TreatCFM000122's detailed annotation
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Protein: Yellow color--query protein Green color--interaction proteins. Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
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Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontolog |
|---|---|---|
| 3-hydroxyisobutyryl-CoA hydrolase activity | 0.003722304 | GO:0003860 |
| L-valine degradation I | 0.004425424 | plantCyc |
| histone acetyltransferase activity | 0.004516602 | GO:0004402 |
| heterotrimeric G-protein complex | 0.004875166 | GO:0005834 |
| Cul4-RING E3 ubiquitin ligase complex | 0.005360306 | GO:0080008 |
| organ morphogenesis | 0.006600137 | GO:0009887 |
| regulation of root development | 0.006600137 | GO:2000280 |
| lateral root development | 0.006600137 | GO:0048527 |
| fruit development | 0.006600137 | GO:0010154 |
| defense response to fungus, incompatible interaction | 0.006600137 | GO:0009817 |
| response to extracellular stimulus | 0.006600137 | GO:0009991 |
| endoplasmic reticulum unfolded protein response | 0.006600137 | GO:0030968 |
| reactive oxygen species metabolic process | 0.006600137 | GO:0072593 |
| negative regulation of abscisic acid-activated signaling pathway | 0.010262329 | GO:0009788 |
| Ras signaling pathway | 0.012215977 | KEGG pathway |
| histone acetylation | 0.012530072 | GO:0016573 |
| jasmonic acid mediated signaling pathway | 0.015579589 | GO:0009867 |
| Transcription_related, Transcription regulator: mTERF | 0.015925644 | TF family |
| response to ethylene | 0.017021403 | GO:0009723 |
Module member annotation
| Gene ID | Ortholog in Arabidopsis (Blast E-value) | Annotation in Arabidopsis |
|---|---|---|
| CRO_T000902 | AT2G31670 (2.00E-66) | UP3|UP3 |
| CRO_T008594 | - | - |
| CRO_T008990 | AT4G02715 (2.00E-26) | unknown protein |
| CRO_T009098 | AT2G36000 (2.00E-21) | EMB3114|EMBRYO DEFECTIVE 3114 |
| CRO_T019401 | AT4G31810 (4.00E-133) | ATP-dependent caseinolytic (Clp) protease/crotonase family protein |
| CRO_T020964 | AT2G44420 (1.00E-88) | protein N-terminal asparagine amidohydrolase family protein |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TreatCFM000017 | Oxidative phosphorylation mitochondrion NADH dehydrogenase (ubiquinone) activity mitochondrial inner membrane heme transporter activity heme transport cytochrome-c oxidase activity respiratory chain cytochrome complex assembly hydrogen ion transmembrane transport ATP synthesis coupled electron transport heme binding aerobic respiration hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances aerobic electron transport chain electron transport chain generation of precursor metabolites and energy ATP synthesis coupled proton transport mitochondrial electron transport, NADH to ubiquinone hydrogen ion transmembrane transporter activity quinone binding photosynthetic electron transport in photosystem II succinate dehydrogenase activity electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity succinate dehydrogenase complex | details |
| TreatCFM000032 | details | |
| TreatCFM000065 | Cytochrome_P450, Cytochrome P450: CYP724A | details |
| TreatCFM000076 | Protein_kinases_phosphatases, PPC:4.1.4: MAP2K Ubiquitin_Proteasome_system, DUB: JAMM defense response, incompatible interaction histone modification activation of MAPK activity transcription elongation from RNA polymerase II promoter cullin deneddylation COP9 signalosome Cdc73/Paf1 complex MAP kinase kinase activity MAP kinase activity transcription coactivator activity transcription from RNA polymerase II promoter MAPK cascade MAPK signaling pathway - plant | details |
| TreatCFM000155 | dTTP biosynthetic process dTDP biosynthetic process dUDP biosynthetic process positive regulation of autophagy response to extracellular stimulus thymidylate kinase activity organ morphogenesis pyrimidine deoxyribonucleotide phosphorylation pyrimidine deoxyribonucleotides de novo biosynthesis II superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli) pyrimidine deoxyribonucleotides de novo biosynthesis I regulation of root development lateral root development reactive oxygen species metabolic process endoplasmic reticulum unfolded protein response fruit development RNA biosynthetic process defense response to fungus, incompatible interaction uridylate kinase activity endoplasmic reticulum heterotrimeric G-protein complex negative regulation of abscisic acid-activated signaling pathway Cul4-RING E3 ubiquitin ligase complex Transcription_related, Transcription factor: AP2 Transcription_related, Transcription regulator: mTERF histone acetyltransferase activity histone acetylation Pyrimidine metabolism Ras signaling pathway jasmonic acid mediated signaling pathway response to ethylene phosphoprotein phosphatase activity DNA-directed RNA polymerase activity | details |
