TreatCFM001936's detailed annotation
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Protein: Yellow color--query protein Green color--interaction proteins. Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
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Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontolog |
|---|---|---|
| geranylgeraniol kinase activity | 0.006515544 | GO:0052671 |
| CTP:2-trans,-6-trans-farnesol kinase activity | 0.006515544 | GO:0052669 |
| geraniol kinase activity | 0.006515544 | GO:0052670 |
| postreplication repair | 0.00719239 | GO:0006301 |
| carpel development | 0.00719239 | GO:0048440 |
| protein K63-linked ubiquitination | 0.00719239 | GO:0070534 |
| farnesol metabolic process | 0.00719239 | GO:0016487 |
| tRNA pseudouridine synthesis | 0.00719239 | GO:0031119 |
| farnesylcysteine salvage pathway | 0.007794044 | plantCyc |
| Ubiquitin_Proteasome_system, E2: UBC | 0.009653515 | ubs family |
| Nucleotide excision repair | 0.010789044 | KEGG pathway |
| Toll and Imd signaling pathway | 0.010789044 | KEGG pathway |
| adenosine ribonucleotides de novo biosynthesis | 0.011664498 | plantCyc |
| MAPK signaling pathway | 0.017959437 | KEGG pathway |
| deaminase activity | 0.021974045 | GO:0019239 |
| ABC transporters | 0.022865157 | KEGG pathway |
| Terpenoid backbone biosynthesis | 0.02792418 | KEGG pathway |
| pseudouridine synthase activity | 0.02928055 | GO:0009982 |
Module member annotation
| Gene ID | Ortholog in Arabidopsis (Blast E-value) | Annotation in Arabidopsis |
|---|---|---|
| CRO_T010291 | AT5G58560 (1.00E-82) | FOLK|farnesol kinase |
| CRO_T010926 | AT5G16630 (0) | ATRAD4; RAD4|DNA repair protein Rad4 family |
| CRO_T011703 | AT3G19440 (4.00E-121) | Pseudouridine synthase family protein |
| CRO_T017850 | AT5G55990 (4.00E-113) | CBL2|calcineurin B-like protein 2 |
| CRO_T022760 | AT1G70650 (2.00E-51) | Ran BP2/NZF zinc finger-like superfamily protein |
| CRO_T027007 | - | - |
| CRO_T027841 | AT3G13100 (0) | ABCC7|ATP-binding cassette C7; ATMRP7|multidrug resistance-associated protein 7 |
| CRO_T029737 | AT4G30260 (1.00E-04) | YIP4b|YPT/RAB GTPase Interacting Protein 4b |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TreatCFM000160 | Toll and Imd signaling pathway activation of MAPK activity defense response, incompatible interaction mitochondrial mRNA modification protein K63-linked ubiquitination postreplication repair sugar mediated signaling pathway Protein_kinases_phosphatases, PPC:4.1.4: MAP2K MAP kinase kinase activity MAPK cascade Transcription_related, Transcription regulator: PHD Ubiquitin_Proteasome_system, E2: UBC MAP kinase activity MAPK signaling pathway - plant | details |
| TreatCFM000356 | adenosine ribonucleotides de novo biosynthesis Protein_kinases_phosphatases, PPC:4.1.4: MAP2K Transcription_related, Transcription regulator: LUG xyloglucan biosynthetic process endomembrane system organization fucose biosynthetic process defense response, incompatible interaction activation of MAPK activity 9,9'-di-cis-zeta-carotene desaturation to 7,9,7',9'-tetra-cis-lycopene vacuolar proton-transporting V-type ATPase, V1 domain glycerol-3-phosphate O-acyltransferase activity 9,9'-dicis-carotene:quinone oxidoreductase activity MAP kinase kinase activity 7,9,9'-tricis-neurosporene:quinone oxidoreductase activity cutin biosynthetic process integral component of Golgi membrane formation of glycosidic bonds, GlycosylTransferases: GTnc MAP kinase activity glycerol-3-phosphate 2-O-acyltransferase activity galactosyltransferase activity phosphatase activity | details |
| TreatCFM000379 | Toll and Imd signaling pathway postreplication repair fatty acid beta-oxidation protein K63-linked ubiquitination protein monoubiquitination protein import into peroxisome matrix attachment of peroxisome to chloroplast photorespiration Peroxisome Protein_kinases_phosphatases, PPC:2.1.2: Ankyrin Repeat Domain Kinase integral component of peroxisomal membrane Ubiquitin_Proteasome_system, E2: UBC embryo development ending in seed dormancy | details |
