesyltransferase activity Tyrosine metabolism chaperone binding Ubiquitin_Proteasome_system, E3 adaptor: F-box | details |
| TissueCFM001411 | Betalain biosynthesis Tyrosine metabolism Ino80 complex oxidoreductase activity, acting on single donors with incorporation of molecular oxygen cellular aromatic compound metabolic process chromatin remodeling ferrous iron binding | details |
| TissueCFM001458 | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity cytoskeleton organization gluconeogenesis I glycolysis I (from glucose 6-phosphate) glycolysis IV (plant cytosol) Rubisco shunt microtubule binding | details |
| TissueCFM001500 | Transcription_related, Transcription regulator: RB TGF-beta signaling pathway calcium-dependent cysteine-type endopeptidase activity alternative oxidase activity cysteine-type endopeptidase inhibitor activity regulation of DNA endoreduplication proteolysis negative regulation of cell division negative regulation of endopeptidase activity Cell cycle aerobic respiration III (alternative oxidase pathway) regulation of transcription from RNA polymerase II promoter peptidase activity Spliceosome carbohydrate binding mitochondrial inner membrane integral component of membrane respiratory chain | details |
| TissueCFM001567 | site-specific DNA-methyltransferase (adenine-specific) activity phosphatidic acid transporter activity protein methyltransferase activity DNA methylation on adenine cellular response to stimulus tissue development plant organ development phospholipid transport response to virus negative regulation of defense response to virus anatomical structure morphogenesis regulation of response to stimulus mitochondrial intermembrane space protein methylation response to organic substance response to bacterium Tyrosine metabolism defense response to other organism response to osmotic stress single-organism cellular process translational initiation regulation of cellular process MAPK signaling pathway - plant RNA transport | details |
| TissueCFM001571 | Hsp70 protein binding heat acclimation protein oligomerization receptor recycling retromer complex multivesicular body Transcription_related, Transcription factor: G2-like Transcription_related, Transcription factor: FAR1 retrograde transport, endosome to Golgi sulfate assimilation regulation of transcription, DNA-templated protein targeting to vacuole cellular response to oxidative stress oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor protein disulfide oxidoreductase activity protein transporter activity | details |
| TissueCFM001595 | fatty-acyl-CoA synthase activity protein farnesyltransferase activity CAAX-protein geranylgeranyltransferase activity inosine nucleosidase activity protein farnesyltransferase complex signal peptidase complex CAAX-protein geranylgeranyltransferase complex Transcription_related, Transcription factor: C2C2-Dof oxidoreductase activity Tropane, piperidine and pyridine alkaloid biosynthesis protein targeting to ER protein farnesylation inosine catabolic process protein geranylgeranylation regulation of meristem development jasmonic acid biosynthetic process signal peptide processing negative regulation of abscisic acid-activated signaling pathway adenine and adenosine salvage II guanosine nucleotides degradation I pyrimidine ribonucleosides salvage II pyrimidine salvage pathway regulation of cell shape UDP-glucosyltransferase activity adenosine nucleotides degradation I Protein export Terpenoid backbone biosynthesis jasmonic acid biosynthesis response to water deprivation peptidase activity Peroxisome membrane | details |
| TissueCFM001708 | inosine nucleosidase activity protein targeting to ER inosine catabolic process signal peptidase complex adenine and adenosine salvage II guanosine nucleotides degradation I pyrimidine ribonucleosides salvage II pyrimidine salvage pathway signal peptide processing adenosine nucleotides degradation I DNA replication Protein export DNA recombination UDP-glucosyltransferase activity DNA repair peptidase activity | details |
Expression profiles
 Show details about module gene expression profiling |