TreatCFM001637's detailed annotation
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Protein: Yellow color--query protein Green color--interaction proteins. Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
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Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontolog |
|---|---|---|
| Ubiquitin_Proteasome_system, DUB: JAMM | 0.002480253 | ubs family |
| rosmarinic acid biosynthesis I | 0.002924883 | plantCyc |
| rosmarinic acid biosynthesis II | 0.002924883 | plantCyc |
| 4-hydroxybenzoate biosynthesis I (eukaryotes) | 0.005520291 | plantCyc |
| rRNA primary transcript binding | 0.005849767 | GO:0042134 |
| oligosaccharyltransferase complex | 0.010421681 | GO:0008250 |
| COP9 signalosome | 0.010421681 | GO:0008180 |
| maturation of LSU-rRNA | 0.011254147 | GO:0000470 |
| maturation of 5.8S rRNA | 0.011254147 | GO:0000460 |
| protein N-linked glycosylation | 0.011254147 | GO:0006487 |
| cullin deneddylation | 0.011254147 | GO:0010388 |
| oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | 0.012169917 | GO:0016616 |
| ribosomal large subunit assembly | 0.017346871 | GO:0000027 |
| NAD binding | 0.021354275 | GO:0051287 |
| preribosome, large subunit precursor | 0.02168458 | GO:0030687 |
| N-Glycan biosynthesis | 0.027559619 | KEGG pathway |
| embryo development ending in seed dormancy | 0.044784394 | GO:0009793 |
Module member annotation
| Gene ID | Ortholog in Arabidopsis (Blast E-value) | Annotation in Arabidopsis |
|---|---|---|
| CRO_T012733 | AT4G26430 (7.00E-134) | CSN6B|COP9 signalosome subunit 6B |
| CRO_T017295 | AT1G44770 (4.00E-47) | unknown protein |
| CRO_T020964 | AT2G44420 (1.00E-88) | protein N-terminal asparagine amidohydrolase family protein |
| CRO_T021332 | AT1G12550 (2.00E-20) | HPR3|hydroxypyruvate reductase 3 |
| CRO_T027408 | AT4G21150 (1.00E-174) | HAP6|HAPLESS 6; RPN2|RIBOPHORIN II |
| CRO_T028895 | AT4G01560 (6.00E-129) | MEE49|maternal effect embryo arrest 49 |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TreatCFM000017 | Oxidative phosphorylation mitochondrion NADH dehydrogenase (ubiquinone) activity mitochondrial inner membrane heme transporter activity heme transport cytochrome-c oxidase activity respiratory chain cytochrome complex assembly hydrogen ion transmembrane transport ATP synthesis coupled electron transport heme binding aerobic respiration hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances aerobic electron transport chain electron transport chain generation of precursor metabolites and energy ATP synthesis coupled proton transport mitochondrial electron transport, NADH to ubiquinone hydrogen ion transmembrane transporter activity quinone binding photosynthetic electron transport in photosystem II succinate dehydrogenase activity electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity succinate dehydrogenase complex | details |
| TreatCFM000032 | details | |
| TreatCFM000065 | Cytochrome_P450, Cytochrome P450: CYP724A | details |
| TreatCFM000073 | cullin deneddylation COP9 signalosome Ubiquitin_Proteasome_system, DUB: JAMM Oxidative phosphorylation | details |
| TreatCFM000076 | Protein_kinases_phosphatases, PPC:4.1.4: MAP2K Ubiquitin_Proteasome_system, DUB: JAMM defense response, incompatible interaction histone modification activation of MAPK activity transcription elongation from RNA polymerase II promoter cullin deneddylation COP9 signalosome Cdc73/Paf1 complex MAP kinase kinase activity MAP kinase activity transcription coactivator activity transcription from RNA polymerase II promoter MAPK cascade MAPK signaling pathway - plant | details |
| TreatCFM000118 | Ubiquitin_Proteasome_system, DUB: JAMM formation of glycosidic bonds, GlycosylTransferases: GTnc | details |
