TreatCFM000131's detailed annotation
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Protein: Yellow color--query protein Green color--interaction proteins. Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
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Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontolog |
|---|---|---|
| post-embryonic root development | 0.004416395 | GO:0048528 |
| U5 snRNA 3'-end processing | 0.004416395 | GO:0034476 |
| exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 0.004416395 | GO:0043928 |
| exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 0.004416395 | GO:0000467 |
| nuclear polyadenylation-dependent mRNA catabolic process | 0.004416395 | GO:0071042 |
| nuclear polyadenylation-dependent tRNA catabolic process | 0.004416395 | GO:0071038 |
| U1 snRNA 3'-end processing | 0.004416395 | GO:0034473 |
| nuclear polyadenylation-dependent rRNA catabolic process | 0.004416395 | GO:0071035 |
| nuclear mRNA surveillance | 0.004579626 | GO:0071028 |
| nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' | 0.004816817 | GO:0034427 |
| U4 snRNA 3'-end processing | 0.004816817 | GO:0034475 |
| MAPK signaling pathway - yeast | 0.007971652 | KEGG pathway |
| AU-rich element binding | 0.010424761 | GO:0017091 |
| protein domain specific binding | 0.016928975 | GO:0019904 |
| cytoplasmic exosome (RNase complex) | 0.016928975 | GO:0000177 |
| nuclear exosome (RNase complex) | 0.016928975 | GO:0000176 |
| RNA degradation | 0.019577886 | KEGG pathway |
| Transcription_related, Transcription factor: HB | 0.039681974 | TF family |
Module member annotation
| Gene ID | Ortholog in Arabidopsis (Blast E-value) | Annotation in Arabidopsis |
|---|---|---|
| CRO_T001705 | AT3G19510 (1.00E-51) | HAT3.1|Homeodomain-like protein with RING/FYVE/PHD-type zinc finger domain |
| CRO_T009790 | AT3G07750 (6.00E-131) | 3'-5'-exoribonuclease family protein |
| CRO_T012749 | AT3G59480 (0.000000001) | pfkB-like carbohydrate kinase family protein |
| CRO_T014904 | AT4G26000 (4.00E-78) | PEP|PEPPER |
| CRO_T023236 | AT1G78220 (3.00E-67) | GF14 PI|GF 14 PI CHAIN; GRF13|general regulatory factor 13 |
| CRO_T025234 | - | - |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TreatCFM000096 | Protein_kinases_phosphatases, PPC:1.4.1: Crinkly 4 Like Kinase DNA ligation involved in DNA repair double-strand break repair via nonhomologous end joining lagging strand elongation protein ADP-ribosylation nucleic acid binding hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances NAD+ ADP-ribosyltransferase activity DNA ligase (ATP) activity adenosine ribonucleotides de novo biosynthesis Base excision repair NF-kappa B signaling pathway | details |
| TreatCFM000208 | adenosine ribonucleotides de novo biosynthesis Golgi apparatus cell division site cell plate plant-type vacuole nuclear envelope cytokinesis by cell plate formation nucleic acid binding O-acetyltransferase activity cell wall organization or biogenesis | details |
| TreatCFM000254 | Amyotrophic lateral sclerosis (ALS) Transcription_related, Transcription regulator: SWI/SNF-SWI3 mitochondrial outer membrane translocase complex spermine and spermidine degradation III histone H3-K4 methylation protein import into mitochondrial matrix protein channel activity | details |
| TreatCFM000615 | hydrolase activity, hydrolyzing N-glycosyl compounds trans-zeatin biosynthesis damaged DNA binding nucleus response to UV-B cytokinin biosynthetic process Cul4-RING E3 ubiquitin ligase complex Ubiquitin mediated proteolysis DNA repair Ubiquitin_Proteasome_system, E3 adaptor: DWD | details |
| TreatCFM000637 | Amyotrophic lateral sclerosis (ALS) mitochondrial outer membrane translocase complex protein import into mitochondrial matrix vacuolar transport NLS-bearing protein import into nucleus base-excision repair DNA N-glycosylase activity nucleoplasm nuclear pore Base excision repair Lysosome regulation of catalytic activity nuclear localization sequence binding protein channel activity cysteine-type endopeptidase activity protein transporter activity Endocytosis | details |
