TissueCFM001085's detailed annotation
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Protein: Yellow color--query protein Green color--interaction proteins. Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
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Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontolog |
|---|---|---|
| ceramide degradation | 0.003722194 | plantCyc |
| Transcription_related, Transcription factor: BBR-BPC | 0.003722194 | TF family |
| peptide-serine-N-acetyltransferase activity | 0.00449737 | GO:1990189 |
| D-erythro-sphingosine kinase activity | 0.00449737 | GO:0017050 |
| peptide-glutamate-N-acetyltransferase activity | 0.00449737 | GO:1990190 |
| positive regulation of histone methylation | 0.005148114 | GO:0031062 |
| N-terminal peptidyl-glutamic acid acetylation | 0.005148114 | GO:0018002 |
| N-terminal peptidyl-serine acetylation | 0.005148114 | GO:0017198 |
| internal protein amino acid acetylation | 0.005148114 | GO:0006475 |
| NatA complex | 0.00608174 | GO:0031415 |
| sphingolipid biosynthesis (plants) | 0.006505182 | plantCyc |
| sphingolipid biosynthetic process | 0.006862934 | GO:0030148 |
| regulation of RNA metabolic process | 0.006862934 | GO:0051252 |
| Transcription_related, Transcription regulator: GNAT | 0.008050466 | TF family |
| system development | 0.008822208 | GO:0048731 |
| regulation of shoot system development | 0.009005206 | GO:0048831 |
| cytosolic ribosome | 0.013164258 | GO:0022626 |
| clathrin adaptor complex | 0.013164258 | GO:0030131 |
| phospholipid-translocating ATPase activity | 0.013481348 | GO:0004012 |
| phospholipid translocation | 0.013716136 | GO:0045332 |
| regulation of gene expression | 0.019533368 | GO:0010468 |
| Endocytosis | 0.020507301 | KEGG pathway |
| plasma membrane | 0.028448628 | GO:0005886 |
| response to stimulus | 0.038244392 | GO:0050896 |
| single-organism cellular process | 0.040166338 | GO:0044763 |
| protein transporter activity | 0.045678395 | GO:0008565 |
Module member annotation
| Gene ID | Ortholog in Arabidopsis (Blast E-value) | Annotation in Arabidopsis |
|---|---|---|
| CRO_T009118 | AT1G03150 (1.00E-23) | Acyl-CoA N-acyltransferases (NAT) superfamily protein |
| CRO_T017030 | AT3G50590 (2.00E-91) | Transducin/WD40 repeat-like superfamily protein |
| CRO_T021068 | AT5G55390 (2.00E-108) | EDM2|ENHANCED DOWNY MILDEW 2 |
| CRO_T024675 | AT5G44240 (0) | ALA2|aminophospholipid ATPase 2 |
| CRO_T028758 | AT5G23450 (6.00E-34) | ATLCBK1|long-chain base (LCB) kinase 1 |
| CRO_T029282 | AT1G14685 (2.00E-78) | ATBPC2|BASIC PENTACYSTEINE 2 |
| CRO_T032704 | AT1G23900 (5.00E-31) | GAMMA-ADAPTIN 1|gamma-adaptin 1; Gamma-ADR|Gamma-adaptin |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TissueCFM000055 | molybdenum cofactor biosynthesis | details |
| TissueCFM000075 | methylerythritol phosphate pathway II methylerythritol phosphate pathway I Terpenoid backbone biosynthesis secologanin and strictosidine biosynthesis terpenoid biosynthetic process isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway oxidation-reduction process monoterpenoid biosynthetic process geraniol and geranial biosynthesis acetaldehyde biosynthesis I pyruvate fermentation to ethanol II Transcription_related, Transcription factor: bHLH heme binding iron ion binding (3S)-linalool biosynthesis formaldehyde oxidation II (glutathione-dependent) geranyl diphosphate biosynthesis isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process steroid hormone mediated signaling pathway geranyl diphosphate metabolic process | details |
| TissueCFM000127 | Transcription_related, Transcription factor: BBR-BPC integral component of lumenal side of endoplasmic reticulum membrane Golgi-associated vesicle membrane integral component of cytoplasmic side of endoplasmic reticulum membrane lysosomal membrane ribonucleoside-diphosphate reductase complex membrane protein proteolysis signal peptide processing pollen germination deoxyribonucleotide biosynthetic process aspartic endopeptidase activity, intramembrane cleaving ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor | details |