| TreatCFM000394 | protein N-glycosylation (eukaryotic, high mannose) adhesion to carbohydrates, Carbohydrate-Binding Modules: CBM57 formation of glycosidic bonds, GlycosylTransferases: GTnc hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc Toll and Imd signaling pathway root epidermal cell differentiation regulation of salicylic acid metabolic process cell wall macromolecule catabolic process glutaminyl-tRNAGln biosynthesis via transamidation postreplication repair protein K63-linked ubiquitination glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity DNA topoisomerase activity mitochondrial translation response to nitrate Ubiquitin_Proteasome_system, E2: UBC chitin catabolic process multidimensional cell growth glutamyl-tRNA(Gln) amidotransferase complex Aminoacyl-tRNA biosynthesis Homologous recombination N-Glycan biosynthesis response to heat chitinase activity response to water deprivation response to cytokinin cellulose biosynthetic process response to salt stress ubiquitin protein ligase binding transferase activity, transferring hexosyl groups | details |
| TreatCFM000473 | Toll and Imd signaling pathway tryptophan metabolic process postreplication repair protein K63-linked ubiquitination Ubiquitin_Proteasome_system, E2: UBC cell wall organization or biogenesis O-acetyltransferase activity ubiquitin protein ligase binding lyase activity ligase activity ubiquitin protein ligase activity Purine metabolism | details |
| TreatCFM000515 | chloroplast accumulation movement microtubule-based movement microtubule motor activity microtubule binding geranylgeraniol kinase activity geraniol kinase activity CTP:2-trans,-6-trans-farnesol kinase activity farnesol metabolic process peptidyl-proline hydroxylation phosphatidylglycerol biosynthetic process carpel development protein K63-linked ubiquitination postreplication repair long-chain fatty acid metabolic process Ubiquitin_Proteasome_system, E2: UBC Toll and Imd signaling pathway glycerol-3-phosphate O-acyltransferase activity procollagen-proline 4-dioxygenase activity long-chain fatty acid-CoA ligase activity Arginine and proline metabolism Fatty acid metabolism Glycerolipid metabolism Terpenoid backbone biosynthesis L-ascorbic acid binding | details |
| TreatCFM000610 | Toll and Imd signaling pathway postreplication repair protein K63-linked ubiquitination Ubiquitin_Proteasome_system, E2: UBC mediator complex ubiquitin protein ligase binding ligase activity ubiquitin protein ligase activity | details |
| TreatCFM000713 | Toll and Imd signaling pathway Protein_kinases_phosphatases, PPC:4.1.4: MAP2K activation of MAPK activity defense response, incompatible interaction protein K63-linked ubiquitination postreplication repair MAP kinase kinase activity Ubiquitin_Proteasome_system, E2: UBC MAPK cascade MAP kinase activity cytoplasm MAPK signaling pathway - plant ubiquitin protein ligase binding | details |
| TreatCFM000819 | Toll and Imd signaling pathway postreplication repair protein K63-linked ubiquitination Ubiquitin_Proteasome_system, E2: UBC vindoline and vinblastine biosynthesis spliceosomal complex mRNA splicing, via spliceosome Spliceosome | details |
| TreatCFM000956 | Toll and Imd signaling pathway polycistronic mRNA processing peptidyl-lysine methylation peptidyl-proline hydroxylation cellular manganese ion homeostasis chloroplast mRNA processing response to copper ion response to manganese ion manganese ion transmembrane transport protein K63-linked ubiquitination postreplication repair response to zinc ion regulation of sequestering of zinc ion Ubiquitin_Proteasome_system, E2: UBC Arginine and proline metabolism manganese:proton antiporter activity chloroplast nucleoid late endosome procollagen-proline 4-dioxygenase activity zinc II ion transmembrane transport protein-lysine N-methyltransferase activity zinc ion transmembrane transporter activity L-ascorbic acid binding ubiquitin protein ligase binding | details |
| TreatCFM001095 | Endocytosis L-leucine biosynthesis Legionellosis Toll and Imd signaling pathway Ubiquitin_Proteasome_system, E2: UBC vacuolar transport postreplication repair cytokinesis by cell plate formation protein K63-linked ubiquitination cellular amino acid biosynthetic process 2-Oxocarboxylic acid metabolism hydro-lyase activity small GTPase mediated signal transduction cell plate 4 iron, 4 sulfur cluster binding isomerase activity ubiquitin protein ligase binding | details |
| TreatCFM001096 | L-leucine biosynthesis Legionellosis Toll and Imd signaling pathway Ubiquitin_Proteasome_system, E2: UBC protein K63-linked ubiquitination postreplication repair 2-Oxocarboxylic acid metabolism hydro-lyase activity response to stimulus cellular amino acid biosynthetic process protein catabolic process 4 iron, 4 sulfur cluster binding aspartic-type endopeptidase activity ubiquitin protein ligase binding isomerase activity | details |
