TreatCFM001212's detailed annotation
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Protein: Yellow color--query protein Green color--interaction proteins. Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
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Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontolog |
|---|---|---|
| glucokinase activity | 5.03E-06 | GO:0004340 |
| mannokinase activity | 5.03E-06 | GO:0019158 |
| glucose binding | 5.03E-06 | GO:0005536 |
| cellular glucose homeostasis | 1.12E-05 | GO:0001678 |
| glucose 6-phosphate metabolic process | 1.12E-05 | GO:0051156 |
| fructokinase activity | 1.40E-05 | GO:0008865 |
| carbohydrate phosphorylation | 8.17E-05 | GO:0046835 |
| glycolytic process | 0.000186115 | GO:0006096 |
| Protein_kinases_phosphatases, PPC:1.15.3: Leucine Rich Repeat Kinase IV | 0.001181649 | kinase family |
| carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity | 0.004168426 | GO:0004088 |
| Carbon metabolism | 0.00523805 | KEGG pathway |
| carbamoyl-phosphate synthase complex | 0.005397871 | GO:0005951 |
| urea cycle | 0.006165544 | plantCyc |
| L-arginine biosynthesis I (via L-ornithine) | 0.009261253 | plantCyc |
| UMP biosynthesis I | 0.009261253 | plantCyc |
| 'de novo' pyrimidine nucleobase biosynthetic process | 0.00941471 | GO:0006207 |
| L-arginine biosynthesis II (acetyl cycle) | 0.009718282 | plantCyc |
| ornithine-citrulline shuttle | 0.009718282 | plantCyc |
| L-glutamine degradation I | 0.009830926 | plantCyc |
| arginine biosynthetic process | 0.011546055 | GO:0006526 |
| glutamine metabolic process | 0.011546055 | GO:0006541 |
| Pyrimidine metabolism | 0.012368879 | KEGG pathway |
| cytosol | 0.045248963 | GO:0005829 |
Module member annotation
| Gene ID | Ortholog in Arabidopsis (Blast E-value) | Annotation in Arabidopsis |
|---|---|---|
| CRO_T002312 | AT5G25070 (2.00E-96) | unknown protein |
| CRO_T009633 | AT3G11210 (4.00E-83) | SGNH hydrolase-type esterase superfamily protein |
| CRO_T011462 | AT2G19860 (9.00E-137) | ATHXK2|HEXOKINASE 2 |
| CRO_T012302 | AT1G80640 (1.00E-19) | Protein kinase superfamily protein |
| CRO_T015106 | AT1G24909 (7.00E-11) | Glutamine amidotransferase type 1 family protein |
| CRO_T017816 | AT1G50460 (5.00E-51) | HKL1|hexokinase-like 1 |
| CRO_T024207 | AT1G15240 (2.00E-51) | Phox-associated domain; Phox-like; Sorting nexin, C-terminal |
| CRO_T033281 | AT3G47590 (1.00E-88) | alpha/beta-Hydrolases superfamily protein |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TreatCFM000194 | carbamoyl-phosphate synthase complex L-arginine biosynthesis I (via L-ornithine) UMP biosynthesis I urea cycle L-arginine biosynthesis II (acetyl cycle) ornithine-citrulline shuttle L-glutamine degradation I positive regulation of translational termination positive regulation of translational elongation translational frameshifting ion binding glucuronosyltransferase activity carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity histidine phosphotransfer kinase activity xylem development xylan biosynthetic process cytokinin-activated signaling pathway protein histidine kinase binding 'de novo' pyrimidine nucleobase biosynthetic process arginine biosynthetic process plant-type secondary cell wall biogenesis glutamine metabolic process Pyrimidine metabolism formation of glycosidic bonds, GlycosylTransferases: GTnc ribosome binding Transcription_related, Transcription factor: ERF translation elongation factor activity phosphorelay signal transduction system translational initiation Plant hormone signal transduction | details |
| TreatCFM000271 | Transcription_related, Transcription regulator: SOH1 L-alanine degradation II (to D-lactate) L-glutamate degradation I Cell cycle - yeast plant-type vacuole membrane glutamate dehydrogenase [NAD(P)+] activity cellular potassium ion homeostasis regulation of protein kinase activity Cell cycle | details |
