TissueCFM001254's detailed annotation
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Protein: Yellow color--query protein Green color--interaction proteins. Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
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Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontolog |
|---|---|---|
| ARF guanyl-nucleotide exchange factor activity | 1.36E-07 | GO:0005086 |
| regulation of ARF protein signal transduction | 1.52E-07 | GO:0032012 |
| positive regulation of GTPase activity | 8.92E-06 | GO:0043547 |
| formation of glycosidic bonds, GlycosylTransferases: GTnc | 0.000709084 | cazy family |
| UDP-glucosylation | 0.003772176 | GO:0097359 |
| negative regulation of protein kinase activity | 0.003772176 | GO:0006469 |
| attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation | 0.003772176 | GO:0051455 |
| tetracyclic triterpenoid biosynthetic process | 0.003772176 | GO:0010686 |
| meiotic sister chromatid cohesion, centromeric | 0.003772176 | GO:0051754 |
| protein kinase inhibitor activity | 0.007851601 | GO:0004860 |
| UDP-glucose:glycoprotein glucosyltransferase activity | 0.007851601 | GO:0003980 |
| isoleucyl-tRNA aminoacylation | 0.008247612 | GO:0006428 |
| cycloartenol synthase activity | 0.011773573 | GO:0016871 |
| mangrove triterpenoid biosynthesis | 0.013623268 | plantCyc |
| plant sterol biosynthesis II | 0.013623268 | plantCyc |
| isoleucine-tRNA ligase activity | 0.01372914 | GO:0004822 |
| double-stranded RNA binding | 0.01372914 | GO:0003725 |
| carboxypeptidase activity | 0.015125156 | GO:0004180 |
| aminoacyl-tRNA editing activity | 0.016170258 | GO:0002161 |
| regulation of translational fidelity | 0.017574903 | GO:0006450 |
| protein kinase binding | 0.019587578 | GO:0019901 |
| plant sterol biosynthesis | 0.020055085 | plantCyc |
| protein glycosylation | 0.042042966 | GO:0006486 |
Module member annotation
| Gene ID | Ortholog in Arabidopsis (Blast E-value) | Annotation in Arabidopsis |
|---|---|---|
| CRO_T001678 | AT1G66960 (0) | LUP5|Terpenoid cyclases family protein |
| CRO_T002076 | AT1G35220 (8.00E-126) | unknown protein |
| CRO_T002870 | AT3G43300 (0) | ATMIN7|HOPM interactor 7; BEN1|BFA-VISUALIZED ENDOCYTIC TRAFFICKING DEFECTIVE1 |
| CRO_T004665 | AT2G47980 (0) | ATSCC3|SISTER-CHROMATID COHESION PROTEIN 3 |
| CRO_T006011 | AT4G10320 (7.00E-159) | tRNA synthetase class I (I, L, M and V) family protein |
| CRO_T009865 | AT1G01960 (0) | EDA10|embryo sac development arrest 10 |
| CRO_T013404 | AT3G24530 (7.00E-11) | AAA-type ATPase family protein / ankyrin repeat family protein |
| CRO_T018365 | AT3G60860 (3.00E-18) | SEC7-like guanine nucleotide exchange family protein |
| CRO_T023198 | AT1G71220 (0) | EBS1|EMS-mutagenized bri1 suppressor 1; PSL2|PRIORITY IN SWEET LIFE 2; UGGT|UDP-GLUCOSE:GLYCOPROTEIN GLUCOSYLTRANSFERASE |
| CRO_T027165 | AT1G79390 (1.00E-48) | unknown protein |
| CRO_T028357 | AT2G15270 (1.00E-26) | unknown protein |
| CRO_T033553 | AT3G62360 (0) | Carbohydrate-binding-like fold |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TissueCFM000231 | Other glycan degradation cellulose biosynthesis negative regulation of protein kinase activity protein kinase inhibitor activity formation of glycosidic bonds, GlycosylTransferases: GTnc Protein_kinases_phosphatases, PPC:2.1.4: GmPK6/AtMRK1 Family mannose metabolic process protein deglycosylation alpha-mannosidase activity double-stranded RNA binding protein kinase binding cellulose synthase (UDP-forming) activity cellulose biosynthetic process | details |
| TissueCFM000264 | NatA complex N-terminal peptidyl-serine acetylation N-terminal peptidyl-glutamic acid acetylation internal protein amino acid acetylation peptide-serine-N-acetyltransferase activity peptide-glutamate-N-acetyltransferase activity Transcription_related, Transcription regulator: GNAT cytosolic ribosome RNA binding ARF guanyl-nucleotide exchange factor activity spliceosomal complex regulation of ARF protein signal transduction ribonuclease III activity MicroRNAs in cancer RNA phosphodiester bond hydrolysis, endonucleolytic positive regulation of GTPase activity RNA processing mRNA splicing, via spliceosome RNA degradation | details |