| TreatCFM001244 | organic cyclic compound metabolic process long-chain fatty acid biosynthetic process small molecule metabolic process response to molecule of fungal origin phosphatidylserine biosynthetic process phosphatidylethanolamine biosynthesis I superpathway of phospholipid biosynthesis II (plants) heterocycle metabolic process sphingosine N-acyltransferase activity tocopherol cyclase activity vitamin E biosynthesis (tocopherols) cellular lipid metabolic process Ubiquitin_Proteasome_system, E3: U-box MAPK signaling pathway Ubiquinone and other terpenoid-quinone biosynthesis Glycerophospholipid metabolism chloroplast part | details |
| TreatCFM001321 | Toll and Imd signaling pathway postreplication repair protein K63-linked ubiquitination Ubiquitin_Proteasome_system, E2: UBC ubiquitin protein ligase activity transferase activity, transferring acyl groups ligase activity ubiquitin protein ligase binding | details |
| TreatCFM001403 | Toll and Imd signaling pathway phenylpropanoid metabolic process postreplication repair protein K63-linked ubiquitination protein homooligomerization Ubiquitin_Proteasome_system, E2: UBC NADPH-hemoprotein reductase activity ubiquitin protein ligase binding FMN binding response to abscisic acid ubiquitin protein ligase activity ligase activity | details |
| TreatCFM001541 | ligase activity Glucagon signaling pathway Toll and Imd signaling pathway transcriptional repressor complex glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity postreplication repair heparan sulfate proteoglycan biosynthetic process glycosaminoglycan biosynthetic process protein K63-linked ubiquitination Cell cycle glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity formation of glycosidic bonds, GlycosylTransferases: GTnc Ubiquitin_Proteasome_system, E3: HECT Transcription_related, Transcription factor: MYB-related Ubiquitin_Proteasome_system, E2: UBC ubiquitin protein ligase binding Ubiquitin mediated proteolysis | details |
| TreatCFM001542 | ligase activity transcriptional repressor complex Glucagon signaling pathway Toll and Imd signaling pathway postreplication repair vegetative phase change protein K63-linked ubiquitination organ senescence detection of nutrient developmental process involved in reproduction sugar mediated signaling pathway Cell cycle primary root development Apelin signaling pathway cytoplasm Protein_kinases_phosphatases, PPC:4.2.4: SNF1 Related Protein Kinase (SnRK) Transcription_related, Transcription factor: MYB-related Ubiquitin_Proteasome_system, E2: UBC Ubiquitin_Proteasome_system, E3: HECT nucleus abscisic acid-activated signaling pathway Ubiquitin mediated proteolysis | details |
| TreatCFM001640 | trans-Golgi network outer membrane-bounded periplasmic space Calcium signaling pathway MAPK signaling pathway early endosome manganese ion homeostasis manganese-transporting ATPase activity manganese ion transmembrane transport cell plate assembly cytochrome complex assembly calcium ion transmembrane transport ATP binding calcium-transporting ATPase activity RNA secondary structure unwinding root development translational initiation | details |
| TreatCFM001733 | CTP:2-trans,-6-trans-farnesol kinase activity geranylgeraniol kinase activity geraniol kinase activity tocopherol cyclase activity farnesylcysteine salvage pathway vitamin E biosynthesis (tocopherols) small molecule metabolic process organic cyclic compound metabolic process farnesol metabolic process heterocycle metabolic process carpel development cellular lipid metabolic process magnesium ion transmembrane transport magnesium ion transport magnesium ion transmembrane transporter activity iron-sulfur cluster assembly MAPK signaling pathway Terpenoid backbone biosynthesis Ubiquinone and other terpenoid-quinone biosynthesis nucleotidyltransferase activity response to abscisic acid chloroplast part | details |
| TreatCFM001746 | Protein_kinases_phosphatases, PPC:4.1.4: MAP2K Toll and Imd signaling pathway regulation of chromatin silencing protein K63-linked ubiquitination isoleucyl-tRNA aminoacylation regulation of histone H3-K9 methylation defense response, incompatible interaction ribosomal large subunit export from nucleus resolution of meiotic recombination intermediates activation of MAPK activity postreplication repair actin cytoskeleton organization regulation of translational fidelity ATP binding MAP kinase kinase activity isoleucine-tRNA ligase activity aminoacyl-tRNA editing activity DNA clamp loader activity Protein_kinases_phosphatases, PPC:4.5.2: CDC2 Like Kinase Family MAP kinase activity Ubiquitin_Proteasome_system, E2: UBC ribosomal large subunit biogenesis DNA replication factor C complex ubiquitin protein ligase binding MAPK cascade DNA replication Aminoacyl-tRNA biosynthesis cell cytoplasm MAPK signaling pathway - plant response to abscisic acid DNA repair | details |