| TreatCFM000122 | 3-hydroxyisobutyryl-CoA hydrolase activity L-valine degradation I histone acetyltransferase activity heterotrimeric G-protein complex Cul4-RING E3 ubiquitin ligase complex organ morphogenesis regulation of root development lateral root development fruit development defense response to fungus, incompatible interaction response to extracellular stimulus endoplasmic reticulum unfolded protein response reactive oxygen species metabolic process negative regulation of abscisic acid-activated signaling pathway Ras signaling pathway histone acetylation jasmonic acid mediated signaling pathway Transcription_related, Transcription regulator: mTERF response to ethylene | details |
| TreatCFM000178 | cell tip growth mitotic spindle assembly checkpoint | details |
| TreatCFM000182 | trans-zeatin biosynthesis | details |
| TreatCFM000209 | intracellular Ubiquitin_Proteasome_system, DUB: OTU | details |
| TreatCFM000214 | tubulin binding formation of glycosidic bonds, GlycosylTransferases: GTnc lipid IVA biosynthesis Lipopolysaccharide biosynthesis organophosphate metabolic process carbohydrate derivative metabolic process protein N-glycosylation (eukaryotic, high mannose) tubulin complex assembly cullin deneddylation | details |
| TreatCFM000233 | Ubiquitin_Proteasome_system, DUB: JAMM cullin deneddylation COP9 signalosome carbohydrate transport | details |
| TreatCFM000245 | details | |
| TreatCFM000264 | Protein_kinases_phosphatases, PPC:4.1.4: MAP2K defense response, incompatible interaction activation of MAPK activity MAP kinase kinase activity MAP kinase activity MAPK cascade MAPK signaling pathway - plant | details |
| TreatCFM000269 | intracellular COP9 signalosome Ubiquitin_Proteasome_system, DUB: JAMM cullin deneddylation GTP binding small GTPase mediated signal transduction intracellular protein transport | details |
| TreatCFM000280 | defense response, incompatible interaction activation of MAPK activity lipid transporter activity MAP kinase kinase activity MAP kinase activity Protein_kinases_phosphatases, PPC:4.1.4: MAP2K lipid transport MAPK cascade Lysosome adhesion to carbohydrates, Carbohydrate-Binding Modules: CBM57 Protein_kinases_phosphatases, PPC:1.2.2: Receptor Like Cytoplasmic Kinase VII MAPK signaling pathway - plant | details |
| TreatCFM000307 | details | |
| TreatCFM000317 | cytoplasmic, membrane-bounded vesicle | details |
| TreatCFM000331 | Protein_kinases_phosphatases, PPC:4.1.4: MAP2K defense response, incompatible interaction activation of MAPK activity MAP kinase kinase activity MAP kinase activity MAPK cascade MAPK signaling pathway - plant | details |
| TreatCFM000332 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds nitrogen compound metabolic process transferase activity, transferring acyl groups plastid | details |
| TreatCFM000349 | benzoyl-CoA biosynthesis formation of glycosidic bonds, GlycosylTransferases: GTnc Transcription_related, Transcription factor: BES1 Transcription_related, Transcription regulator: LIM Ubiquitin_Proteasome_system, DUB: JAMM glycoprotein 2-beta-D-xylosyltransferase activity fatty acid β-oxidation II (peroxisome) transcription factor activity, sequence-specific DNA binding transcription regulatory region DNA binding benzoate biosynthesis I (CoA-dependent, β-oxidative) protein N-linked glycosylation formation of translation preinitiation complex regulation of transcription, DNA-templated carbohydrate transport regulation of translational initiation brassinosteroid mediated signaling pathway | details |
| TreatCFM000351 | lipid transporter activity lipid transport Lysosome | details |
| TreatCFM000368 | COP9 signalosome cullin deneddylation Ubiquitin_Proteasome_system, DUB: JAMM | details |
| TreatCFM000385 | xyloglucan biosynthetic process endomembrane system organization fucose biosynthetic process | details |
| TreatCFM000434 | ADP dimethylallyltransferase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds ATP dimethylallyltransferase activity | details |
| TreatCFM000442 | cullin deneddylation Ubiquitin_Proteasome_system, DUB: JAMM COP9 signalosome Phenylpropanoid biosynthesis intracellular part ATP-dependent helicase activity coenzyme binding | details |
