TreatCFM002143's detailed annotation
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Protein: Yellow color--query protein Green color--interaction proteins. Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
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Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontolog |
|---|---|---|
| cytosol | 0.006046195 | GO:0005829 |
| Sec61 translocon complex | 0.007709321 | GO:0005784 |
| aldose 1-epimerase activity | 0.007878474 | GO:0004034 |
| intracellular transport | 0.012030516 | GO:0046907 |
| hexose metabolic process | 0.012030516 | GO:0019318 |
| positive regulation of G2/M transition of mitotic cell cycle | 0.012030516 | GO:0010971 |
| cullin deneddylation | 0.012030516 | GO:0010388 |
| COP9 signalosome | 0.013698374 | GO:0008180 |
| membrane coat | 0.014122065 | GO:0030117 |
| Thyroid hormone signaling pathway | 0.01575043 | KEGG pathway |
| proteasome complex | 0.017449176 | GO:0000502 |
| Transcription_related, Transcription factor: MYB | 0.021315665 | TF family |
| Glycolysis / Gluconeogenesis | 0.023528126 | KEGG pathway |
| Lysosome | 0.023528126 | KEGG pathway |
| Protein export | 0.023528126 | KEGG pathway |
| protein transporter activity | 0.049981766 | GO:0008565 |
Module member annotation
| Gene ID | Ortholog in Arabidopsis (Blast E-value) | Annotation in Arabidopsis |
|---|---|---|
| CRO_T012042 | AT3G60540 (2.00E-15) | Preprotein translocase Sec, Sec61-beta subunit protein |
| CRO_T014942 | AT3G17940 (4.00E-146) | Galactose mutarotase-like superfamily protein |
| CRO_T015565 | AT3G52250 (3.00E-07) | Duplicated homeodomain-like superfamily protein |
| CRO_T019425 | AT2G24390 (9.00E-46) | AIG2-like (avirulence induced gene) family protein |
| CRO_T023134 | AT5G42970 (4.00E-104) | COP14|CONSTITUTIVE PHOTOMORPHOGENIC 14; COP8|CONSTITUTIVE PHOTOMORPHOGENIC 8; CSN4|COP9 SIGNALOSOME SUBUNIT 4; EMB134|EMBRYO DEFECTIVE 134; FUS4|FUSCA 4; FUS8|FUSCA 8 |
| CRO_T024567 | AT2G18180 (1.00E-16) | Sec14p-like phosphatidylinositol transfer family protein |
| CRO_T025650 | - | - |
| CRO_T026071 | AT3G09300 (0) | ORP3B|OSBP(oxysterol binding protein)-related protein 3B |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TreatCFM001000 | recycling endosome Thyroid hormone signaling pathway Rab guanyl-nucleotide exchange factor activity formation of glycosidic bonds, GlycosylTransferases: GTnc Ubiquitin_Proteasome_system, E2: UBC Transcription_related, Transcription factor: MYB ubiquitin protein ligase binding cell wall organization positive regulation of GTPase activity protein ubiquitination transferase activity, transferring glycosyl groups ubiquitin protein ligase activity Golgi membrane | details |
| TreatCFM001246 | TNF signaling pathway NF-kappa B signaling pathway Cytochrome_P450, Cytochrome P450: CYP71B hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc Protein_kinases_phosphatases, PPC:1.11.1: Legume Lectin Domain Kinase ethylene biosynthesis I (plants) Flavonoid biosynthesis flavonoid biosynthesis (in equisetum) flavonol biosynthesis gibberellin biosynthesis I (non C-3, non C-13 hydroxylation) gibberellin biosynthesis III (early C-13 hydroxylation) leucodelphinidin biosynthesis pinobanksin biosynthesis syringetin biosynthesis vindoline and vinblastine biosynthesis formation of glycosidic bonds, GlycosylTransferases: GTnc | details |
| TreatCFM001289 | histone methyltransferase activity (H3-K9 specific) methyl-CpNpN binding steroid dehydrogenase activity methyl-CpNpG binding alcohol dehydrogenase (NADP+) activity NADP+ binding double-stranded methylated DNA binding oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen methyl-CpG binding monooxygenase activity endopeptidase activity enzyme regulator activity Cytochrome_P450, Cytochrome P450: CYP714A response to toxic substance maintenance of DNA methylation histone H3-K9 methylation response to absence of light regulation of protein catabolic process response to red light intracellular transport response to far red light positive regulation of G2/M transition of mitotic cell cycle cullin deneddylation proteasome storage granule Sec61 translocon complex | details |
| TreatCFM001367 | superpathway of thiamine diphosphate biosynthesis III (eukaryotes) thiazole biosynthesis III (eukaryotes) rRNA base methylation thiazole biosynthetic process cellular response to DNA damage stimulus UDP-glucose metabolic process thiamine biosynthetic process tRNA methyltransferase activity UTP:glucose-1-phosphate uridylyltransferase activity UDP-glucose biosynthesis Thiamine metabolism rRNA methyltransferase activity stachyose degradation sucrose biosynthesis II tRNA methylation iron-sulfur cluster binding Pentose and glucuronate interconversions response to stress thylakoid cytoplasm cytosol stromule Protein_kinases_phosphatases, PPC:1.2.2: Receptor Like Cytoplasmic Kinase VII protein homodimerization activity | details |