| TreatCFM001823 | Toll and Imd signaling pathway protein monoubiquitination protein import into peroxisome matrix protein homooligomerization postreplication repair phenylpropanoid metabolic process attachment of peroxisome to chloroplast fatty acid beta-oxidation protein K63-linked ubiquitination photorespiration Peroxisome NADPH-hemoprotein reductase activity integral component of peroxisomal membrane cytosol Ubiquitin_Proteasome_system, E2: UBC response to abscisic acid FMN binding ubiquitin protein ligase binding | details |
| TreatCFM001895 | vitamin E biosynthesis (tocopherols) tocopherol cyclase activity small molecule metabolic process organic cyclic compound metabolic process heterocycle metabolic process resolution of recombination intermediates Smc5-Smc6 complex vacuolar proton-transporting V-type ATPase, V1 domain plant-type vacuole cellular lipid metabolic process chromosome organization double-strand break repair via homologous recombination MAPK signaling pathway Ubiquinone and other terpenoid-quinone biosynthesis chloroplast part iron-sulfur cluster assembly unidimensional cell growth response to heat ATP hydrolysis coupled proton transport hydrogen ion transmembrane transporter activity heat shock protein binding mitochondrial matrix | details |
| TreatCFM001953 | Toll and Imd signaling pathway protein import into peroxisome matrix protein K63-linked ubiquitination attachment of peroxisome to chloroplast defense response, incompatible interaction activation of MAPK activity fatty acid beta-oxidation protein monoubiquitination postreplication repair photorespiration Protein_kinases_phosphatases, PPC:4.1.4: MAP2K integral component of peroxisomal membrane Peroxisome MAPK cascade MAP kinase kinase activity cytoplasm Transcription_related, Transcription factor: C3H Ubiquitin_Proteasome_system, E2: UBC MAPK signaling pathway - plant embryo development ending in seed dormancy MAP kinase activity | details |
| TreatCFM001975 | hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc Glycosaminoglycan degradation geraniol kinase activity organic cyclic compound metabolic process long-chain fatty acid biosynthetic process CTP:2-trans,-6-trans-farnesol kinase activity response to molecule of fungal origin geranylgeraniol kinase activity small molecule metabolic process tocopherol cyclase activity farnesol metabolic process adenyl-nucleotide exchange factor activity sphingosine N-acyltransferase activity heterocycle metabolic process carpel development cellular lipid metabolic process Sphingolipid metabolism ceramide degradation farnesylcysteine salvage pathway vitamin E biosynthesis (tocopherols) chaperone binding Ubiquinone and other terpenoid-quinone biosynthesis Terpenoid backbone biosynthesis gluconeogenesis I glycolysis I (from glucose 6-phosphate) glycolysis IV (plant cytosol) Rubisco shunt isomerase activity nucleotidyltransferase activity regulation of catalytic activity | details |
| TreatCFM002139 | geranylgeraniol kinase activity geraniol kinase activity CTP:2-trans,-6-trans-farnesol kinase activity soluble NSF attachment protein activity farnesylcysteine salvage pathway SNARE complex disassembly farnesol metabolic process protein import syntaxin binding protein targeting membrane fusion carpel development adenosine ribonucleotides de novo biosynthesis Transcription_related, Transcription factor: FAR1 ABC transporters Autophagy - yeast Protein export Terpenoid backbone biosynthesis ATP binding nucleotidyltransferase activity amino acid binding | details |
| TreatCFM002140 | postreplication repair protein K63-linked ubiquitination production of ta-siRNAs involved in RNA interference mRNA export from nucleus Toll and Imd signaling pathway THO complex part of transcription export complex NAD/NADH phosphorylation and dephosphorylation Nicotinate and nicotinamide metabolism Ubiquitin_Proteasome_system, E2: UBC ubiquitin protein ligase binding ligase activity ubiquitin protein ligase activity | details |
Expression profiles
 Show details about module gene expression profiling |