| TreatCFM000510 | pyrimidine ribonucleosides salvage I cullin deneddylation pyrimidine nucleoside salvage pyrimidine nucleobase metabolic process DNA integration Ubiquitin_Proteasome_system, DUB: JAMM COP9 signalosome uridine kinase activity Transcription_related, Transcription factor: B3 | details |
| TreatCFM000518 | alkaloid biosynthetic process nitrogen compound metabolic process ajmaline and sarpagine biosynthesis vomilenine glucosyltransferase activity strictosidine beta-glucosidase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds raucaffricine beta-glucosidase activity phospholipid binding | details |
| TreatCFM000574 | cullin deneddylation COP9 signalosome Ubiquitin_Proteasome_system, DUB: JAMM Transcription_related, Transcription factor: B3 Transcription_related, Transcription factor: WRKY | details |
| TreatCFM000600 | cullin deneddylation COP9 signalosome Ubiquitin_Proteasome_system, DUB: JAMM | details |
| TreatCFM000601 | cullin deneddylation COP9 signalosome Ubiquitin_Proteasome_system, DUB: JAMM | details |
| TreatCFM000607 | cullin deneddylation COP9 signalosome Ubiquitin_Proteasome_system, DUB: JAMM | details |
| TreatCFM000608 | COP9 signalosome Ubiquitin_Proteasome_system, DUB: JAMM cullin deneddylation DNA integration | details |
| TreatCFM000613 | Ubiquitin_Proteasome_system, DUB: JAMM proteasome complex precatalytic spliceosome COP9 signalosome cullin deneddylation proteasome-mediated ubiquitin-dependent protein catabolic process response to salt stress Proteasome | details |
| TreatCFM000619 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds nitrogen compound metabolic process transferase activity, transferring acyl groups plastid | details |
| TreatCFM000630 | Ubiquitin_Proteasome_system, DUB: JAMM cullin deneddylation COP9 signalosome small GTPase mediated signal transduction GTP binding | details |
| TreatCFM000631 | COP9 signalosome Ubiquitin_Proteasome_system, DUB: JAMM cullin deneddylation DNA integration | details |
| TreatCFM000675 | adhesion to carbohydrates, Carbohydrate-Binding Modules: CBM57 hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc Protein_kinases_phosphatases, PPC:4.1.4: MAP2K endomembrane system organization fucose biosynthetic process xyloglucan biosynthetic process defense response, incompatible interaction activation of MAPK activity MAP kinase kinase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds cell wall macromolecule catabolic process | details |
| TreatCFM000715 | Ubiquitin_Proteasome_system, DUB: JAMM cullin deneddylation COP9 signalosome proteasome complex Proteasome proteasome-mediated ubiquitin-dependent protein catabolic process | details |
| TreatCFM000725 | Protein_kinases_phosphatases, PPC:4.1.4: MAP2K defense response, incompatible interaction activation of MAPK activity MAP kinase kinase activity MAP kinase activity MAPK cascade MAPK signaling pathway - plant | details |
| TreatCFM000750 | Protein_kinases_phosphatases, PPC:4.1.4: MAP2K activation of MAPK activity defense response, incompatible interaction MAP kinase kinase activity MAP kinase activity MAPK cascade MAPK signaling pathway - plant | details |
| TreatCFM000764 | Protein_kinases_phosphatases, PPC:4.1.4: MAP2K activation of MAPK activity defense response, incompatible interaction MAP kinase kinase activity | details |
| TreatCFM000765 | cytoplasmic, membrane-bounded vesicle | details |
| TreatCFM000774 | COP9 signalosome cullin deneddylation Ubiquitin_Proteasome_system, DUB: JAMM | details |
| TreatCFM000786 | details | |
| TreatCFM000794 | Protein_kinases_phosphatases, PPC:4.1.4: MAP2K defense response, incompatible interaction activation of MAPK activity MAP kinase kinase activity MAP kinase activity MAPK cascade MAPK signaling pathway - plant | details |
| TreatCFM000829 | Ubiquitin_Proteasome_system, DUB: JAMM cullin deneddylation COP9 signalosome carbohydrate transport | details |
| TreatCFM000835 | details | |
