TissueCFM000675's detailed annotation
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Protein: Yellow color--query protein Green color--interaction proteins. Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
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Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontolog |
|---|---|---|
| nucleic acid binding | 0.0128348 | GO:0003676 |
| histidine phosphotransfer kinase activity | 0.0128348 | GO:0009927 |
| nucleotide binding | 0.0128348 | GO:0000166 |
| protein histidine kinase binding | 0.0128348 | GO:0043424 |
| Transcriptional misregulation in cancers | 0.017046448 | KEGG pathway |
| cytokinin-activated signaling pathway | 0.021241872 | GO:0009736 |
| phosphorelay signal transduction system | 0.042382178 | GO:0000160 |
| mRNA surveillance pathway | 0.047439061 | KEGG pathway |
Module member annotation
| Gene ID | Ortholog in Arabidopsis (Blast E-value) | Annotation in Arabidopsis |
|---|---|---|
| CRO_T002838 | AT3G19780 (6.00E-30) | LOCATED IN: endomembrane system |
| CRO_T011899 | - | - |
| CRO_T013162 | AT4G17520 (2.00E-38) | Hyaluronan / mRNA binding family |
| CRO_T015319 | AT3G15010 (1.00E-15) | RNA-binding (RRM/RBD/RNP motifs) family protein |
| CRO_T018568 | AT3G22430 (3.00E-26) | |
| CRO_T024578 | AT3G21510 (1.00E-45) | AHP1|histidine-containing phosphotransmitter 1 |
| CRO_T033787 | AT1G55340 (1.00E-44) | Protein of unknown function (DUF1639) |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TissueCFM000554 | molybdenum cofactor biosynthesis Transcriptional misregulation in cancers nucleic acid binding nucleotide binding carbohydrate metabolic process | details |
| TissueCFM000674 | cortical microtubule organization chaperone-mediated protein complex assembly prefoldin complex mRNA surveillance pathway translational initiation chaperone binding protein folding | details |
| TissueCFM000784 | MAPK signaling pathway Ubiquitin_Proteasome_system, DUB: USP thiol-dependent ubiquitinyl hydrolase activity protein deubiquitination ubiquitin-dependent protein catabolic process small GTPase mediated signal transduction | details |
| TissueCFM001225 | nucleotide binding ureide catabolic process purine nucleobase catabolic process allantoin catabolic process Spliceosome allantoin degradation to glyoxylate II allantoin degradation to ureidoglycolate II (ammonia producing) ureidoglycine aminohydrolase activity molybdenum cofactor biosynthesis Transcriptional misregulation in cancers nucleic acid binding Transcription_related, Transcription factor: C3H | details |
| TissueCFM001338 | Betalain biosynthesis Tyrosine metabolism inosine nucleosidase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen cellular aromatic compound metabolic process negative regulation of endopeptidase activity inosine catabolic process adenine and adenosine salvage II guanosine nucleotides degradation I pyrimidine ribonucleosides salvage II pyrimidine salvage pathway thioredoxin pathway cysteine-type endopeptidase inhibitor activity ferrous iron binding adenosine nucleotides degradation I UDP-glucosyltransferase activity protein disulfide oxidoreductase activity | details |
| TissueCFM001368 | transferase activity, transferring hexosyl groups formation of glycosidic bonds, GlycosylTransferases: GTnc translational termination translation release factor activity, codon specific protein N-glycosylation (eukaryotic, high mannose) sesaminol glucoside biosynthesis triacylglycerol degradation | details |
| TissueCFM001384 | Golgi medial cisterna cis-Golgi network MAPK signaling pathway SNARE interactions in vesicular transport regulation of vesicle targeting, to, from or within Golgi intra-Golgi vesicle-mediated transport protein transport translational initiation ER to Golgi vesicle-mediated transport vesicle fusion SNARE binding SNAP receptor activity SNARE complex Ubiquitin_Proteasome_system, E3 adaptor: F-box translation initiation factor activity Golgi membrane | details |
| TissueCFM001385 | RNA transport actin filament polymerization Arp2/3 complex-mediated actin nucleation translational termination regulation of vesicle targeting, to, from or within Golgi intra-Golgi vesicle-mediated transport cis-Golgi network Arp2/3 protein complex Golgi medial cisterna vesicle fusion ER to Golgi vesicle-mediated transport protein transport SNARE interactions in vesicular transport SNARE binding actin binding translation release factor activity, codon specific SNAP receptor activity cell part Endocytosis mRNA surveillance pathway | details |
| TissueCFM001458 | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity cytoskeleton organization gluconeogenesis I glycolysis I (from glucose 6-phosphate) glycolysis IV (plant cytosol) Rubisco shunt microtubule binding | details |
| TissueCFM001571 | Hsp70 protein binding heat acclimation protein oligomerization receptor recycling retromer complex multivesicular body Transcription_related, Transcription factor: G2-like Transcription_related, Transcription factor: FAR1 retrograde transport, endosome to Golgi sulfate assimilation regulation of transcription, DNA-templated protein targeting to vacuole cellular response to oxidative stress oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor protein disulfide oxidoreductase activity protein transporter activity | details |
| TissueCFM001708 | inosine nucleosidase activity protein targeting to ER inosine catabolic process signal peptidase complex adenine and adenosine salvage II guanosine nucleotides degradation I pyrimidine ribonucleosides salvage II pyrimidine salvage pathway signal peptide processing adenosine nucleotides degradation I DNA replication Protein export DNA recombination UDP-glucosyltransferase activity DNA repair peptidase activity | details |
Expression profiles
 Show details about module gene expression profiling |