| TreatCFM000297 | formation of glycosidic bonds, GlycosylTransferases: GTnc alpha-1,4-glucan synthase activity starch synthase activity amylopectin biosynthetic process glycogen (starch) synthase activity | details |
| TreatCFM001147 | carbamoyl-phosphate synthase complex chloroplast stroma L-arginine biosynthesis I (via L-ornithine) UMP biosynthesis I urea cycle L-arginine biosynthesis II (acetyl cycle) ornithine-citrulline shuttle L-glutamine degradation I cytokinin metabolic process 'de novo' pyrimidine nucleobase biosynthetic process plastid organization translational termination peptidyl-tyrosine dephosphorylation glutamine metabolic process arginine biosynthetic process carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity cytokinin dehydrogenase activity translation release factor activity, codon specific Inositol phosphate metabolism Pyrimidine metabolism Zeatin biosynthesis ribosome binding protein tyrosine phosphatase activity oxidoreductase activity, acting on CH-OH group of donors RNA processing | details |
| TreatCFM001213 | Protein_kinases_phosphatases, PPC:3.1.1: Casein Kinase I Family rRNA (cytosine-N4-)-methyltransferase activity mannokinase activity ATPase binding glucokinase activity glucose binding regulation of barrier septum assembly folic acid-containing compound metabolic process fructokinase activity cellular glucose homeostasis photosystem II repair photosystem II assembly chloroplast fission glucose 6-phosphate metabolic process rRNA base methylation Wnt signaling pathway fatty acid elongation -- saturated octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast) stearate biosynthesis II (bacteria and plants) regulation of cell shape carbohydrate phosphorylation oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Endocytosis palmitate biosynthesis II (bacteria and plants) glycolytic process | details |
| TreatCFM001251 | Ubiquitin_Proteasome_system, DUB: OTU glycerol-3-phosphate shuttle L-arginine biosynthesis I (via L-ornithine) UMP biosynthesis I urea cycle carbamoyl-phosphate synthase complex L-arginine biosynthesis II (acetyl cycle) ornithine-citrulline shuttle L-glutamine degradation I positive regulation of translational elongation translational frameshifting positive regulation of translational termination pyridoxal phosphate biosynthetic process glycerol-3-phosphate catabolic process cell morphogenesis carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity ion binding glycerol-3-phosphate dehydrogenase [NAD+] activity pyridoxamine-phosphate oxidase activity 'de novo' pyrimidine nucleobase biosynthetic process glycerol-3-phosphate dehydrogenase complex glutamine metabolic process arginine biosynthetic process Glycerophospholipid metabolism Pyrimidine metabolism ribosome binding FMN binding translation elongation factor activity translational initiation | details |
| TreatCFM001294 | phosphatidylinositol binding regulation of barrier septum assembly hypoxanthine salvage inosine biosynthetic process adenosine catabolic process histidinol dehydrogenase activity flavin-linked sulfhydryl oxidase activity regulation of ruffle assembly Ubiquitin_Proteasome_system, E3: HECT Transcription_related, Transcription regulator: mTERF ATPase binding adenosine deaminase activity detoxification of reactive carbonyls in chloroplasts L-histidine biosynthesis traumatin and (Z)-3-hexen-1-yl acetate biosynthesis protein metabolic process chloroplast fission histidine biosynthetic process endosome organization trichome branching protein histidine kinase binding | details |
