TreatCFM001369's detailed annotation
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Protein: Yellow color--query protein Green color--interaction proteins. Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
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Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontolog |
|---|---|---|
| regulation of cellular metabolic process | 0.01027378 | GO:0031323 |
| cullin deneddylation | 0.01027378 | GO:0010388 |
| positive regulation of G2/M transition of mitotic cell cycle | 0.01027378 | GO:0010971 |
| carbohydrate metabolic process | 0.01027378 | GO:0005975 |
| Transcription_related, Transcription factor: C3H | 0.011995624 | TF family |
| glyoxylate cycle | 0.015567144 | plantCyc |
| TCA cycle II (plants and fungi) | 0.015567144 | plantCyc |
| malate metabolic process | 0.018473688 | GO:0006108 |
| phosphotransferase activity, alcohol group as acceptor | 0.019095408 | GO:0016773 |
| L-malate dehydrogenase activity | 0.019095408 | GO:0030060 |
| Sec61 translocon complex | 0.020770369 | GO:0005784 |
| gluconeogenesis I | 0.021562991 | plantCyc |
| tricarboxylic acid cycle | 0.026477545 | GO:0006099 |
| COP9 signalosome | 0.027679505 | GO:0008180 |
| Protein export | 0.033880502 | KEGG pathway |
| proteasome complex | 0.039176148 | GO:0000502 |
Module member annotation
| Gene ID | Ortholog in Arabidopsis (Blast E-value) | Annotation in Arabidopsis |
|---|---|---|
| CRO_T002055 | AT2G22780 (6.00E-29) | PMDH1|peroxisomal NAD-malate dehydrogenase 1 |
| CRO_T012042 | AT3G60540 (2.00E-15) | Preprotein translocase Sec, Sec61-beta subunit protein |
| CRO_T013906 | - | - |
| CRO_T019425 | AT2G24390 (9.00E-46) | AIG2-like (avirulence induced gene) family protein |
| CRO_T021915 | AT5G51130 (3.00E-77) | S-adenosyl-L-methionine-dependent methyltransferases superfamily protein |
| CRO_T023134 | AT5G42970 (4.00E-104) | COP14|CONSTITUTIVE PHOTOMORPHOGENIC 14; COP8|CONSTITUTIVE PHOTOMORPHOGENIC 8; CSN4|COP9 SIGNALOSOME SUBUNIT 4; EMB134|EMBRYO DEFECTIVE 134; FUS4|FUSCA 4; FUS8|FUSCA 8 |
| CRO_T025728 | AT4G30310 (7.00E-94) | FGGY family of carbohydrate kinase |
| CRO_T033609 | AT1G01630 (2.00E-18) | Sec14p-like phosphatidylinositol transfer family protein |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TreatCFM000019 | details | |
| TreatCFM000035 | details | |
| TreatCFM000226 | inosine-5'-phosphate biosynthesis II phosphoribosylaminoimidazole carboxylase activity phosphoribosylaminoimidazolesuccinocarboxamide synthase activity Transcription_related, Transcription factor: LOB adenine biosynthetic process 'de novo' IMP biosynthetic process | details |
| TreatCFM000359 | Cytochrome_P450, Cytochrome P450: CYP71B | details |
| TreatCFM000360 | radial pattern formation bundle sheath cell fate specification regulation of cellular metabolic process maintenance of protein location in nucleus asymmetric cell division gravitropism glyoxylate cycle TCA cycle II (plants and fungi) Transcription_related, Transcription factor: GRAS gluconeogenesis I malate metabolic process leaf development tricarboxylic acid cycle L-malate dehydrogenase activity | details |
| TreatCFM001246 | TNF signaling pathway NF-kappa B signaling pathway Cytochrome_P450, Cytochrome P450: CYP71B hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc Protein_kinases_phosphatases, PPC:1.11.1: Legume Lectin Domain Kinase ethylene biosynthesis I (plants) Flavonoid biosynthesis flavonoid biosynthesis (in equisetum) flavonol biosynthesis gibberellin biosynthesis I (non C-3, non C-13 hydroxylation) gibberellin biosynthesis III (early C-13 hydroxylation) leucodelphinidin biosynthesis pinobanksin biosynthesis syringetin biosynthesis vindoline and vinblastine biosynthesis formation of glycosidic bonds, GlycosylTransferases: GTnc | details |
