TreatCFM001492's detailed annotation
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Protein: Yellow color--query protein Green color--interaction proteins. Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
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Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontolog |
|---|---|---|
| formation of glycosidic bonds, GlycosylTransferases: GTnc | 0.004720975 | cazy family |
| hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc | 0.004720975 | cazy family |
| alpha-1,3-mannosyltransferase activity | 0.014914711 | GO:0000033 |
| galactoside 2-alpha-L-fucosyltransferase activity | 0.014914711 | GO:0008107 |
| mannosylglycoprotein endo-beta-mannosidase activity | 0.014914711 | GO:0033947 |
| ceramide metabolic process | 0.02228581 | GO:0006672 |
| L-amino acid transport | 0.02228581 | GO:0015807 |
| fucosylation | 0.02228581 | GO:0036065 |
| nucleocytoplasmic transport | 0.02228581 | GO:0006913 |
| xyloglucan biosynthetic process | 0.02228581 | GO:0009969 |
| mannosylation | 0.02228581 | GO:0097502 |
| L-alpha-amino acid transmembrane transport | 0.02228581 | GO:1902475 |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides | 0.022363474 | GO:0016811 |
| plant-type cell wall biogenesis | 0.025990128 | GO:0009832 |
| fatty acid β-oxidation II (peroxisome) | 0.032008373 | plantCyc |
| protein N-glycosylation (eukaryotic, high mannose) | 0.032008373 | plantCyc |
| unsaturated, even numbered fatty acid β-oxidation | 0.032008373 | plantCyc |
| L-amino acid transmembrane transporter activity | 0.044675441 | GO:0015179 |
| MicroRNAs in cancer | 0.044711626 | KEGG pathway |
| translation | 0.049778206 | GO:0006412 |
Module member annotation
| Gene ID | Ortholog in Arabidopsis (Blast E-value) | Annotation in Arabidopsis |
|---|---|---|
| CRO_T004739 | AT4G09980 (4.00E-115) | EMB1691|EMBRYO DEFECTIVE 1691 |
| CRO_T012488 | - | - |
| CRO_T013458 | AT1G58030 (9.00E-94) | CAT2|cationic amino acid transporter 2 |
| CRO_T015394 | - | - |
| CRO_T015936 | AT2G03220 (0) | ATFT1|FUCOSYLTRANSFERASE 1; MUR2|MURUS 2 |
| CRO_T019333 | AT1G71190 (8.00E-82) | SAG18|senescence associated gene 18 |
| CRO_T022846 | AT2G47760 (4.00E-132) | ALG3|asparagine-linked glycosylation 3 |
| CRO_T025892 | AT5G07320 (1.00E-16) | APC3|ATP/phosphate carrier 3 |
| CRO_T026070 | AT1G07530 (2.00E-167) | ATGRAS2|GRAS (GAI, RGA, SCR) 2; SCL14|SCARECROW-like 14 |
| CRO_T026647 | AT1G28410 (1.00E-39) | unknown protein |
| CRO_T029702 | AT1G09010 (0) | glycoside hydrolase family 2 protein |
| CRO_T030679 | AT5G13950 (1.00E-109) | unknown protein |
| CRO_T030792 | AT1G55150 (2.00E-115) | RH20|RNA helicase 20 |
| CRO_T032485 | AT3G56750 (1.00E-146) | unknown protein |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TreatCFM001041 | NEDD8-specific protease activity structural constituent of cell wall ATP binding protein serine/threonine kinase activity Protein_kinases_phosphatases, PPC:1.6.2: Plant External Response Like Kinase Protein_kinases_phosphatases, PPC:4.2.4: SNF1 Related Protein Kinase (SnRK) Transcription_related, Transcription factor: Trihelix cullin deneddylation positive regulation of G2/M transition of mitotic cell cycle COP9 signalosome proteasome complex protein phosphorylation regulation of gene expression RNA secondary structure unwinding mRNA splicing, via spliceosome ATP-dependent RNA helicase activity | details |
| TreatCFM001393 | carbohydrate binding glucan 1,3-alpha-glucosidase activity aldose 1-epimerase activity L-amino acid transmembrane transporter activity solute:proton antiporter activity negative regulation of biological process L-alpha-amino acid transmembrane transport hexose metabolic process L-amino acid transport MicroRNAs in cancer early endosome membrane potassium ion transport Glycolysis / Gluconeogenesis N-Glycan biosynthesis SNARE binding SNAP receptor activity cellular macromolecule metabolic process antiporter activity primary metabolic process exocytosis vesicle fusion | details |
| TreatCFM001394 | benzoate biosynthesis III (CoA-dependent, non-β-oxidative) fatty acid α-oxidation I negative regulation of biological process L-alpha-amino acid transmembrane transport L-amino acid transport cellular aldehyde metabolic process mitochondrion organization integral component of mitochondrial outer membrane glucan 1,3-alpha-glucosidase activity aldehyde dehydrogenase [NAD(P)+] activity 3-chloroallyl aldehyde dehydrogenase activity MicroRNAs in cancer Mitophagy - animal L-amino acid transmembrane transporter activity Glycolysis / Gluconeogenesis cellular macromolecule metabolic process aldehyde dehydrogenase (NAD) activity N-Glycan biosynthesis primary metabolic process Ubiquitin_Proteasome_system, E3 adaptor: F-box small GTPase mediated signal transduction | details |