| TissueCFM000457 | negative regulation of protein kinase activity protein kinase inhibitor activity peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity double-stranded RNA binding recognition of pollen Transcription_related, Transcription regulator: SWI/SNF-BAF60b protein kinase binding Protein_kinases_phosphatases, PPC:1.9.2: S Domain Kinase (Type 2) lipid binding | details |
| TissueCFM000477 | protein retention in Golgi apparatus negative regulation of protein kinase activity intracellular protein transport meiotic cell cycle shoot system morphogenesis double-strand break repair euchromatin Mre11 complex Protein_kinases_phosphatases, PPC:1.16.1: Receptor Like Cytoplasmic Kinase II Transcription_related, Transcription factor: G2-like Ubiquitin_Proteasome_system, DUB: ULP Ubiquitin_Proteasome_system, DUB: USP synaptonemal complex retromer complex protein kinase inhibitor activity Golgi transport complex FoxO signaling pathway meristem structural organization Golgi organization retrograde vesicle-mediated transport, Golgi to ER cell growth retrograde transport, endosome to Golgi protein deubiquitination double-stranded RNA binding thiol-dependent ubiquitinyl hydrolase activity protein kinase binding manganese ion binding 3'-5' exonuclease activity endonuclease activity | details |
| TissueCFM000630 | cellulose biosynthesis cellulose synthase (UDP-forming) activity cellulose biosynthetic process cell wall organization mRNA surveillance pathway carbohydrate homeostasis negative regulation of protein kinase activity sulfate transport cellular response to sucrose stimulus embryonic root morphogenesis protein dephosphorylation L-arabinose metabolic process plant-type primary cell wall biogenesis calcium ion transport osmosensory signaling pathway | details |
| TissueCFM001116 | Homologous recombination negative regulation of protein kinase activity double-strand break repair meiotic cell cycle isoleucyl-tRNA aminoacylation Mre11 complex euchromatin synaptonemal complex pseudouridine synthesis regulation of translational fidelity DNA topoisomerase activity protein kinase inhibitor activity double-stranded RNA binding isoleucine-tRNA ligase activity protein kinase binding aminoacyl-tRNA editing activity pseudouridine synthase activity Aminoacyl-tRNA biosynthesis manganese ion binding endonuclease activity 3'-5' exonuclease activity nucleic acid phosphodiester bond hydrolysis | details |
| TissueCFM001250 | Aminoacyl-tRNA biosynthesis Alzheimer's disease Transcription_related, Transcription factor: BBR-BPC mitochondrial alanyl-tRNA aminoacylation isoleucyl-tRNA aminoacylation peptide catabolic process regulation of translational fidelity Cul3-RING ubiquitin ligase complex alanine-tRNA ligase activity isoleucine-tRNA ligase activity mitochondrion cytosol aminoacyl-tRNA editing activity tRNA binding tRNA modification protein processing zinc ion binding metalloendopeptidase activity amino acid binding proteolysis involved in cellular protein catabolic process | details |
| TissueCFM001346 | Ribosome biogenesis in eukaryotes preribosome isoleucyl-tRNA aminoacylation regulation of translational fidelity aminoacyl-tRNA editing activity isoleucine-tRNA ligase activity ribosome biogenesis Aminoacyl-tRNA biosynthesis formation of glycosidic bonds, GlycosylTransferases: GTnc | details |
| TissueCFM001391 | abscisic acid biosynthesis Transcription_related, Transcription regulator: SNF2 base-excision repair oxalate metabolic process DNA-3-methyladenine glycosylase activity nutrient reservoir activity oxalate decarboxylase activity small GTPase mediated signal transduction manganese ion binding Base excision repair Homologous recombination Endocytosis | details |
