TissueCFM001579's detailed annotation
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Protein: Yellow color--query protein Green color--interaction proteins. Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
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Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontolog |
|---|---|---|
| Transcription_related, Transcription factor: BBR-BPC | 0.004784688 | TF family |
| Transcription_related, Transcription factor: NF-YC | 0.00557686 | TF family |
| L-valine degradation I | 0.006630494 | plantCyc |
| RIG-I-like receptor signaling pathway | 0.015504101 | KEGG pathway |
| phosphoprotein binding | 0.024212331 | GO:0051219 |
| malonate-semialdehyde dehydrogenase (acetylating) activity | 0.026195941 | GO:0018478 |
| methylmalonate-semialdehyde dehydrogenase (acylating) activity | 0.026195941 | GO:0004491 |
| receptor activity | 0.026195941 | GO:0004872 |
| abscisic acid binding | 0.026195941 | GO:0010427 |
| protein phosphatase inhibitor activity | 0.026195941 | GO:0004864 |
| aldehyde dehydrogenase (NAD) activity | 0.029348605 | GO:0004029 |
| glutathione metabolic process | 0.047995427 | GO:0006749 |
| abscisic acid-activated signaling pathway | 0.047995427 | GO:0009738 |
| RNA secondary structure unwinding | 0.047995427 | GO:0010501 |
| regulation of protein serine/threonine phosphatase activity | 0.047995427 | GO:0080163 |
| negative regulation of catalytic activity | 0.047995427 | GO:0043086 |
| Glutathione metabolism | 0.049611342 | KEGG pathway |
Module member annotation
| Gene ID | Ortholog in Arabidopsis (Blast E-value) | Annotation in Arabidopsis |
|---|---|---|
| CRO_T000091 | AT1G02920 (2.00E-06) | ATGST11|ARABIDOPSIS GLUTATHIONE S-TRANSFERASE 11; GST11|GLUTATHIONE S-TRANSFERASE 11; GSTF7|glutathione S-transferase 7 |
| CRO_T005969 | AT5G23390 (0) | Plant protein of unknown function (DUF639) |
| CRO_T009496 | AT3G48590 (2.00E-63) | NF-YC1|nuclear factor Y, subunit C1 |
| CRO_T010334 | AT1G68120 (6.00E-33) | BPC3|basic pentacysteine 3 |
| CRO_T015313 | AT2G37080 (3.00E-112) | RIP2|ROP interactive partner 2 |
| CRO_T016138 | AT1G01360 (6.00E-79) | PYL9|PYRABACTIN RESISTANCE 1-LIKE 9; RCAR1|regulatory component of ABA receptor 1 |
| CRO_T017141 | AT2G14170 (0) | ALDH6B2|aldehyde dehydrogenase 6B2 |
| CRO_T030288 | AT4G25310 (6.00E-57) | 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein |
| CRO_T032746 | AT3G58570 (2.00E-121) | P-loop containing nucleoside triphosphate hydrolases superfamily protein |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TissueCFM000079 | Transcription_related, Transcription factor: NF-YC plasma membrane vesicle response to sucrose negative regulation of cell aging regulation of nucleic acid-templated transcription negative regulation of flower development protein targeting to vacuole vegetative to reproductive phase transition of meristem transcription cofactor activity transmembrane transporter activity protein heterodimerization activity | details |
| TissueCFM000145 | Transcription_related, Transcription factor: NF-YC Cell cycle - Caulobacter chloroplast stroma | details |
| TissueCFM000186 | Transcription_related, Transcription factor: NF-YC large ribosomal subunit intracellular ribonucleoprotein complex intracellular organelle | details |
| TissueCFM000334 | Transcription_related, Transcription factor: NF-YC ajmaline and sarpagine biosynthesis Starch and sucrose metabolism | details |
| TissueCFM000352 | serine family amino acid biosynthetic process formate catabolic process Hedgehog signaling pathway transferase activity, transferring phosphorus-containing groups phosphoglycerate dehydrogenase activity formate dehydrogenase (NAD+) activity Transcription_related, Transcription factor: NF-YC Transcription_related, Transcription factor: Orphans Ubiquitin_Proteasome_system, E3 adaptor: BTB signal transduction NAD binding protein heterodimerization activity | details |
| TissueCFM000411 | Transcription_related, Transcription factor: NF-YC Cell cycle - Caulobacter protein heterodimerization activity serine-type endopeptidase activity proteolysis | details |
| TissueCFM000435 | DNA recombination DNA integration Transcription_related, Transcription factor: NF-YC aerobic respiration I (cytochrome c) Transcription_related, Transcription factor: GRAS | details |
| TissueCFM000467 | Transcription_related, Transcription factor: NF-YC Phenylpropanoid biosynthesis | details |
| TissueCFM000661 | Plant-pathogen interaction response to symbiont nodulation regulation of nitrogen utilization regulation of phosphorylation regulation of fatty acid biosynthetic process | details |