| TreatCFM000178 | cell tip growth mitotic spindle assembly checkpoint | details |
| TreatCFM000209 | intracellular Ubiquitin_Proteasome_system, DUB: OTU | details |
| TreatCFM000245 | details | |
| TreatCFM000264 | Protein_kinases_phosphatases, PPC:4.1.4: MAP2K defense response, incompatible interaction activation of MAPK activity MAP kinase kinase activity MAP kinase activity MAPK cascade MAPK signaling pathway - plant | details |
| TreatCFM000280 | defense response, incompatible interaction activation of MAPK activity lipid transporter activity MAP kinase kinase activity MAP kinase activity Protein_kinases_phosphatases, PPC:4.1.4: MAP2K lipid transport MAPK cascade Lysosome adhesion to carbohydrates, Carbohydrate-Binding Modules: CBM57 Protein_kinases_phosphatases, PPC:1.2.2: Receptor Like Cytoplasmic Kinase VII MAPK signaling pathway - plant | details |
| TreatCFM000307 | details | |
| TreatCFM000317 | cytoplasmic, membrane-bounded vesicle | details |
| TreatCFM000331 | Protein_kinases_phosphatases, PPC:4.1.4: MAP2K defense response, incompatible interaction activation of MAPK activity MAP kinase kinase activity MAP kinase activity MAPK cascade MAPK signaling pathway - plant | details |
| TreatCFM000332 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds nitrogen compound metabolic process transferase activity, transferring acyl groups plastid | details |
| TreatCFM000351 | lipid transporter activity lipid transport Lysosome | details |
| TreatCFM000385 | xyloglucan biosynthetic process endomembrane system organization fucose biosynthetic process | details |
| TreatCFM000434 | ADP dimethylallyltransferase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds ATP dimethylallyltransferase activity | details |
| TreatCFM000518 | alkaloid biosynthetic process nitrogen compound metabolic process ajmaline and sarpagine biosynthesis vomilenine glucosyltransferase activity strictosidine beta-glucosidase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds raucaffricine beta-glucosidase activity phospholipid binding | details |
| TreatCFM000613 | Ubiquitin_Proteasome_system, DUB: JAMM proteasome complex precatalytic spliceosome COP9 signalosome cullin deneddylation proteasome-mediated ubiquitin-dependent protein catabolic process response to salt stress Proteasome | details |
| TreatCFM000619 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds nitrogen compound metabolic process transferase activity, transferring acyl groups plastid | details |
| TreatCFM000675 | adhesion to carbohydrates, Carbohydrate-Binding Modules: CBM57 hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc Protein_kinases_phosphatases, PPC:4.1.4: MAP2K endomembrane system organization fucose biosynthetic process xyloglucan biosynthetic process defense response, incompatible interaction activation of MAPK activity MAP kinase kinase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds cell wall macromolecule catabolic process | details |
| TreatCFM000725 | Protein_kinases_phosphatases, PPC:4.1.4: MAP2K defense response, incompatible interaction activation of MAPK activity MAP kinase kinase activity MAP kinase activity MAPK cascade MAPK signaling pathway - plant | details |
| TreatCFM000750 | Protein_kinases_phosphatases, PPC:4.1.4: MAP2K activation of MAPK activity defense response, incompatible interaction MAP kinase kinase activity MAP kinase activity MAPK cascade MAPK signaling pathway - plant | details |
| TreatCFM000764 | Protein_kinases_phosphatases, PPC:4.1.4: MAP2K activation of MAPK activity defense response, incompatible interaction MAP kinase kinase activity | details |
| TreatCFM000765 | cytoplasmic, membrane-bounded vesicle | details |