| TissueCFM000253 | peptide-serine-N-acetyltransferase activity peptide-glutamate-N-acetyltransferase activity N-terminal peptidyl-glutamic acid acetylation internal protein amino acid acetylation N-terminal peptidyl-serine acetylation NatA complex Transcription_related, Transcription regulator: GNAT cytosolic ribosome | details |
| TissueCFM000264 | NatA complex N-terminal peptidyl-serine acetylation N-terminal peptidyl-glutamic acid acetylation internal protein amino acid acetylation peptide-serine-N-acetyltransferase activity peptide-glutamate-N-acetyltransferase activity Transcription_related, Transcription regulator: GNAT cytosolic ribosome RNA binding ARF guanyl-nucleotide exchange factor activity spliceosomal complex regulation of ARF protein signal transduction ribonuclease III activity MicroRNAs in cancer RNA phosphodiester bond hydrolysis, endonucleolytic positive regulation of GTPase activity RNA processing mRNA splicing, via spliceosome RNA degradation | details |
| TissueCFM000405 | N-terminal peptidyl-serine acetylation N-terminal peptidyl-glutamic acid acetylation internal protein amino acid acetylation NatA complex peptide-serine-N-acetyltransferase activity peptide-glutamate-N-acetyltransferase activity Glucagon signaling pathway cytosolic ribosome Transcription_related, Transcription regulator: GNAT ATP-dependent helicase activity RNA degradation | details |
| TissueCFM000542 | Glucagon signaling pathway N-terminal peptidyl-serine acetylation N-terminal peptidyl-glutamic acid acetylation internal protein amino acid acetylation peptide-glutamate-N-acetyltransferase activity peptide-serine-N-acetyltransferase activity negative regulation of nucleic acid-templated transcription transcription corepressor activity NatA complex Transcription_related, Transcription regulator: GNAT cytosolic ribosome | details |
| TissueCFM000576 | Transcription_related, Transcription factor: BBR-BPC | details |
| TissueCFM000683 | Transcription_related, Transcription factor: BBR-BPC | details |
| TissueCFM000747 | peptide-serine-N-acetyltransferase activity NatB complex NatA complex peptide-glutamate-N-acetyltransferase activity N-terminal peptidyl-glutamic acid acetylation N-terminal peptidyl-serine acetylation internal protein amino acid acetylation N-terminal peptidyl-methionine acetylation DNA topoisomerase type I activity cellular component organization reproductive structure development DNA topological change Transcription_related, Transcription regulator: TRAF Ubiquitin_Proteasome_system, SOCS/VHL/BC-box: 3-box Transcription_related, Transcription regulator: GNAT cytosolic ribosome single organism reproductive process peptide alpha-N-acetyltransferase activity post-embryonic development hydroquinone:oxygen oxidoreductase activity lignin catabolic process Ubiquitin_Proteasome_system, E3 adaptor: BTB Regulation of actin cytoskeleton single-organism cellular process Homologous recombination Ubiquitin mediated proteolysis | details |
| TissueCFM001061 | D-myo-inositol (1,4,5)-trisphosphate degradation peptide-serine-N-acetyltransferase activity peptide-glutamate-N-acetyltransferase activity internal protein amino acid acetylation N-terminal peptidyl-serine acetylation N-terminal peptidyl-glutamic acid acetylation NatA complex voltage-gated chloride channel activity Protein_kinases_phosphatases, PPC:3.1.1: Casein Kinase I Family Transcription_related, Transcription regulator: GNAT phosphatidylinositol dephosphorylation chloride transport Wnt signaling pathway regulation of cell shape regulation of anion transmembrane transport cytosolic ribosome Endocytosis hyperosmotic salinity response ion transmembrane transport peptidyl-serine phosphorylation Protein processing in endoplasmic reticulum | details |
