TreatCFM001888's detailed annotation
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Protein: Yellow color--query protein Green color--interaction proteins. Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
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Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontolog |
|---|---|---|
| 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity | 0.004550155 | GO:0046964 |
| 3'-phospho-5'-adenylyl sulfate transmembrane transport | 0.006894174 | GO:1902559 |
| Transcription_related, Transcription regulator: TRAF | 0.009298062 | TF family |
| integral component of Golgi membrane | 0.010129046 | GO:0030173 |
| clathrin vesicle coat | 0.010129046 | GO:0030125 |
| integral component of endoplasmic reticulum membrane | 0.010129046 | GO:0030176 |
| ATP-dependent peptidase activity | 0.014192785 | GO:0004176 |
| Ubiquitin_Proteasome_system, E3 adaptor: BTB | 0.017907868 | ubs family |
| carbohydrate transport | 0.026651053 | GO:0008643 |
| Plant hormone signal transduction | 0.033240934 | KEGG pathway |
| vesicle-mediated transport | 0.041116473 | GO:0016192 |
| endomembrane system | 0.048387261 | GO:0012505 |
Module member annotation
| Gene ID | Ortholog in Arabidopsis (Blast E-value) | Annotation in Arabidopsis |
|---|---|---|
| CRO_T000771 | AT2G25740 (3.00E-158) | ATP-dependent protease La (LON) domain protein |
| CRO_T002856 | AT2G40060 (2.00E-18) | CLC2|clathrin light chain 2 |
| CRO_T002899 | AT1G12340 (2.00E-14) | Cornichon family protein |
| CRO_T003686 | AT1G12600 (3.00E-151) | UDP-N-acetylglucosamine (UAA) transporter family |
| CRO_T005861 | AT1G64280 (9.00E-157) | ATNPR1|ARABIDOPSIS NONEXPRESSER OF PR GENES 1; NIM1|NON-INDUCIBLE IMMUNITY 1; NPR1|NONEXPRESSER OF PR GENES 1; SAI1|SALICYLIC ACID INSENSITIVE 1 |
| CRO_T014904 | AT4G26000 (4.00E-78) | PEP|PEPPER |
| CRO_T016536 | AT5G48830 (8.00E-99) | unknown protein |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TreatCFM000064 | clathrin vesicle coat secologanin and strictosidine biosynthesis Transcription_related, Transcription factor: NAC | details |
| TreatCFM000096 | Protein_kinases_phosphatases, PPC:1.4.1: Crinkly 4 Like Kinase DNA ligation involved in DNA repair double-strand break repair via nonhomologous end joining lagging strand elongation protein ADP-ribosylation nucleic acid binding hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances NAD+ ADP-ribosyltransferase activity DNA ligase (ATP) activity adenosine ribonucleotides de novo biosynthesis Base excision repair NF-kappa B signaling pathway | details |
| TreatCFM000131 | post-embryonic root development U5 snRNA 3'-end processing exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) nuclear polyadenylation-dependent mRNA catabolic process nuclear polyadenylation-dependent tRNA catabolic process U1 snRNA 3'-end processing nuclear polyadenylation-dependent rRNA catabolic process nuclear mRNA surveillance nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' U4 snRNA 3'-end processing MAPK signaling pathway - yeast AU-rich element binding protein domain specific binding cytoplasmic exosome (RNase complex) nuclear exosome (RNase complex) RNA degradation Transcription_related, Transcription factor: HB | details |
| TreatCFM000208 | adenosine ribonucleotides de novo biosynthesis Golgi apparatus cell division site cell plate plant-type vacuole nuclear envelope cytokinesis by cell plate formation nucleic acid binding O-acetyltransferase activity cell wall organization or biogenesis | details |
| TreatCFM000254 | Amyotrophic lateral sclerosis (ALS) Transcription_related, Transcription regulator: SWI/SNF-SWI3 mitochondrial outer membrane translocase complex spermine and spermidine degradation III histone H3-K4 methylation protein import into mitochondrial matrix protein channel activity | details |
| TreatCFM000413 | Mitophagy - animal clathrin vesicle coat Fatty acid metabolism Phenylpropanoid biosynthesis very long chain fatty acid biosynthesis I very long chain fatty acid biosynthesis II vesicle-mediated transport | details |
| TreatCFM000637 | Amyotrophic lateral sclerosis (ALS) mitochondrial outer membrane translocase complex protein import into mitochondrial matrix vacuolar transport NLS-bearing protein import into nucleus base-excision repair DNA N-glycosylase activity nucleoplasm nuclear pore Base excision repair Lysosome regulation of catalytic activity nuclear localization sequence binding protein channel activity cysteine-type endopeptidase activity protein transporter activity Endocytosis | details |
| TreatCFM001018 | Cellular senescence cellulose catabolic process regulation of transcription, DNA-templated ATP-dependent peptidase activity cellulase activity adhesion to carbohydrates, Carbohydrate-Binding Modules: CBM57 hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc Transcription_related, Transcription factor: B3 multicellular organism development Transcription_related, Transcription factor: ERF | details |