| TissueCFM000733 | Transcription_related, Transcription factor: BBR-BPC L-valine degradation I non-hydrolytic cleavage of glycosidic bonds, Polysaccharide Lyases: PL4 D-gluconate catabolic process Carbon metabolism gluconokinase activity receptor activity aldehyde dehydrogenase (NAD) activity malonate-semialdehyde dehydrogenase (acetylating) activity protein phosphatase inhibitor activity pectate lyase activity abscisic acid binding methylmalonate-semialdehyde dehydrogenase (acylating) activity regulation of protein serine/threonine phosphatase activity | details |
| TissueCFM000749 | alanyl-tRNA aminoacylation Ser-tRNA(Ala) hydrolase activity alanine-tRNA ligase activity regulation of translational fidelity Transcription_related, Transcription factor: NF-YC tRNA binding vesicle fusion exocytosis Ubiquitin_Proteasome_system, E2: UBC SNARE interactions in vesicular transport Transcription_related, Transcription factor: NAC Ubiquitin mediated proteolysis SNAP receptor activity SNARE binding vesicle-mediated transport protein heterodimerization activity SNARE complex | details |
| TissueCFM000750 | clathrin-mediated endocytosis clathrin heavy chain binding Transcription_related, Transcription factor: BBR-BPC leucopelargonidin and leucocyanidin biosynthesis phosphatidate metabolism, as a signaling molecule structural molecule activity clathrin vesicle coat Transcription_related, Transcription factor: GRAS | details |
| TissueCFM000801 | RNA transport Autophagy - animal MAPK signaling pathway autophagosome assembly DNA topological change Transcription_related, Transcription factor: NF-YC Transcription_related, Transcription factor: Trihelix pre-autophagosomal structure | details |
| TissueCFM000836 | alanyl-tRNA aminoacylation regulation of protein kinase activity regulation of translational fidelity Transcription_related, Transcription factor: NF-YC Ser-tRNA(Ala) hydrolase activity ajmaline and sarpagine biosynthesis alanine-tRNA ligase activity triacylglycerol degradation protein kinase regulator activity tRNA binding RNA transport | details |
| TissueCFM000937 | cytoplasmic ubiquitin ligase complex trans, trans-farnesyl diphosphate biosynthesis geranylgeranyl diphosphate biosynthesis polyisoprenoid biosynthesis superpathway of geranylgeranyl diphosphate biosynthesis II (via MEP) superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate) Atg8 ligase activity Z-farnesyl diphosphate synthase activity actin filament-based process mitophagy farnesyl diphosphate biosynthetic process nucleophagy autophagosome assembly geranyltranstransferase activity non-hydrolytic cleavage of glycosidic bonds, Polysaccharide Lyases: PL4 Transcription_related, Transcription factor: C2C2-GATA dimethylallyltranstransferase activity pectate lyase activity structural constituent of cytoskeleton Autophagy - animal Terpenoid backbone biosynthesis pectin catabolic process protein transport Pentose and glucuronate interconversions | details |
| TissueCFM000957 | adhesion to carbohydrates, Carbohydrate-Binding Modules: CBM57 hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc Transcription_related, Transcription factor: NF-YC formation of glycosidic bonds, GlycosylTransferases: GTnc Transcription_related, Transcription factor: WRKY chitinase activity chitin binding cell wall macromolecule catabolic process Amino sugar and nucleotide sugar metabolism Phenylpropanoid biosynthesis chitin catabolic process transition metal ion binding | details |
| TissueCFM000958 | Phenylpropanoid biosynthesis Transcription_related, Transcription factor: NF-YC formation of glycosidic bonds, GlycosylTransferases: GTnc single-organism biosynthetic process organic substance biosynthetic process gibberellin biosynthesis I (non C-3, non C-13 hydroxylation) gibberellin biosynthesis III (early C-13 hydroxylation) superpathway of scopolin and esculin biosynthesis phenylpropanoids methylation (ice plant) suberin monomers biosynthesis aromatic compound biosynthetic process D-arabinono-1,4-lactone oxidase activity | details |
| TissueCFM000980 | Transcription_related, Transcription factor: NF-YC Transcription_related, Transcription factor: Trihelix peptidyl-proline hydroxylation to 4-hydroxy-L-proline Arginine and proline metabolism MAPK signaling pathway SNARE interactions in vesicular transport procollagen-proline 4-dioxygenase activity L-ascorbic acid binding | details |
| TissueCFM001094 | 6-hydroxymethyl-dihydropterin diphosphate biosynthesis I GDP-glucose biosynthesis oxidized GTP and dGTP detoxification GDP-mannose biosynthesis L-ascorbate biosynthesis I (L-galactose pathway) tetrahydrofolate biosynthesis II RIG-I-like receptor signaling pathway MAPK signaling pathway - yeast mannose-1-phosphate guanylyltransferase (GDP) activity homogalacturonan degradation Fructose and mannose metabolism RNA secondary structure unwinding pectin catabolic process microtubule-based movement cell wall modification biosynthetic process mRNA processing negative regulation of catalytic activity hydrolysis of carbohydrate esters, Carbohydrate Esterases: CE8 | details |