| TissueCFM001066 | N-terminal peptidyl-glutamic acid acetylation positive regulation of transcription from RNA polymerase I promoter internal protein amino acid acetylation N-terminal peptidyl-serine acetylation N-terminal peptidyl-methionine acetylation t-UTP complex NatB complex NatA complex peptide-glutamate-N-acetyltransferase activity peptide-serine-N-acetyltransferase activity cytosolic ribosome 90S preribosome Transcription_related, Transcription regulator: GNAT spliceosomal complex peptide alpha-N-acetyltransferase activity snoRNA binding hydroquinone:oxygen oxidoreductase activity lignin catabolic process Autophagy - yeast maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) mRNA splicing, via spliceosome small-subunit processome Ribosome biogenesis in eukaryotes | details |
| TissueCFM001067 | N-terminal peptidyl-glutamic acid acetylation internal protein amino acid acetylation N-terminal peptidyl-serine acetylation peptide-glutamate-N-acetyltransferase activity peptide-serine-N-acetyltransferase activity NatA complex cytosolic ribosome spliceosomal complex Transcription_related, Transcription regulator: GNAT mRNA splicing, via spliceosome Spliceosome | details |
| TissueCFM001199 | D-myo-inositol (1,4,5)-trisphosphate degradation Transcription_related, Transcription factor: SBP Transcription_related, Transcription regulator: GNAT peptide-serine-N-acetyltransferase activity peptide-glutamate-N-acetyltransferase activity long-day photoperiodism N-terminal peptidyl-serine acetylation N-terminal peptidyl-glutamic acid acetylation stem cell fate determination internal protein amino acid acetylation meristem maintenance cellular calcium ion homeostasis nuclear-transcribed mRNA catabolic process, nonsense-mediated decay pollen maturation NatA complex sugar mediated signaling pathway phosphatidylinositol dephosphorylation cellular response to phosphate starvation pollen germination response to wounding nucleic acid metabolic process cellular macromolecule metabolic process cation transmembrane transport salicylic acid mediated signaling pathway jasmonic acid mediated signaling pathway cation-transporting ATPase activity | details |
| TissueCFM001250 | Aminoacyl-tRNA biosynthesis Alzheimer's disease Transcription_related, Transcription factor: BBR-BPC mitochondrial alanyl-tRNA aminoacylation isoleucyl-tRNA aminoacylation peptide catabolic process regulation of translational fidelity Cul3-RING ubiquitin ligase complex alanine-tRNA ligase activity isoleucine-tRNA ligase activity mitochondrion cytosol aminoacyl-tRNA editing activity tRNA binding tRNA modification protein processing zinc ion binding metalloendopeptidase activity amino acid binding proteolysis involved in cellular protein catabolic process | details |
| TissueCFM001326 | formation of glycosidic bonds, GlycosylTransferases: GTnc Transcription_related, Transcription factor: BBR-BPC regulation of biological process folic acid-containing compound biosynthetic process | details |
| TissueCFM001371 | actin binding N-terminal peptidyl-glutamic acid acetylation internal protein amino acid acetylation N-terminal peptidyl-serine acetylation peptide-serine-N-acetyltransferase activity peptide-glutamate-N-acetyltransferase activity NatA complex phosphatidylinositol-mediated signaling cytoskeleton organization Transcription_related, Transcription regulator: GNAT Ubiquitin_Proteasome_system, DUB: USP 1-phosphatidylinositol 4-kinase activity DNA topoisomerase type I activity 3-phosphoinositide biosynthesis D-myo-inositol (1,4,5)-trisphosphate biosynthesis motor activity myosin complex cytosolic ribosome spliceosomal complex phosphatidylinositol phosphorylation single-organism process mRNA splicing, via spliceosome Inositol phosphate metabolism | details |
| TissueCFM001448 | Protein processing in endoplasmic reticulum internal protein amino acid acetylation N-terminal peptidyl-glutamic acid acetylation N-terminal peptidyl-serine acetylation peptide-serine-N-acetyltransferase activity peptide-glutamate-N-acetyltransferase activity NatA complex Golgi apparatus part Transcription_related, Transcription regulator: GNAT Ubiquitin_Proteasome_system, E3 adaptor: Cullin intracellular transport cytosolic ribosome cullin-RING ubiquitin ligase complex COPII vesicle coat vacuolar transport mRNA surveillance pathway ER to Golgi vesicle-mediated transport protein ubiquitination involved in ubiquitin-dependent protein catabolic process vesicle-mediated transport | details |