| TreatCFM000859 | coenzyme A biosynthesis I Ubiquitin_Proteasome_system, DUB: JAMM cullin deneddylation COP9 signalosome small ribosomal subunit | details |
| TreatCFM000869 | fucosyltransferase activity Various types of N-glycan biosynthesis formation of glycosidic bonds, GlycosylTransferases: GTnc Lewis a epitope biosynthetic process fucosylation Ubiquitin_Proteasome_system, DUB: JAMM COP9 signalosome Golgi cisterna membrane cullin deneddylation protein glycosylation | details |
| TreatCFM000870 | COP9 signalosome cullin deneddylation Ubiquitin_Proteasome_system, DUB: JAMM ubiquitin-protein transferase activity Ubiquitin_Proteasome_system, E3: U-box protein ubiquitination | details |
| TreatCFM000876 | cullin deneddylation COP9 signalosome Ubiquitin_Proteasome_system, DUB: JAMM | details |
| TreatCFM000923 | cullin deneddylation COP9 signalosome Ubiquitin_Proteasome_system, DUB: JAMM | details |
| TreatCFM000964 | cullin deneddylation COP9 signalosome Ubiquitin_Proteasome_system, DUB: JAMM Phenylpropanoid biosynthesis coenzyme binding | details |
| TreatCFM000969 | cytoplasmic, membrane-bounded vesicle | details |
| TreatCFM001014 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds nitrogen compound metabolic process transferase activity, transferring acyl groups plastid | details |
| TreatCFM001037 | vacuole | details |
| TreatCFM001067 | cullin deneddylation COP9 signalosome Ubiquitin_Proteasome_system, DUB: JAMM | details |
| TreatCFM001069 | cullin deneddylation COP9 signalosome Ubiquitin_Proteasome_system, DUB: JAMM Transcription_related, Transcription factor: B3 catalytic activity | details |
| TreatCFM001076 | mitotic spindle assembly checkpoint ATP synthesis coupled electron transport Transcription_related, Transcription factor: bZIP NADH dehydrogenase (ubiquinone) activity mitochondrion | details |
| TreatCFM001084 | cullin deneddylation COP9 signalosome Ubiquitin_Proteasome_system, DUB: JAMM | details |
| TreatCFM001102 | cullin deneddylation COP9 signalosome Ubiquitin_Proteasome_system, DUB: JAMM | details |
| TreatCFM001204 | 1,3-β-D-glucan biosynthesis Ubiquitin_Proteasome_system, DUB: JAMM COP9 signalosome spliceosomal complex 1,3-beta-D-glucan synthase complex ubiquitin ligase complex positive regulation of proteasomal ubiquitin-dependent protein catabolic process cullin deneddylation (1->3)-beta-D-glucan biosynthetic process ubiquitin conjugating enzyme binding 1,3-beta-D-glucan synthase activity | details |
| TreatCFM001206 | Ubiquitin_Proteasome_system, DUB: JAMM cullin deneddylation COP9 signalosome nitrogen compound metabolic process hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds Phenylpropanoid biosynthesis plastid coenzyme binding transferase activity, transferring acyl groups | details |
| TreatCFM001221 | Ubiquitin_Proteasome_system, DUB: JAMM cullin deneddylation COP9 signalosome carbohydrate transport | details |
| TreatCFM001222 | intracellular protein transport | details |
| TreatCFM001234 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds nitrogen compound metabolic process transferase activity, transferring acyl groups plastid | details |
| TreatCFM001254 | cullin deneddylation COP9 signalosome Ubiquitin_Proteasome_system, DUB: JAMM | details |
| TreatCFM001265 | details | |
| TreatCFM001329 | cullin deneddylation COP9 signalosome Ubiquitin_Proteasome_system, DUB: JAMM | details |
| TreatCFM001638 | Protein_kinases_phosphatases, PPC:2.2.1: Unknown Function Kinase Cell cycle - Caulobacter Protein_kinases_phosphatases, PPC:4.5.2: CDC2 Like Kinase Family protein kinase activity | details |
| TreatCFM001704 | Ubiquitin_Proteasome_system, DUB: JAMM hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds RNA polymerase II transcription factor activity, sequence-specific DNA binding cullin deneddylation ribosomal large subunit assembly nitrogen compound metabolic process COP9 signalosome nucleoplasm transferase activity, transferring acyl groups | details |
Expression profiles
 Show details about module gene expression profiling |