TreatCFM002136's detailed annotation
|
Protein: Yellow color--query protein Green color--interaction proteins. Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
| This network produced by cytoscapeweb |
Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontolog |
|---|---|---|
| Ubiquitin_Proteasome_system, DUB: USP | 0.004778752 | ubs family |
| thiol oxidase activity | 0.009029289 | GO:0016972 |
| Ras signaling pathway | 0.012215977 | KEGG pathway |
| maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 0.023447049 | GO:0000463 |
| cellular protein metabolic process | 0.024281347 | GO:0044267 |
| cytoplasmic translation | 0.024281347 | GO:0002181 |
| cysteine-type peptidase activity | 0.033827325 | GO:0008234 |
| poly(A) RNA binding | 0.036058494 | GO:0044822 |
| metal ion binding | 0.038708506 | GO:0046872 |
| identical protein binding | 0.038708506 | GO:0042802 |
| small GTPase mediated signal transduction | 0.043450976 | GO:0007264 |
Module member annotation
| Gene ID | Ortholog in Arabidopsis (Blast E-value) | Annotation in Arabidopsis |
|---|---|---|
| CRO_T002214 | AT1G65920 (0) | Regulator of chromosome condensation (RCC1) family with FYVE zinc finger domain |
| CRO_T007308 | AT1G49880 (7.00E-23) | EMB3106|EMBRYO DEFECTIVE 3106; Erv1|Erv1 |
| CRO_T016279 | AT3G54840 (3.00E-20) | ARA6; ARA-6; AtARA6; ATRAB5C; ATRABF1; RABF1|Ras-related small GTP-binding family protein |
| CRO_T018539 | AT1G04860 (1.00E-21) | UBP2|ubiquitin-specific protease 2 |
| CRO_T026647 | AT1G28410 (1.00E-39) | unknown protein |
| CRO_T033054 | AT1G80750 (6.00E-72) | Ribosomal protein L30/L7 family protein |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TreatCFM001396 | MicroRNAs in cancer L-amino acid transport L-alpha-amino acid transmembrane transport L-amino acid transmembrane transporter activity response to stress antiporter activity | details |
| TreatCFM001492 | formation of glycosidic bonds, GlycosylTransferases: GTnc hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc alpha-1,3-mannosyltransferase activity galactoside 2-alpha-L-fucosyltransferase activity mannosylglycoprotein endo-beta-mannosidase activity ceramide metabolic process L-amino acid transport fucosylation nucleocytoplasmic transport xyloglucan biosynthetic process mannosylation L-alpha-amino acid transmembrane transport hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides plant-type cell wall biogenesis fatty acid β-oxidation II (peroxisome) protein N-glycosylation (eukaryotic, high mannose) unsaturated, even numbered fatty acid β-oxidation L-amino acid transmembrane transporter activity MicroRNAs in cancer translation | details |
| TreatCFM001723 | cytosolic large ribosomal subunit Ribosome transcription coactivator activity poly(A) RNA binding structural constituent of ribosome maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) cytoplasmic translation intracellular part formation of glycosidic bonds, GlycosylTransferases: GTnc | details |
| TreatCFM001726 | L-phenylalanine biosynthesis II L-tyrosine biosynthesis II Transcription_related, Transcription factor: Whirly hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc MicroRNAs in cancer L-amino acid transport chorismate metabolic process L-alpha-amino acid transmembrane transport Ubiquitin_Proteasome_system, DUB: USP aromatic amino acid family biosynthetic process chorismate mutase activity defense response to fungus cellular protein metabolic process L-amino acid transmembrane transporter activity cysteine-type peptidase activity positive regulation of transcription, DNA-templated Biosynthesis of amino acids antiporter activity hydrolase activity, acting on ester bonds | details |
| TreatCFM001781 | Ras signaling pathway cytoskeletal part microtubule cytoskeleton cytokinesis by cell plate formation | details |
| TreatCFM001821 | mRNA splicing, via spliceosome Spliceosome Transcription_related, Transcription factor: Whirly MicroRNAs in cancer hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc DNA replication factor A complex L-amino acid transport L-alpha-amino acid transmembrane transport Ubiquitin_Proteasome_system, DUB: USP Prp19 complex Cul4-RING E3 ubiquitin ligase complex COPII vesicle coat Proteasome precatalytic spliceosome catalytic step 2 spliceosome defense response to fungus regulation of gene expression RNA secondary structure unwinding ER to Golgi vesicle-mediated transport cellular protein metabolic process positive regulation of transcription, DNA-templated | details |
| TreatCFM001854 | glucan 1,3-alpha-glucosidase activity thiol oxidase activity adenosine ribonucleotides de novo biosynthesis posttranscriptional regulation of gene expression heat acclimation mitochondrion proton-transporting ATP synthase complex, catalytic core F(1) N-Glycan biosynthesis response to cold hyperosmotic salinity response response to water deprivation ATP synthesis coupled proton transport ATP hydrolysis coupled proton transport proton-transporting ATPase activity, rotational mechanism proton-transporting ATP synthase activity, rotational mechanism identical protein binding response to abscisic acid | details |
| TreatCFM001924 | Ras signaling pathway Protein_kinases_phosphatases, PPC:2.1.5: ATN1 Like Family 3-phosphoinositide biosynthesis D-myo-inositol (1,4,5)-trisphosphate biosynthesis peptidyl-arginine methylation cellular response to extracellular stimulus 1-phosphatidylinositol 4-kinase activity protein-arginine omega-N asymmetric methyltransferase activity SUMO transferase activity histone-arginine N-methyltransferase activity Transcription_related, Transcription regulator: PHD protein sumoylation cell growth phosphatidylinositol phosphorylation response to salt stress protein autophosphorylation zinc ion binding | details |
| TreatCFM002023 | N-Glycan biosynthesis carbohydrate binding thiol oxidase activity glucan 1,3-alpha-glucosidase activity alpha-1,4-glucosidase activity maltose alpha-glucosidase activity potassium ion binding pyruvate kinase activity glycolysis I (from glucose 6-phosphate) glycolysis IV (plant cytosol) Rubisco shunt maltose metabolic process glycolytic process response to water deprivation hyperosmotic salinity response response to cold identical protein binding response to abscisic acid | details |
| TreatCFM002074 | proteolysis L-alpha-amino acid transmembrane transport L-amino acid transport Ubiquitin_Proteasome_system, DUB: USP MicroRNAs in cancer cellular protein metabolic process cysteine-type peptidase activity L-amino acid transmembrane transporter activity metal ion binding aspartic-type endopeptidase activity antiporter activity | details |
| TreatCFM002137 | Ubiquitin_Proteasome_system, DUB: USP oxidoreductase activity, acting on peroxide as acceptor antioxidant activity Ras signaling pathway maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) cellular protein metabolic process cytoplasmic translation cysteine-type peptidase activity poly(A) RNA binding metal ion binding small GTPase mediated signal transduction | details |
Expression profiles
 Show details about module gene expression profiling |