| TissueCFM001139 | microtubule-based movement microtubule binding ATP-dependent microtubule motor activity, plus-end-directed kinesin complex Linoleic acid metabolism phosphoprotein binding (R)-2-hydroxyglutarate dehydrogenase activity 2-hydroxyglutarate dehydrogenase activity cortical microtubule ATP binding cellulose microfibril organization photorespiration jasmonic acid biosynthesis traumatin and (Z)-3-hexen-1-yl acetate biosynthesis Protein_kinases_phosphatases, PPC:4.5.2: CDC2 Like Kinase Family Ubiquitin_Proteasome_system, E2: UBC nitrogen compound metabolic process microtubule microtubule motor activity | details |
| TissueCFM001151 | transcription export complex 2 SAGA complex DUBm complex vesicle organization endosome to lysosome transport positive regulation of proteasomal protein catabolic process transcription elongation from RNA polymerase II promoter Golgi to vacuole transport mRNA export from nucleus positive regulation of RNA polymerase II transcriptional preinitiation complex assembly histone deubiquitination positive gravitropism auxin homeostasis nuclear proteasome complex multivesicular body late endosome membrane retromer complex cytosolic proteasome complex Transcription_related, Transcription factor: NF-YC proteasome regulatory particle, base subcomplex ER-associated ubiquitin-dependent protein catabolic process protein targeting to vacuole Endocytosis Ubiquitin_Proteasome_system, E2: UBC extrinsic component of membrane nuclear pore proteasome-activating ATPase activity transcription coactivator activity TBP-class protein binding phosphatidylinositol binding root development positive regulation of transcription, DNA-templated Proteasome Ubiquitin mediated proteolysis protein transport | details |
| TissueCFM001152 | Transcription_related, Transcription factor: NF-YC transferase activity, transferring phosphorus-containing groups Golgi to vacuole transport endosome to lysosome transport auxin homeostasis vesicle organization positive gravitropism Transcription_related, Transcription factor: Orphans retromer complex multivesicular body late endosome membrane Endocytosis protein targeting to vacuole phosphatidylinositol binding extrinsic component of membrane root development protein binding protein heterodimerization activity | details |
| TissueCFM001182 | Transcription_related, Transcription factor: NF-YC Transcription_related, Transcription factor: Trihelix Ubiquitin_Proteasome_system, E2: UBC SNARE interactions in vesicular transport Ubiquitin mediated proteolysis nucleus | details |
| TissueCFM001327 | Cytochrome_P450, Cytochrome P450: CYP734A Protein_kinases_phosphatases, PPC:1.9.1: CRPK1 Like Kinase (Types 1 and 2) Transcription_related, Transcription factor: NF-YC protein peptidyl-prolyl isomerization phosphorelay signal transduction system chaperone-mediated protein folding brassinosteroids inactivation secologanin and strictosidine biosynthesis Transcription_related, Transcription factor: Orphans NF-kappa B signaling pathway FK506 binding peptidyl-prolyl cis-trans isomerase activity Plant hormone signal transduction protein heterodimerization activity | details |
| TissueCFM001354 | Transcription_related, Transcription factor: BBR-BPC Transcription_related, Transcription regulator: SWI/SNF-BAF60b replication fork Rad51B-Rad51C-Rad51D-XRCC2 complex strand invasion regulation of cyclin-dependent protein serine/threonine kinase activity mitotic recombination regulation of mitotic cell cycle reciprocal meiotic recombination response to ionizing radiation meiotic DNA recombinase assembly Homologous recombination cellular water homeostasis water transport glycerol transport recombinase activity endodeoxyribonuclease activity four-way junction DNA binding water channel activity DNA-dependent ATPase activity glycerol channel activity single-stranded DNA binding double-stranded DNA binding ion transmembrane transport translational initiation translation initiation factor activity | details |
| TissueCFM001356 | alpha-1,2-mannosyltransferase activity protein N-glycosylation (eukaryotic, high mannose) formation of glycosidic bonds, GlycosylTransferases: GTnc Transcription_related, Transcription factor: BBR-BPC Glycosaminoglycan degradation mannosylation N-Glycan biosynthesis ER-associated ubiquitin-dependent protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process Transcription_related, Transcription factor: HB lipid binding | details |