| TreatCFM001395 | MicroRNAs in cancer L-amino acid transmembrane transporter activity antiporter activity integral component of plasma membrane L-amino acid transport L-alpha-amino acid transmembrane transport hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc amino acid transmembrane transport hydrolase activity, acting on ester bonds | details |
| TreatCFM001396 | MicroRNAs in cancer L-amino acid transport L-alpha-amino acid transmembrane transport L-amino acid transmembrane transporter activity response to stress antiporter activity | details |
| TreatCFM001645 | hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc Protein_kinases_phosphatases, PPC:4.1.2: STE20-PAK Like Protein Kinase hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides mannosylglycoprotein endo-beta-mannosidase activity Fanconi anemia pathway interstrand cross-link repair receptor signaling protein serine/threonine kinase activity nuclease activity Transcription_related, Transcription factor: GRAS | details |
| TreatCFM001726 | L-phenylalanine biosynthesis II L-tyrosine biosynthesis II Transcription_related, Transcription factor: Whirly hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc MicroRNAs in cancer L-amino acid transport chorismate metabolic process L-alpha-amino acid transmembrane transport Ubiquitin_Proteasome_system, DUB: USP aromatic amino acid family biosynthetic process chorismate mutase activity defense response to fungus cellular protein metabolic process L-amino acid transmembrane transporter activity cysteine-type peptidase activity positive regulation of transcription, DNA-templated Biosynthesis of amino acids antiporter activity hydrolase activity, acting on ester bonds | details |
| TreatCFM001781 | Ras signaling pathway cytoskeletal part microtubule cytoskeleton cytokinesis by cell plate formation | details |
| TreatCFM001782 | translation initiation factor binding formation of translation preinitiation complex regulation of translational initiation eukaryotic 43S preinitiation complex eukaryotic translation initiation factor 3 complex eukaryotic 48S preinitiation complex translation initiation factor activity RNA transport Transcriptional misregulation in cancers microtubule cytoskeleton cytoskeletal part cytokinesis by cell plate formation Transcription_related, Transcription factor: FAR1 | details |
| TreatCFM001808 | xyloglucan biosynthesis calcium ion binding formation of glycosidic bonds, GlycosylTransferases: GTnc Proteasome calcium-dependent phospholipid binding helicase activity | details |
| TreatCFM001821 | mRNA splicing, via spliceosome Spliceosome Transcription_related, Transcription factor: Whirly MicroRNAs in cancer hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc DNA replication factor A complex L-amino acid transport L-alpha-amino acid transmembrane transport Ubiquitin_Proteasome_system, DUB: USP Prp19 complex Cul4-RING E3 ubiquitin ligase complex COPII vesicle coat Proteasome precatalytic spliceosome catalytic step 2 spliceosome defense response to fungus regulation of gene expression RNA secondary structure unwinding ER to Golgi vesicle-mediated transport cellular protein metabolic process positive regulation of transcription, DNA-templated | details |
| TreatCFM001962 | L-alpha-amino acid transmembrane transport L-amino acid transport hexose metabolic process MicroRNAs in cancer Thyroid hormone signaling pathway Glycolysis / Gluconeogenesis aldose 1-epimerase activity early endosome membrane L-amino acid transmembrane transporter activity Transcription_related, Transcription factor: MYB vesicle fusion exocytosis protein transport SNAP receptor activity SNARE binding antiporter activity carbohydrate binding | details |
| TreatCFM002074 | proteolysis L-alpha-amino acid transmembrane transport L-amino acid transport Ubiquitin_Proteasome_system, DUB: USP MicroRNAs in cancer cellular protein metabolic process cysteine-type peptidase activity L-amino acid transmembrane transporter activity metal ion binding aspartic-type endopeptidase activity antiporter activity | details |
| TreatCFM002088 | Spliceosome Protein_kinases_phosphatases, PPC:4.1.5.1: WNK like kinase - with no lysine kinase transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II core promoter proximal region sequence-specific DNA binding Transcription_related, Transcription factor: GRAS MAPK signaling pathway - plant spliceosomal complex | details |
| TreatCFM002136 | Ubiquitin_Proteasome_system, DUB: USP thiol oxidase activity Ras signaling pathway maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) cellular protein metabolic process cytoplasmic translation cysteine-type peptidase activity poly(A) RNA binding metal ion binding identical protein binding small GTPase mediated signal transduction | details |
Expression profiles
 Show details about module gene expression profiling |