TissueCFM001670's detailed annotation
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Protein: Yellow color--query protein Green color--interaction proteins. Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
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Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontolog |
|---|---|---|
| regulation of ruffle assembly | 0.003447087 | GO:1900027 |
| lysyl-tRNA aminoacylation | 0.003447087 | GO:0006430 |
| sphingolipid biosynthesis (plants) | 0.004336788 | plantCyc |
| ruffle membrane | 0.005171089 | GO:0032587 |
| Sphingolipid metabolism | 0.01177337 | KEGG pathway |
| Transcription_related, Transcription factor: C2H2 | 0.016026902 | TF family |
| Aminoacyl-tRNA biosynthesis | 0.019749902 | KEGG pathway |
| lysine-tRNA ligase activity | 0.021063672 | GO:0004824 |
| nucleic acid binding | 0.026031955 | GO:0003676 |
| fatty acid biosynthetic process | 0.038278117 | GO:0006633 |
| phosphatidylinositol binding | 0.038555153 | GO:0035091 |
Module member annotation
| Gene ID | Ortholog in Arabidopsis (Blast E-value) | Annotation in Arabidopsis |
|---|---|---|
| CRO_T007096 | AT2G31130 (4.00E-21) | unknown protein |
| CRO_T014819 | - | - |
| CRO_T015787 | AT3G11710 (8.00E-180) | ATKRS-1|lysyl-tRNA synthetase 1 |
| CRO_T019188 | AT1G69640 (1.00E-112) | SBH1|sphingoid base hydroxylase 1 |
| CRO_T025616 | AT1G33490 (1.00E-47) | unknown protein |
| CRO_T026130 | - | - |
| CRO_T031101 | AT5G48650 (2.00E-22) | Nuclear transport factor 2 (NTF2) family protein with RNA binding (RRM-RBD-RNP motifs) domain |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TissueCFM000108 | lysyl-tRNA aminoacylation plasmodesma lysine-tRNA ligase activity single-organism metabolic process phosphatidylcholine acyl editing phospholipases phospholipid remodeling (phosphatidylcholine, yeast) cytosol Peroxisome Aminoacyl-tRNA biosynthesis Ubiquitin_Proteasome_system, E3 adaptor: DWD | details |
| TissueCFM000416 | hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc endoplasmic reticulum lysyl-tRNA aminoacylation sucrose alpha-glucosidase activity glycopeptide alpha-N-acetylgalactosaminidase activity lysine-tRNA ligase activity phosphorelay sensor kinase activity phosphorelay signal transduction system signal transduction by protein phosphorylation | details |
| TissueCFM000489 | lysyl-tRNA aminoacylation flavin-containing compound metabolic process FAD diphosphatase activity lysine-tRNA ligase activity Transcription_related, Transcription factor: FAR1 nucleic acid binding phosphatase activity | details |
| TissueCFM000635 | S-methyl-5-thio-α-D-ribose 1-phosphate degradation adenine import across plasma membrane hypoxanthine transport guanine import across plasma membrane uracil import across plasma membrane L-methionine biosynthetic process from S-adenosylmethionine ubiquinone biosynthetic process adenine transmembrane transporter activity uracil transmembrane transporter activity solute:cation symporter activity guanine transmembrane transporter activity L-methionine biosynthetic process from methylthioadenosine Cysteine and methionine metabolism cation transmembrane transport S-methyl-5-thioribose-1-phosphate isomerase activity Ubiquitin_Proteasome_system, DUB: OTU formation of glycosidic bonds, GlycosylTransferases: GTnc microtubule-based movement | details |
| TissueCFM001087 | nucleic acid binding amino acid homeostasis amino acid export amino acid import lysyl-tRNA aminoacylation lysine-tRNA ligase activity maturation of 5.8S rRNA spliceosomal complex assembly maturation of LSU-rRNA amino acid transmembrane transport amino acid transmembrane transporter activity Aminoacyl-tRNA biosynthesis catalytic step 2 spliceosome preribosome, large subunit precursor U2-type prespliceosome U2 snRNP | details |
| TissueCFM001177 | lysyl-tRNA aminoacylation Mo-molybdopterin cofactor biosynthetic process molybdenum cofactor biosynthesis molybdopterin synthase complex lysine-tRNA ligase activity Aminoacyl-tRNA biosynthesis RNA transport | details |
| TissueCFM001526 | CA1P biosynthesis TNF signaling pathway lysyl-tRNA aminoacylation lysine-tRNA ligase activity phosphoglycerate mutase activity plant sterol biosynthesis Transcription_related, Transcription factor: G2-like cytosol phosphatase activity Aminoacyl-tRNA biosynthesis protein folding dephosphorylation | details |
| TissueCFM001527 | benzoate biosynthesis III (CoA-dependent, non-β-oxidative) CA1P biosynthesis fatty acid α-oxidation I TNF signaling pathway lysyl-tRNA aminoacylation 3-chloroallyl aldehyde dehydrogenase activity lysine-tRNA ligase activity phosphoglycerate mutase activity aldehyde dehydrogenase (NAD) activity phosphatase activity Glycolysis / Gluconeogenesis cytosol Aminoacyl-tRNA biosynthesis single-organism metabolic process dephosphorylation protein folding unfolded protein binding | details |
| TissueCFM001671 | lysyl-tRNA aminoacylation regulation of ruffle assembly ruffle membrane tRNA processing lysine-tRNA ligase activity nucleic acid binding Transcription_related, Transcription factor: C2H2 rRNA processing Aminoacyl-tRNA biosynthesis Ribosome biogenesis in eukaryotes phosphatidylinositol binding | details |
| TissueCFM001702 | adenosine ribonucleotides de novo biosynthesis regulation of translation lysyl-tRNA aminoacylation lysine-tRNA ligase activity nucleic acid binding spliceosomal complex assembly response to cold mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) ATP hydrolysis coupled proton transport response to heat U2 snRNP U2-type prespliceosome pollen tube ATP synthesis coupled proton transport proton-transporting ATP synthase activity, rotational mechanism catalytic step 2 spliceosome | details |
| TissueCFM001713 | phospholipid desaturation lysyl-tRNA aminoacylation Transcription_related, Transcription factor: C2H2 lysine-tRNA ligase activity nucleic acid binding Aminoacyl-tRNA biosynthesis Ribosome biogenesis in eukaryotes tRNA processing rRNA processing chloroplast inner membrane | details |
Expression profiles
 Show details about module gene expression profiling |