| TissueCFM001380 | Transcription_related, Transcription factor: BBR-BPC response to oxidative stress glutathione-peroxide redox reactions reactive oxygen species degradation L-valine degradation I methylmalonate-semialdehyde dehydrogenase (acylating) activity glutathione peroxidase activity malonate-semialdehyde dehydrogenase (acetylating) activity regulation of mitotic cell cycle Arachidonic acid metabolism regulation of cyclin-dependent protein serine/threonine kinase activity aldehyde dehydrogenase (NAD) activity Transcription_related, Transcription factor: HB Glutathione metabolism glutathione transferase activity lipid binding | details |
| TissueCFM001424 | Ubiquitin mediated proteolysis Transcription_related, Transcription factor: NF-YC Ubiquitin_Proteasome_system, E2: UBC | details |
| TissueCFM001494 | p53 signaling pathway Transcription_related, Transcription factor: NF-YC protein heterodimerization activity | details |
| TissueCFM001499 | leucopelargonidin and leucocyanidin biosynthesis phosphoprotein binding Transcription_related, Transcription factor: HB lipid binding dioxygenase activity | details |
| TissueCFM001576 | pyruvate decarboxylation to acetyl CoA tyrosine catabolic process homogentisate catabolic process actin filament-based process homogentisate 1,2-dioxygenase activity Atg8 ligase activity nucleophagy L-phenylalanine catabolic process mitophagy cytoplasmic ubiquitin ligase complex autophagosome assembly Autophagy - animal Tyrosine metabolism Transcription_related, Transcription factor: C2C2-GATA cytosolic ribosome structural constituent of cytoskeleton | details |
| TissueCFM001639 | L-cysteine biosynthesis I formation of glycosidic bonds, GlycosylTransferases: GTnc hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc plant-type cell wall organization cellular amino acid biosynthetic process cysteine biosynthetic process from serine cell wall cysteine synthase activity beta-galactosidase activity | details |
| TissueCFM001640 | Antigen processing and presentation cell wall hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc cytoplasmic, membrane-bounded vesicle plant-type cell wall organization protein catabolic process beta-galactosidase activity aspartic-type endopeptidase activity dioxygenase activity carbohydrate binding | details |
| TissueCFM001657 | leucopelargonidin and leucocyanidin biosynthesis phosphoprotein binding Protein_kinases_phosphatases, PPC:4.2.6: IRE/NPH/PI dependent/S6 Kinase Transcription_related, Transcription factor: HB water transport glycerol transport cellular water homeostasis glycerol channel activity water channel activity ion transmembrane transport lipid binding | details |
| TissueCFM001665 | phosphoprotein binding Phenylpropanoid biosynthesis Transcription_related, Transcription factor: C2C2-GATA Transcription_related, Transcription factor: HB | details |
| TissueCFM001726 | Glycosaminoglycan degradation 2-hydroxyglutarate dehydrogenase activity (R)-2-hydroxyglutarate dehydrogenase activity phosphoprotein binding Protein_kinases_phosphatases, PPC:4.2.6: IRE/NPH/PI dependent/S6 Kinase Ubiquitin_Proteasome_system, E2: UBC Transcription_related, Transcription factor: HB nitrogen compound metabolic process photorespiration lipid binding | details |
| TissueCFM001767 | Peroxisome regulation of protein kinase activity adhesion to carbohydrates, Carbohydrate-Binding Modules: CBM57 formation of glycosidic bonds, GlycosylTransferases: GTnc hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc Transcription_related, Transcription factor: NF-YC protein kinase regulator activity protein glycosylation galactosyltransferase activity protein heterodimerization activity polysaccharide binding | details |
| TissueCFM001820 | pyruvate decarboxylation to acetyl CoA Carbon metabolism transferase activity, transferring acyl groups formate dehydrogenase (NAD+) activity Atg8 ligase activity homogentisate 1,2-dioxygenase activity phosphoglycerate dehydrogenase activity tyrosine catabolic process homogentisate catabolic process serine family amino acid biosynthetic process formate catabolic process Tyrosine metabolism L-phenylalanine catabolic process nucleophagy mitophagy cytoplasmic ubiquitin ligase complex Autophagy - animal autophagosome assembly cytosolic ribosome cytosol chloroplast part protein transport NAD binding dioxygenase activity | details |
| TissueCFM001836 | Cytochrome_P450, Cytochrome P450: CYP89A serine family amino acid biosynthetic process formate catabolic process vernolate biosynthesis I poly-hydroxy fatty acids biosynthesis Transcription_related, Transcription factor: NF-YC Glycosaminoglycan degradation formate dehydrogenase (NAD+) activity phosphoglycerate dehydrogenase activity | details |
Expression profiles
 Show details about module gene expression profiling |