| TreatCFM000830 | MAPK signaling pathway - yeast Transcriptional misregulation in cancers positive regulation of phosphorylation of RNA polymerase II C-terminal domain positive regulation of cyclin-dependent protein serine/threonine kinase activity Golgi vesicle budding post-embryonic root development phospholipid translocation positive regulation of transcription from RNA polymerase II promoter protein domain specific binding phospholipid-translocating ATPase activity cyclin-dependent protein serine/threonine kinase regulator activity cyclin-dependent protein kinase holoenzyme complex | details |
| TreatCFM000831 | post-embryonic root development MAPK signaling pathway - yeast protein domain specific binding | details |
| TreatCFM000988 | regulation of plant-type hypersensitive response cellular response to gravity regulation of ARF protein signal transduction response to cadmium ion ARF guanyl-nucleotide exchange factor activity threonine-type endopeptidase activity structural constituent of cytoskeleton microtubule-based process Phagosome tubulin complex positive regulation of GTPase activity Aminoacyl-tRNA biosynthesis Proteasome proteolysis involved in cellular protein catabolic process vesicle-mediated transport Endocytosis proteasome core complex GTPase activity | details |
| TreatCFM001161 | Transcription_related, Transcription regulator: LIM glycolysis I (from glucose 6-phosphate) Transcription_related, Transcription factor: C2H2 | details |
| TreatCFM001242 | DNA replication, synthesis of RNA primer primosome complex DNA primase activity Cell cycle 4 iron, 4 sulfur cluster binding | details |
| TreatCFM001380 | Fanconi anemia pathway Pyrimidine metabolism pollen exine formation pyrimidine nucleotide biosynthetic process 'de novo' pyrimidine nucleobase biosynthetic process nucleotide phosphorylation CMP phosphorylation pyrimidine deoxyribonucleotide phosphorylation UTP and CTP de novo biosynthesis cytidylate kinase activity uridylate kinase activity adhesion to carbohydrates, Carbohydrate-Binding Modules: CBM57 hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc adenosine ribonucleotides de novo biosynthesis pyrimidine ribonucleotides interconversion | details |
| TreatCFM001381 | vacuolar transport Arachidonic acid metabolism Fanconi anemia pathway Endocytosis | details |
| TreatCFM001410 | polyamine transmembrane transport mitotic spindle assembly checkpoint Transcription_related, Transcription factor: bZIP cellular metabolic process amino acid transmembrane transport L-amino acid transmembrane transporter activity polyamine transmembrane transporter activity Cell cycle | details |
| TreatCFM001612 | post-embryonic root development Ubiquitin_Proteasome_system, E1: ThiF MAPK signaling pathway MAPK signaling pathway - yeast protein neddylation removal of superoxide radicals oxalate metabolic process NEDD8 activating enzyme activity acid-amino acid ligase activity cellular protein metabolic process oxalate decarboxylase activity protein domain specific binding superoxide dismutase activity nutrient reservoir activity manganese ion binding Ubiquitin mediated proteolysis | details |
| TreatCFM001861 | post-embryonic root development ether hydrolase activity Adherens junction xyloglucan biosynthesis PPAR signaling pathway MAPK signaling pathway - yeast protein domain specific binding formation of glycosidic bonds, GlycosylTransferases: GTnc Ubiquitin_Proteasome_system, E2: UBC | details |
| TreatCFM001888 | 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity 3'-phospho-5'-adenylyl sulfate transmembrane transport Transcription_related, Transcription regulator: TRAF integral component of Golgi membrane clathrin vesicle coat integral component of endoplasmic reticulum membrane ATP-dependent peptidase activity Ubiquitin_Proteasome_system, E3 adaptor: BTB carbohydrate transport Plant hormone signal transduction vesicle-mediated transport endomembrane system | details |
| TreatCFM002029 | Transcription_related, Transcription regulator: TRAF Ubiquitin_Proteasome_system, E3 adaptor: BTB Plant hormone signal transduction Spliceosome | details |
Expression profiles
 Show details about module gene expression profiling |