| TreatCFM000774 | COP9 signalosome cullin deneddylation Ubiquitin_Proteasome_system, DUB: JAMM | details |
| TreatCFM000786 | details | |
| TreatCFM000794 | Protein_kinases_phosphatases, PPC:4.1.4: MAP2K defense response, incompatible interaction activation of MAPK activity MAP kinase kinase activity MAP kinase activity MAPK cascade MAPK signaling pathway - plant | details |
| TreatCFM000829 | Ubiquitin_Proteasome_system, DUB: JAMM cullin deneddylation COP9 signalosome carbohydrate transport | details |
| TreatCFM000835 | details | |
| TreatCFM000969 | cytoplasmic, membrane-bounded vesicle | details |
| TreatCFM001014 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds nitrogen compound metabolic process transferase activity, transferring acyl groups plastid | details |
| TreatCFM001037 | vacuole | details |
| TreatCFM001076 | mitotic spindle assembly checkpoint ATP synthesis coupled electron transport Transcription_related, Transcription factor: bZIP NADH dehydrogenase (ubiquinone) activity mitochondrion | details |
| TreatCFM001155 | regulation of root development response to extracellular stimulus lateral root development organ morphogenesis fruit development defense response to fungus, incompatible interaction reactive oxygen species metabolic process endoplasmic reticulum unfolded protein response heterotrimeric G-protein complex Cul4-RING E3 ubiquitin ligase complex negative regulation of abscisic acid-activated signaling pathway histone acetylation histone acetyltransferase activity glucan endo-1,3-beta-D-glucosidase activity oxidized purine nucleobase lesion DNA N-glycosylase activity Ras signaling pathway jasmonic acid mediated signaling pathway damaged DNA binding response to ethylene adhesion to carbohydrates, Carbohydrate-Binding Modules: CBM57 hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc Transcription_related, Transcription regulator: mTERF cytosolic small ribosomal subunit DNA repair small GTPase mediated signal transduction | details |
| TreatCFM001222 | intracellular protein transport | details |
| TreatCFM001234 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds nitrogen compound metabolic process transferase activity, transferring acyl groups plastid | details |
| TreatCFM001265 | details | |
| TreatCFM001331 | 3-deoxy-8-phosphooctulonate synthase activity thymidylate kinase activity response to extracellular stimulus dUDP biosynthetic process dTTP biosynthetic process dTDP biosynthetic process organ morphogenesis regulation of root development reactive oxygen species metabolic process lateral root development CMP-3-deoxy-D-manno-octulosonate biosynthesis pyrimidine deoxyribonucleotide phosphorylation pyrimidine deoxyribonucleotides de novo biosynthesis II superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli) fruit development endoplasmic reticulum unfolded protein response uridylate kinase activity defense response to fungus, incompatible interaction pyrimidine deoxyribonucleotides de novo biosynthesis I endoplasmic reticulum heterotrimeric G-protein complex negative regulation of abscisic acid-activated signaling pathway histone acetyltransferase activity Cul4-RING E3 ubiquitin ligase complex histone acetylation Transcription_related, Transcription regulator: mTERF Lipopolysaccharide biosynthesis jasmonic acid mediated signaling pathway response to ethylene Ras signaling pathway Pyrimidine metabolism biosynthetic process helicase activity RNA degradation | details |
| TreatCFM001493 | activation of MAPK activity defense response, incompatible interaction fucose biosynthetic process xyloglucan biosynthetic process endomembrane system organization Ribosome MAP kinase kinase activity lipid transporter activity Protein_kinases_phosphatases, PPC:4.1.4: MAP2K structural constituent of ribosome 5S rRNA binding MAP kinase activity translation lipid transport salicylic acid mediated signaling pathway unidimensional cell growth adhesion to carbohydrates, Carbohydrate-Binding Modules: CBM57 formation of glycosidic bonds, GlycosylTransferases: GTnc Protein_kinases_phosphatases, PPC:1.2.2: Receptor Like Cytoplasmic Kinase VII integral component of Golgi membrane MAPK cascade aerobic respiration I (cytochrome c) aerobic respiration III (alternative oxidase pathway) detoxification of reactive carbonyls in chloroplasts Flavonoid biosynthesis flavonoid biosynthesis (in equisetum) leucodelphinidin biosynthesis NAD/NADH phosphorylation and dephosphorylation pinobanksin biosynthesis xyloglucan biosynthesis Lysosome single-organism metabolic process | details |