| TissueCFM001491 | Spliceosome U5 snRNA binding pre-mRNA intronic binding U2 snRNA binding U6 snRNA binding second spliceosomal transesterification activity queuine tRNA-ribosyltransferase activity U1 snRNA binding ARF guanyl-nucleotide exchange factor activity spliceosomal tri-snRNP complex assembly queuosine biosynthetic process regulation of ARF protein signal transduction ubiquitin binding poly(A) RNA binding catalytic step 2 spliceosome ubiquitin ligase complex viral nucleocapsid U5 snRNP intracellular ribonucleoprotein complex Cysteine and methionine metabolism cytoplasm | details |
| TissueCFM001510 | cellular response to stress positive regulation of kinase activity UDP-glucosylation glucan 1,4-alpha-maltotetraohydrolase activity UDP-glucose:glycoprotein glucosyltransferase activity regulation of translation formation of glycosidic bonds, GlycosylTransferases: GTnc alpha-amylase activity regulation of protein kinase activity Transcription_related, Transcription factor: BBR-BPC protein kinase regulator activity hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc protein kinase binding ribosome binding protein glycosylation Transcription_related, Transcription regulator: SNF2 RNA degradation | details |
| TissueCFM001512 | 1,3-β-D-glucan biosynthesis formation of glycosidic bonds, GlycosylTransferases: GTnc nuclear pore inner ring microtubule organizing center cellular component assembly cell cycle process microtubule cytoskeleton organization double-strand break repair via homologous recombination (1->3)-beta-D-glucan biosynthetic process nuclear pore organization protein import into nucleus, docking regulation of ARF protein signal transduction 1,3-beta-D-glucan synthase complex ARF guanyl-nucleotide exchange factor activity 1,3-beta-D-glucan synthase activity structural constituent of nuclear pore Transcription_related, Transcription regulator: SNF2 positive regulation of GTPase activity RNA transport organic cyclic compound binding heterocyclic compound binding | details |
| TissueCFM001513 | negative regulation of protein kinase activity isoleucyl-tRNA aminoacylation regulation of translational fidelity protein kinase inhibitor activity double-stranded RNA binding isoleucine-tRNA ligase activity aminoacyl-tRNA editing activity protein kinase binding Aminoacyl-tRNA biosynthesis | details |
| TissueCFM001618 | attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation negative regulation of protein kinase activity meiotic sister chromatid cohesion, centromeric isoleucyl-tRNA aminoacylation regulation of translational fidelity isoleucine-tRNA ligase activity Rab guanyl-nucleotide exchange factor activity double-stranded RNA binding protein kinase inhibitor activity carboxypeptidase activity aminoacyl-tRNA editing activity recycling endosome protein kinase binding Aminoacyl-tRNA biosynthesis Cell cycle positive regulation of GTPase activity carbohydrate binding | details |
| TissueCFM001619 | Alzheimer's disease recycling endosome Cul3-RING ubiquitin ligase complex regulation of DNA-templated transcription, elongation isoleucyl-tRNA aminoacylation peptide catabolic process Rab guanyl-nucleotide exchange factor activity isoleucine-tRNA ligase activity nucleobase-containing compound metabolic process regulation of translational fidelity aminoacyl-tRNA editing activity Aminoacyl-tRNA biosynthesis protein processing positive regulation of GTPase activity regulation of transcription from RNA polymerase II promoter proteolysis involved in cellular protein catabolic process Ubiquitin_Proteasome_system, E3 adaptor: F-box metalloendopeptidase activity | details |
| TissueCFM001707 | isoleucyl-tRNA aminoacylation regulation of translational fidelity aminoacyl-tRNA editing activity isoleucine-tRNA ligase activity Aminoacyl-tRNA biosynthesis | details |
| TissueCFM001828 | histone ubiquitination innate immune response protein monoubiquitination reproductive structure development regulation of ARF protein signal transduction post-embryonic development ARF guanyl-nucleotide exchange factor activity single-organism cellular process positive regulation of GTPase activity viral nucleocapsid intracellular ribonucleoprotein complex vesicle-mediated transport | details |
Expression profiles
 Show details about module gene expression profiling |