TreatCFM000270's detailed annotation
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Protein: Yellow color--query protein Green color--interaction proteins. Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
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Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontolog |
|---|---|---|
| CMP-3-deoxy-D-manno-octulosonate biosynthesis | 0.000827301 | plantCyc |
| 3-deoxy-8-phosphooctulonate synthase activity | 0.004723347 | GO:0008676 |
| voltage-gated potassium channel activity | 0.01886995 | GO:0005249 |
| Lipopolysaccharide biosynthesis | 0.021241872 | KEGG pathway |
| clathrin adaptor complex | 0.022388193 | GO:0030131 |
| GTPase activator activity | 0.023558181 | GO:0005096 |
| cellular response to DNA damage stimulus | 0.024552505 | GO:0006974 |
| potassium ion transport | 0.024552505 | GO:0006813 |
| regulation of membrane potential | 0.024552505 | GO:0042391 |
| Fanconi anemia pathway | 0.028254785 | KEGG pathway |
| Lysosome | 0.028254785 | KEGG pathway |
| protein transporter activity | 0.029980824 | GO:0008565 |
| biosynthetic process | 0.033729512 | GO:0009058 |
| ion transmembrane transport | 0.033729512 | GO:0034220 |
| positive regulation of GTPase activity | 0.033729512 | GO:0043547 |
| DNA metabolic process | 0.033729512 | GO:0006259 |
| cytoplasm | 0.034041583 | GO:0005737 |
| Plant-pathogen interaction | 0.044578439 | KEGG pathway |
| Endocytosis | 0.046825005 | KEGG pathway |
| vesicle-mediated transport | 0.047108464 | GO:0016192 |
| formation of glycosidic bonds, GlycosylTransferases: GTnc | 0.049602139 | cazy family |
Module member annotation
| Gene ID | Ortholog in Arabidopsis (Blast E-value) | Annotation in Arabidopsis |
|---|---|---|
| CRO_T004205 | AT1G16340 (5.00E-131) | ATKDSA2; ATKSDA|Aldolase superfamily protein |
| CRO_T008127 | AT2G24610 (0) | ATCNGC14|cyclic nucleotide-gated channel 14 |
| CRO_T011644 | AT4G23460 (9.00E-108) | Adaptin family protein |
| CRO_T014242 | AT5G44750 (8.00E-37) | ATREV1|HOMOLOG OF REVERSIONLESS 1 |
| CRO_T017750 | AT4G05330 (4.00E-20) | AGD13|ARF-GAP domain 13 |
| CRO_T019884 | AT4G28010 (6.00E-28) | RPF5|RNA processing factor 5 |
| CRO_T022370 | AT1G44120 (0) | CSI2|CELLULOSE SYNTHASE INTERACTIVE 2 |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TreatCFM000017 | Oxidative phosphorylation mitochondrion NADH dehydrogenase (ubiquinone) activity mitochondrial inner membrane heme transporter activity heme transport cytochrome-c oxidase activity respiratory chain cytochrome complex assembly hydrogen ion transmembrane transport ATP synthesis coupled electron transport heme binding aerobic respiration hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances aerobic electron transport chain electron transport chain generation of precursor metabolites and energy ATP synthesis coupled proton transport mitochondrial electron transport, NADH to ubiquinone hydrogen ion transmembrane transporter activity quinone binding photosynthetic electron transport in photosystem II succinate dehydrogenase activity electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity succinate dehydrogenase complex | details |
| TreatCFM000044 | details | |
| TreatCFM000050 | details | |
| TreatCFM000751 | RNA transport nuclear matrix nucleobase-containing compound transmembrane transporter activity Protein_kinases_phosphatases, PPC:4.5.1: MAPK Family Ubiquitin_Proteasome_system, DUB: USP tRNA re-export from nucleus meristem initiation tRNA binding thiol-dependent ubiquitin-specific protease activity nuclear pore Ran GTPase binding GTPase activator activity Endocytosis flower development protein deubiquitination | details |
| TreatCFM000753 | details | |
| TreatCFM000785 | mitotic spindle assembly checkpoint Oxidative phosphorylation | details |
| TreatCFM001101 | mitochondrial RNA metabolic process Transcription_related, Transcription regulator: SNF2 RNA modification large ribosomal subunit rRNA binding protein domain specific binding MAPK signaling pathway - yeast Homologous recombination mitochondrial large ribosomal subunit | details |
| TreatCFM001331 | 3-deoxy-8-phosphooctulonate synthase activity thymidylate kinase activity response to extracellular stimulus dUDP biosynthetic process dTTP biosynthetic process dTDP biosynthetic process organ morphogenesis regulation of root development reactive oxygen species metabolic process lateral root development CMP-3-deoxy-D-manno-octulosonate biosynthesis pyrimidine deoxyribonucleotide phosphorylation pyrimidine deoxyribonucleotides de novo biosynthesis II superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli) fruit development endoplasmic reticulum unfolded protein response uridylate kinase activity defense response to fungus, incompatible interaction pyrimidine deoxyribonucleotides de novo biosynthesis I endoplasmic reticulum heterotrimeric G-protein complex negative regulation of abscisic acid-activated signaling pathway histone acetyltransferase activity Cul4-RING E3 ubiquitin ligase complex histone acetylation Transcription_related, Transcription regulator: mTERF Lipopolysaccharide biosynthesis jasmonic acid mediated signaling pathway response to ethylene Ras signaling pathway Pyrimidine metabolism biosynthetic process helicase activity RNA degradation | details |