| TreatCFM001637 | Ubiquitin_Proteasome_system, DUB: JAMM rosmarinic acid biosynthesis I rosmarinic acid biosynthesis II 4-hydroxybenzoate biosynthesis I (eukaryotes) rRNA primary transcript binding oligosaccharyltransferase complex COP9 signalosome maturation of LSU-rRNA maturation of 5.8S rRNA protein N-linked glycosylation cullin deneddylation oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor ribosomal large subunit assembly NAD binding preribosome, large subunit precursor N-Glycan biosynthesis embryo development ending in seed dormancy | details |
| TreatCFM001930 | response to extracellular stimulus lateral root development reactive oxygen species metabolic process organ morphogenesis endoplasmic reticulum unfolded protein response regulation of root development fruit development defense response to fungus, incompatible interaction leucopelargonidin and leucocyanidin biosynthesis negative regulation of abscisic acid-activated signaling pathway Ras signaling pathway histone acetylation Transcription_related, Transcription regulator: mTERF heterotrimeric G-protein complex jasmonic acid mediated signaling pathway Cul4-RING E3 ubiquitin ligase complex Phenylpropanoid biosynthesis response to ethylene RNA degradation exocytosis exocyst | details |
| TreatCFM002101 | CMP-3-deoxy-D-manno-octulosonate biosynthesis RNA degradation Lipopolysaccharide biosynthesis fruit development organ morphogenesis reactive oxygen species metabolic process endoplasmic reticulum unfolded protein response lateral root development regulation of root development response to extracellular stimulus defense response to fungus, incompatible interaction 3-deoxy-8-phosphooctulonate synthase activity Autophagy - animal Ras signaling pathway Protein_kinases_phosphatases, PPC:1.1.1: Leucine-rich transmembrane protein kinase/Strubbelig Receptor Family 1 ATG1/ULK1 kinase complex heterotrimeric G-protein complex negative regulation of abscisic acid-activated signaling pathway autophagy histone acetylation ATP binding large ribosomal subunit rRNA binding Cul4-RING E3 ubiquitin ligase complex histone acetyltransferase activity Transcription_related, Transcription regulator: mTERF jasmonic acid mediated signaling pathway response to ethylene poly(A) RNA binding biosynthetic process RNA processing | details |
| TreatCFM002139 | geranylgeraniol kinase activity geraniol kinase activity CTP:2-trans,-6-trans-farnesol kinase activity soluble NSF attachment protein activity farnesylcysteine salvage pathway SNARE complex disassembly farnesol metabolic process protein import syntaxin binding protein targeting membrane fusion carpel development adenosine ribonucleotides de novo biosynthesis Transcription_related, Transcription factor: FAR1 ABC transporters Autophagy - yeast Protein export Terpenoid backbone biosynthesis ATP binding nucleotidyltransferase activity amino acid binding | details |
| TreatCFM002144 | glutaminyl-tRNAgln biosynthesis via transamidation ATG1/ULK1 kinase complex heterotrimeric G-protein complex glutamyl-tRNA(Gln) amidotransferase complex lateral root development glutaminyl-tRNAGln biosynthesis via transamidation response to extracellular stimulus regulation of root development organ morphogenesis reactive oxygen species metabolic process glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity endoplasmic reticulum unfolded protein response fruit development defense response to fungus, incompatible interaction mitochondrial translation negative regulation of abscisic acid-activated signaling pathway Cul4-RING E3 ubiquitin ligase complex autophagy histone acetylation Transcription_related, Transcription regulator: mTERF Autophagy - animal Ras signaling pathway histone acetyltransferase activity jasmonic acid mediated signaling pathway response to ethylene exocyst exocytosis Aminoacyl-tRNA biosynthesis RNA degradation helicase activity | details |
Expression profiles
 Show details about module gene expression profiling |