| TreatCFM001020 | long-chain fatty acid-CoA ligase activity FAD binding clathrin vesicle coat Fatty acid metabolism Transcription_related, Transcription factor: HB long-chain fatty acid metabolic process cutin biosynthesis fatty acid β-oxidation II (peroxisome) long-chain fatty acid activation oleate biosynthesis I (plants) palmitate biosynthesis II (bacteria and plants) phosphatidylcholine acyl editing sporopollenin precursors biosynthesis stearate biosynthesis II (bacteria and plants) suberin monomers biosynthesis | details |
| TreatCFM001021 | integral component of endoplasmic reticulum membrane integral component of Golgi membrane Transcription_related, Transcription regulator: PHD 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity 3'-phospho-5'-adenylyl sulfate transmembrane transport FAD binding carbohydrate transport secondary metabolite biosynthetic process | details |
| TreatCFM001161 | Transcription_related, Transcription regulator: LIM glycolysis I (from glucose 6-phosphate) Transcription_related, Transcription factor: C2H2 | details |
| TreatCFM001242 | DNA replication, synthesis of RNA primer primosome complex DNA primase activity Cell cycle 4 iron, 4 sulfur cluster binding | details |
| TreatCFM001292 | Transcription_related, Transcription regulator: SWI/SNF-SWI3 spermine and spermidine degradation III starch biosynthesis regulation of SNARE complex assembly lysosome organization histone H3-K4 methylation endosome organization glycogen biosynthetic process transcription from RNA polymerase III promoter vesicle docking involved in exocytosis clathrin vesicle coat HOPS complex protein binding, bridging glucose-1-phosphate adenylyltransferase activity starch biosynthetic process DNA-directed RNA polymerase III complex RNA polymerase III activity ribonucleoside binding ATP-dependent peptidase activity DNA binding Autophagy - yeast | details |
| TreatCFM001378 | protein import into nucleus, docking protein import into nucleus, translocation cellular response to nitrogen starvation ribosomal protein import into nucleus Mismatch repair clathrin vesicle coat mismatch repair complex NLS-bearing protein import into nucleus autophagy nuclear membrane nuclear periphery Transcription_related, Transcription factor: MYB Apelin signaling pathway Phenylpropanoid biosynthesis very long chain fatty acid biosynthesis I very long chain fatty acid biosynthesis II Fatty acid metabolism Ran GTPase binding nuclear localization sequence binding mismatched DNA binding | details |
| TreatCFM001380 | Fanconi anemia pathway Pyrimidine metabolism pollen exine formation pyrimidine nucleotide biosynthetic process 'de novo' pyrimidine nucleobase biosynthetic process nucleotide phosphorylation CMP phosphorylation pyrimidine deoxyribonucleotide phosphorylation UTP and CTP de novo biosynthesis cytidylate kinase activity uridylate kinase activity adhesion to carbohydrates, Carbohydrate-Binding Modules: CBM57 hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc adenosine ribonucleotides de novo biosynthesis pyrimidine ribonucleotides interconversion | details |
| TreatCFM001381 | vacuolar transport Arachidonic acid metabolism Fanconi anemia pathway Endocytosis | details |
| TreatCFM001410 | polyamine transmembrane transport mitotic spindle assembly checkpoint Transcription_related, Transcription factor: bZIP cellular metabolic process amino acid transmembrane transport L-amino acid transmembrane transporter activity polyamine transmembrane transporter activity Cell cycle | details |
| TreatCFM001465 | proteolysis response to reactive oxygen species regulation of gene expression methylated histone binding AMPK signaling pathway Cell cycle - Caulobacter translational elongation Transcription_related, Transcription regulator: TRAF Ubiquitin_Proteasome_system, E3 adaptor: BTB ATP-dependent peptidase activity translation elongation factor activity | details |
| TreatCFM001596 | chlorophyll cycle chlorophyll synthetase activity Porphyrin and chlorophyll metabolism chlorophyll biosynthetic process clathrin vesicle coat vesicle-mediated transport transferase activity, transferring glycosyl groups | details |
| TreatCFM001801 | positive regulation of transport RNA binding protein binding involved in protein folding Ribosome biogenesis in eukaryotes tRNA processing rRNA processing unfolded protein binding | details |
| TreatCFM001901 | Ubiquitin_Proteasome_system, E3 adaptor: DDB1 DNA replication proofreading nucleotide-excision repair, DNA gap filling base-excision repair, gap-filling Mitophagy - animal clathrin vesicle coat delta DNA polymerase complex nucleotide-excision repair red, far-red light phototransduction 3'-5'-exodeoxyribonuclease activity Phenylpropanoid biosynthesis cullin-RING ubiquitin ligase complex DNA biosynthetic process DNA-directed DNA polymerase activity damaged DNA binding coenzyme binding proteasome-mediated ubiquitin-dependent protein catabolic process nucleic acid phosphodiester bond hydrolysis vesicle-mediated transport | details |
| TreatCFM002029 | Transcription_related, Transcription regulator: TRAF Ubiquitin_Proteasome_system, E3 adaptor: BTB Plant hormone signal transduction Spliceosome | details |
Expression profiles
 Show details about module gene expression profiling |