| TreatCFM001588 | L-leucine biosynthesis formation of glycosidic bonds, GlycosylTransferases: GTnc Protein_kinases_phosphatases, PPC:1.1.1: Leucine-rich transmembrane protein kinase/Strubbelig Receptor Family 1 organonitrogen compound biosynthetic process organic acid biosynthetic process water transport cellular water homeostasis glycerol transport ion transmembrane transport 2-Oxocarboxylic acid metabolism oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor large ribosomal subunit rRNA binding glycerol channel activity water channel activity | details |
| TreatCFM001675 | histone H4 acetylation histone H2A acetylation Protein_kinases_phosphatases, PPC:1.8.1: Leucine Rich Repeat Kinase I NuA4 histone acetyltransferase complex negative regulation of transcription, DNA-templated chromatin remodeling activation of MAPKK activity MAPK cascade MAP kinase kinase kinase activity large ribosomal subunit rRNA binding DNA repair | details |
| TreatCFM001694 | Protein_kinases_phosphatases, PPC:1.2.1: Receptor Like Cytoplasmic Kinase VIII outer membrane-bounded periplasmic space clathrin adaptor complex Fanconi anemia pathway Lysosome cellular response to DNA damage stimulus cytochrome complex assembly DNA metabolic process | details |
| TreatCFM001710 | Endocytosis positive regulation of GTPase activity GTP:GDP antiporter activity regulation of vesicle targeting, to, from or within Golgi endosome transport via multivesicular body sorting pathway root hair cell differentiation cell adhesion longitudinal axis specification establishment of planar polarity basipetal auxin transport regulation of ARF protein signal transduction cellular response to DNA damage stimulus ARF guanyl-nucleotide exchange factor activity Fanconi anemia pathway Lysosome endosome membrane lateral root formation cytokinesis by cell plate formation clathrin adaptor complex phloem or xylem histogenesis unidimensional cell growth GTPase activator activity DNA metabolic process protein transporter activity protein homodimerization activity protein transport formation of glycosidic bonds, GlycosylTransferases: GTnc | details |
| TreatCFM001827 | Fanconi anemia pathway RNA lariat debranching enzyme activity Endocytosis DNA metabolic process RNA phosphodiester bond hydrolysis, endonucleolytic mRNA splicing, via spliceosome DNA biosynthetic process translational initiation cellular response to DNA damage stimulus positive regulation of GTPase activity DNA repair embryo development ending in seed dormancy nucleotidyltransferase activity GTPase activator activity | details |
| TreatCFM001930 | response to extracellular stimulus lateral root development reactive oxygen species metabolic process organ morphogenesis endoplasmic reticulum unfolded protein response regulation of root development fruit development defense response to fungus, incompatible interaction leucopelargonidin and leucocyanidin biosynthesis negative regulation of abscisic acid-activated signaling pathway Ras signaling pathway histone acetylation Transcription_related, Transcription regulator: mTERF heterotrimeric G-protein complex jasmonic acid mediated signaling pathway Cul4-RING E3 ubiquitin ligase complex Phenylpropanoid biosynthesis response to ethylene RNA degradation exocytosis exocyst | details |
| TreatCFM002037 | CMP-3-deoxy-D-manno-octulosonate biosynthesis Spliceosome U6 snRNA binding U5 snRNA binding U2 snRNA binding pre-mRNA intronic binding 3-deoxy-8-phosphooctulonate synthase activity second spliceosomal transesterification activity U1 snRNA binding Lipopolysaccharide biosynthesis production of ta-siRNAs involved in RNA interference spliceosomal tri-snRNP complex assembly mRNA export from nucleus cytokinesis by cell plate formation THO complex part of transcription export complex cell plate U5 snRNP biosynthetic process small GTPase mediated signal transduction catalytic step 2 spliceosome Endocytosis | details |
| TreatCFM002101 | CMP-3-deoxy-D-manno-octulosonate biosynthesis RNA degradation Lipopolysaccharide biosynthesis fruit development organ morphogenesis reactive oxygen species metabolic process endoplasmic reticulum unfolded protein response lateral root development regulation of root development response to extracellular stimulus defense response to fungus, incompatible interaction 3-deoxy-8-phosphooctulonate synthase activity Autophagy - animal Ras signaling pathway Protein_kinases_phosphatases, PPC:1.1.1: Leucine-rich transmembrane protein kinase/Strubbelig Receptor Family 1 ATG1/ULK1 kinase complex heterotrimeric G-protein complex negative regulation of abscisic acid-activated signaling pathway autophagy histone acetylation ATP binding large ribosomal subunit rRNA binding Cul4-RING E3 ubiquitin ligase complex histone acetyltransferase activity Transcription_related, Transcription regulator: mTERF jasmonic acid mediated signaling pathway response to ethylene poly(A) RNA binding biosynthetic process RNA processing | details |
Expression profiles
 Show details about module gene expression profiling |