| TreatCFM001369 | regulation of cellular metabolic process cullin deneddylation positive regulation of G2/M transition of mitotic cell cycle carbohydrate metabolic process Transcription_related, Transcription factor: C3H glyoxylate cycle TCA cycle II (plants and fungi) malate metabolic process phosphotransferase activity, alcohol group as acceptor L-malate dehydrogenase activity Sec61 translocon complex gluconeogenesis I tricarboxylic acid cycle COP9 signalosome Protein export proteasome complex | details |
| TreatCFM001393 | carbohydrate binding glucan 1,3-alpha-glucosidase activity aldose 1-epimerase activity L-amino acid transmembrane transporter activity solute:proton antiporter activity negative regulation of biological process L-alpha-amino acid transmembrane transport hexose metabolic process L-amino acid transport MicroRNAs in cancer early endosome membrane potassium ion transport Glycolysis / Gluconeogenesis N-Glycan biosynthesis SNARE binding SNAP receptor activity cellular macromolecule metabolic process antiporter activity primary metabolic process exocytosis vesicle fusion | details |
| TreatCFM001395 | MicroRNAs in cancer L-amino acid transmembrane transporter activity antiporter activity integral component of plasma membrane L-amino acid transport L-alpha-amino acid transmembrane transport hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc amino acid transmembrane transport hydrolase activity, acting on ester bonds | details |
| TreatCFM001396 | MicroRNAs in cancer L-amino acid transport L-alpha-amino acid transmembrane transport L-amino acid transmembrane transporter activity response to stress antiporter activity | details |
| TreatCFM001449 | recycling endosome mannitol degradation II Thyroid hormone signaling pathway Rab guanyl-nucleotide exchange factor activity sinapyl alcohol dehydrogenase activity cinnamyl-alcohol dehydrogenase activity Protein_kinases_phosphatases, PPC:4.2.1: Calcium Dependent Protein Kinase Transcription_related, Transcription regulator: PHD calcium-dependent protein serine/threonine kinase activity zinc ion binding calmodulin-dependent protein kinase activity actin binding Phenylpropanoid biosynthesis regulation of stomatal movement actin filament organization peptidyl-serine phosphorylation protein autophosphorylation positive regulation of GTPase activity abscisic acid-activated signaling pathway calmodulin binding Transcription_related, Transcription factor: MYB | details |
| TreatCFM001783 | Protein_kinases_phosphatases, PPC:4.5.8: Unknown Function Kinase Thyroid hormone signaling pathway Protein_kinases_phosphatases, PPC:4.2.1: Calcium Dependent Protein Kinase Transcription_related, Transcription factor: MYB regulation of stomatal movement actin filament organization calcium-dependent protein serine/threonine kinase activity actin binding calmodulin-dependent protein kinase activity | details |
| TreatCFM001821 | mRNA splicing, via spliceosome Spliceosome Transcription_related, Transcription factor: Whirly MicroRNAs in cancer hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc DNA replication factor A complex L-amino acid transport L-alpha-amino acid transmembrane transport Ubiquitin_Proteasome_system, DUB: USP Prp19 complex Cul4-RING E3 ubiquitin ligase complex COPII vesicle coat Proteasome precatalytic spliceosome catalytic step 2 spliceosome defense response to fungus regulation of gene expression RNA secondary structure unwinding ER to Golgi vesicle-mediated transport cellular protein metabolic process positive regulation of transcription, DNA-templated | details |
| TreatCFM001892 | Transcription_related, Transcription factor: NF-X1 Human papillomavirus infection Thyroid hormone signaling pathway response to light intensity salicylic acid biosynthetic process hexose metabolic process response to microbial phytotoxin regulation of hydrogen peroxide metabolic process regulation of stomatal movement Glycolysis / Gluconeogenesis actin filament organization aldose 1-epimerase activity Transcription_related, Transcription factor: MYB response to salt stress defense response to bacterium | details |
| TreatCFM001962 | L-alpha-amino acid transmembrane transport L-amino acid transport hexose metabolic process MicroRNAs in cancer Thyroid hormone signaling pathway Glycolysis / Gluconeogenesis aldose 1-epimerase activity early endosome membrane L-amino acid transmembrane transporter activity Transcription_related, Transcription factor: MYB vesicle fusion exocytosis protein transport SNAP receptor activity SNARE binding antiporter activity carbohydrate binding | details |
| TreatCFM002120 | vesicle-mediated transport endopeptidase activity enzyme regulator activity regulation of protein catabolic process intracellular transport proteasome storage granule proteasome regulatory particle, base subcomplex membrane coat Transcription_related, Transcription factor: bHLH Autophagy - yeast Lysosome Proteasome regulation of catalytic activity protein transport proteasome-mediated ubiquitin-dependent protein catabolic process endomembrane system cellular process | details |
Expression profiles
 Show details about module gene expression profiling |