| TissueCFM001449 | phosphatidylethanolamine biosynthesis I FoxO signaling pathway Protein digestion and absorption Ubiquitin_Proteasome_system, DUB: ULP Ubiquitin_Proteasome_system, DUB: USP Ubiquitin_Proteasome_system, E3: HECT very long chain fatty acid biosynthesis I Glycerophospholipid metabolism | details |
| TissueCFM001451 | phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity peptide-serine-N-acetyltransferase activity peptide-glutamate-N-acetyltransferase activity Golgi apparatus recycling endosome NatA complex Rab guanyl-nucleotide exchange factor activity N-terminal peptidyl-serine acetylation N-terminal peptidyl-glutamic acid acetylation internal protein amino acid acetylation Transcription_related, Transcription regulator: GNAT NuA4 histone acetyltransferase complex 3-phosphoinositide biosynthesis phosphatidylinositol-3-phosphate biosynthetic process cytosolic ribosome cytoskeleton organization plant-type cell wall biogenesis hyperosmotic salinity response unidimensional cell growth positive regulation of GTPase activity protein serine/threonine phosphatase activity mRNA surveillance pathway | details |
| TissueCFM001484 | peptide-glutamate-N-acetyltransferase activity peptide-serine-N-acetyltransferase activity NatA complex N-terminal peptidyl-serine acetylation internal protein amino acid acetylation N-terminal peptidyl-glutamic acid acetylation Transcription_related, Transcription regulator: DDT protein monoubiquitination histone ubiquitination innate immune response HAUS complex cytosolic ribosome reproductive structure development spindle assembly Transcription_related, Transcription regulator: GNAT post-embryonic development single-organism cellular process Protein processing in endoplasmic reticulum | details |
| TissueCFM001510 | cellular response to stress positive regulation of kinase activity UDP-glucosylation glucan 1,4-alpha-maltotetraohydrolase activity UDP-glucose:glycoprotein glucosyltransferase activity regulation of translation formation of glycosidic bonds, GlycosylTransferases: GTnc alpha-amylase activity regulation of protein kinase activity Transcription_related, Transcription factor: BBR-BPC protein kinase regulator activity hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc protein kinase binding ribosome binding protein glycosylation Transcription_related, Transcription regulator: SNF2 RNA degradation | details |
| TissueCFM001601 | peptide-serine-N-acetyltransferase activity peptide-glutamate-N-acetyltransferase activity N-terminal peptidyl-glutamic acid acetylation internal protein amino acid acetylation N-terminal peptidyl-serine acetylation cellulose biosynthesis NatA complex Autophagy - yeast cytosolic ribosome spliceosomal complex plasma membrane zinc ion binding cellulose synthase (UDP-forming) activity recognition of pollen formation of glycosidic bonds, GlycosylTransferases: GTnc Protein_kinases_phosphatases, PPC:1.9.2: S Domain Kinase (Type 2) Transcription_related, Transcription regulator: GNAT cellulose biosynthetic process mRNA splicing, via spliceosome Spliceosome | details |
| TissueCFM001673 | N-terminal peptidyl-serine acetylation N-terminal peptidyl-glutamic acid acetylation internal protein amino acid acetylation Transcription_related, Transcription regulator: GNAT long-day photoperiodism peptide-serine-N-acetyltransferase activity peptide-glutamate-N-acetyltransferase activity NatA complex nuclear-transcribed mRNA catabolic process, nonsense-mediated decay G-protein beta/gamma-subunit complex binding G-protein coupled receptor signaling pathway sugar mediated signaling pathway response to wounding salicylic acid mediated signaling pathway cytoplasmic mRNA processing body cytosolic ribosome spliceosomal complex jasmonic acid mediated signaling pathway mRNA splicing, via spliceosome defense response to bacterium signal transducer activity | details |
Expression profiles
 Show details about module gene expression profiling |