| TreatCFM001516 | Protein_kinases_phosphatases, PPC:4.5.7: Unknown Function Kinase translational frameshifting positive regulation of translational termination positive regulation of translational elongation carbamoyl-phosphate synthase complex Pyrimidine metabolism cytochrome b6f complex assembly urea cycle L-arginine biosynthesis I (via L-ornithine) UMP biosynthesis I L-arginine biosynthesis II (acetyl cycle) ornithine-citrulline shuttle L-glutamine degradation I Protein_kinases_phosphatases, PPC:1.6.2: Plant External Response Like Kinase 'de novo' pyrimidine nucleobase biosynthetic process protein serine/threonine/tyrosine kinase activity carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity arginine biosynthetic process protein phosphorylation glutamine metabolic process protein serine/threonine kinase activity ribosome binding translation elongation factor activity translational initiation translation initiation factor activity | details |
| TreatCFM001537 | nuclear part Protein_kinases_phosphatases, PPC:1.15.3: Leucine Rich Repeat Kinase IV fatty acid biosynthesis initiation I octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast) intracellular ribonucleoprotein complex RNA secondary structure unwinding RNA processing Transcription_related, Transcription factor: NAC | details |
| TreatCFM001572 | Protein_kinases_phosphatases, PPC:3.1.1: Casein Kinase I Family carbamoyl-phosphate synthase complex glucokinase activity glucose binding mannokinase activity carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity L-arginine biosynthesis I (via L-ornithine) UMP biosynthesis I urea cycle L-arginine biosynthesis II (acetyl cycle) ornithine-citrulline shuttle L-glutamine degradation I fructokinase activity glucose 6-phosphate metabolic process cellular glucose homeostasis glutamine metabolic process 'de novo' pyrimidine nucleobase biosynthetic process arginine biosynthetic process regulation of cell shape Wnt signaling pathway carbohydrate phosphorylation Endocytosis Pyrimidine metabolism glycolytic process peptidyl-serine phosphorylation | details |
| TreatCFM001587 | carbamoyl-phosphate synthase complex glycerol-3-phosphate shuttle L-arginine biosynthesis I (via L-ornithine) UMP biosynthesis I urea cycle glycerol-3-phosphate catabolic process translational frameshifting positive regulation of translational termination cytochrome b6f complex assembly positive regulation of translational elongation L-arginine biosynthesis II (acetyl cycle) ornithine-citrulline shuttle L-glutamine degradation I Protein_kinases_phosphatases, PPC:1.6.2: Plant External Response Like Kinase glycerol-3-phosphate dehydrogenase complex 'de novo' pyrimidine nucleobase biosynthetic process arginine biosynthetic process glutamine metabolic process Glycerophospholipid metabolism Pyrimidine metabolism carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity glycerol-3-phosphate dehydrogenase [NAD+] activity translational initiation ribosome binding translation elongation factor activity | details |
| TreatCFM001650 | rRNA (cytosine-N4-)-methyltransferase activity thiamine-phosphate diphosphorylase activity phosphomethylpyrimidine kinase activity 4-amino-2-methyl-5-diphosphomethylpyrimidine biosynthesis hydroxymethylpyrimidine salvage thiamine diphosphate biosynthesis IV (eukaryotes) Thiamine metabolism thiamine biosynthetic process rRNA base methylation membrane Ubiquitin_Proteasome_system, E3 adaptor: DWD | details |
| TreatCFM001866 | photosystem II assembly gene expression photosystem II repair cellular nitrogen compound metabolic process cellular macromolecule metabolic process chloroplast thylakoid lumen mRNA surveillance pathway primary metabolic process | details |
| TreatCFM001928 | Protein_kinases_phosphatases, PPC:1.15.3: Leucine Rich Repeat Kinase IV carbamoyl-phosphate synthase complex Pyrimidine metabolism L-arginine biosynthesis I (via L-ornithine) UMP biosynthesis I urea cycle L-arginine biosynthesis II (acetyl cycle) ornithine-citrulline shuttle L-glutamine degradation I glutamine metabolic process arginine biosynthetic process 'de novo' pyrimidine nucleobase biosynthetic process carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity RNA secondary structure unwinding | details |
Expression profiles
 Show details about module gene expression profiling |