| TreatCFM001289 | histone methyltransferase activity (H3-K9 specific) methyl-CpNpN binding steroid dehydrogenase activity methyl-CpNpG binding alcohol dehydrogenase (NADP+) activity NADP+ binding double-stranded methylated DNA binding oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen methyl-CpG binding monooxygenase activity endopeptidase activity enzyme regulator activity Cytochrome_P450, Cytochrome P450: CYP714A response to toxic substance maintenance of DNA methylation histone H3-K9 methylation response to absence of light regulation of protein catabolic process response to red light intracellular transport response to far red light positive regulation of G2/M transition of mitotic cell cycle cullin deneddylation proteasome storage granule Sec61 translocon complex | details |
| TreatCFM001368 | Protein_kinases_phosphatases, PPC:4.5.6: LAMMER Kinase Family L-methionine salvage cycle II (plants) ethylene biosynthesis I (plants) mitochondrial inner membrane presequence translocase complex Transcription_related, Transcription factor: C3H protein import into mitochondrial matrix mRNA processing protein autophosphorylation biosynthetic process protein serine/threonine/tyrosine kinase activity transaminase activity | details |
| TreatCFM001395 | MicroRNAs in cancer L-amino acid transmembrane transporter activity antiporter activity integral component of plasma membrane L-amino acid transport L-alpha-amino acid transmembrane transport hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc amino acid transmembrane transport hydrolase activity, acting on ester bonds | details |
| TreatCFM001779 | developmental process involved in reproduction detection of nutrient organ senescence vegetative phase change regulation of cellular metabolic process L-malate dehydrogenase activity protein tyrosine kinase activity glyoxylate cycle TCA cycle II (plants and fungi) sugar mediated signaling pathway Apelin signaling pathway primary root development gluconeogenesis I malate metabolic process tricarboxylic acid cycle zinc ion binding peptidyl-tyrosine phosphorylation abscisic acid-activated signaling pathway | details |
| TreatCFM001791 | condensed chromosome outer kinetochore spindle microtubule chromosome segregation cell division vesicle fusion exocytosis SNARE complex SNARE binding SNAP receptor activity microtubule binding transporter activity | details |
| TreatCFM001821 | mRNA splicing, via spliceosome Spliceosome Transcription_related, Transcription factor: Whirly MicroRNAs in cancer hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc DNA replication factor A complex L-amino acid transport L-alpha-amino acid transmembrane transport Ubiquitin_Proteasome_system, DUB: USP Prp19 complex Cul4-RING E3 ubiquitin ligase complex COPII vesicle coat Proteasome precatalytic spliceosome catalytic step 2 spliceosome defense response to fungus regulation of gene expression RNA secondary structure unwinding ER to Golgi vesicle-mediated transport cellular protein metabolic process positive regulation of transcription, DNA-templated | details |
| TreatCFM002143 | cytosol Sec61 translocon complex aldose 1-epimerase activity intracellular transport hexose metabolic process positive regulation of G2/M transition of mitotic cell cycle cullin deneddylation COP9 signalosome membrane coat Thyroid hormone signaling pathway proteasome complex Transcription_related, Transcription factor: MYB Glycolysis / Gluconeogenesis Lysosome Protein export protein transporter activity | details |
| TreatCFM002159 | vacuolar membrane cell tip growth regulation of signal transduction potassium ion transmembrane transporter activity potassium ion transmembrane transport protein processing response to salt stress | details |
Expression profiles
 Show details about module gene expression profiling |