TissueCFM000115's detailed annotation
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Protein: Yellow color--query protein Green color--interaction proteins. Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
| This network produced by cytoscapeweb |
Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontolog |
|---|---|---|
| ent-kaurene biosynthesis I | 0.00283357 | plantCyc |
| multi-organism process | 0.01181422 | GO:0051704 |
| metabolic process | 0.017681062 | GO:0008152 |
| arginine biosynthetic process | 0.017681062 | GO:0006526 |
| 2-Oxocarboxylic acid metabolism | 0.022191485 | KEGG pathway |
| Diterpenoid biosynthesis | 0.022191485 | KEGG pathway |
| root development | 0.027174327 | GO:0048364 |
| Transcription_related, Transcription factor: bHLH | 0.028351986 | TF family |
| terpene synthase activity | 0.039005747 | GO:0010333 |
| N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity | 0.039005747 | GO:0003992 |
Module member annotation
| Gene ID | Ortholog in Arabidopsis (Blast E-value) | Annotation in Arabidopsis |
|---|---|---|
| CRO_T003357 | AT5G10570 (1.00E-24) | basic helix-loop-helix (bHLH) DNA-binding superfamily protein |
| CRO_T004969 | - | - |
| CRO_T009836 | AT1G79460 (0) | ATKS|ENT-KAURENE SYNTHASE; ATKS1|ENT-KAURENE SYNTHASE 1; GA2|GA REQUIRING 2 |
| CRO_T012598 | - | - |
| CRO_T013296 | - | - |
| CRO_T015213 | - | - |
| CRO_T016443 | AT1G80600 (8.00E-33) | TUP5|TUMOR PRONE 5; WIN1|HOPW1-1-interacting 1 |
| CRO_T020277 | AT1G65520 (2.00E-35) | ATECI1|DELTA(3), DELTA(2)-ENOYL COA ISOMERASE 1; ECHIC|ENOYL-COA HYDRATASE/ISOMERASE C |
| CRO_T025035 | - | - |
| CRO_T025918 | - | - |
| CRO_T028937 | AT5G54310 (2.00E-15) | AGD5|ARF-GAP domain 5; NEV|NEVERSHED |
| CRO_T032043 | - | - |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TissueCFM000012 | ent-kaurene biosynthesis I Diterpenoid biosynthesis | details |
| TissueCFM000019 | Transcription_related, Transcription factor: bHLH | details |
| TissueCFM000022 | details | |
| TissueCFM000047 | post-embryonic root development Human papillomavirus infection MAPK signaling pathway - yeast Pyruvate metabolism | details |
| TissueCFM000054 | ent-kaurene biosynthesis I DNA-directed DNA polymerase activity 3'-5' exonuclease activity | details |
| TissueCFM000059 | large ribosomal subunit chloroplast ent-kaurene biosynthesis I rRNA binding Ribosome Diterpenoid biosynthesis transferase activity translation structural constituent of ribosome small ribosomal subunit RNA methyltransferase activity terpene synthase activity RNA methylation RNA processing | details |
| TissueCFM000071 | UDP-D-apiose biosynthesis (from UDP-D-glucuronate) UDP-D-xylose biosynthesis UDP-sugars interconversion UDP-glucuronate decarboxylase activity | details |
| TissueCFM000072 | details | |
| TissueCFM000099 | ent-kaurene biosynthesis I integral component of lumenal side of endoplasmic reticulum membrane Golgi-associated vesicle membrane integral component of cytoplasmic side of endoplasmic reticulum membrane lysosomal membrane aspartic endopeptidase activity, intramembrane cleaving Diterpenoid biosynthesis terpene synthase activity membrane protein proteolysis pollen germination signal peptide processing pollen development | details |
| TissueCFM000100 | ent-kaurene biosynthesis I | details |
| TissueCFM000114 | ent-kaurene biosynthesis I Diterpenoid biosynthesis terpene synthase activity Transcription_related, Transcription factor: bHLH | details |
| TissueCFM000127 | Transcription_related, Transcription factor: BBR-BPC integral component of lumenal side of endoplasmic reticulum membrane Golgi-associated vesicle membrane integral component of cytoplasmic side of endoplasmic reticulum membrane lysosomal membrane ribonucleoside-diphosphate reductase complex membrane protein proteolysis signal peptide processing pollen germination deoxyribonucleotide biosynthetic process aspartic endopeptidase activity, intramembrane cleaving ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor | details |
| TissueCFM000128 | Transcription_related, Transcription factor: HB | details |
| TissueCFM000129 | post-embryonic root development MAPK signaling pathway - yeast Propanoate metabolism protein domain specific binding Transcription_related, Transcription factor: FAR1 | details |
| TissueCFM000130 | vitamin E biosynthesis (tocopherols) | details |
| TissueCFM000142 | Fatty acid metabolism regulation of biological process response to bacterium fatty acid β-oxidation II (peroxisome) unsaturated, even numbered fatty acid β-oxidation very long chain fatty acid biosynthesis II Transcription_related, Transcription factor: bHLH Transcription_related, Transcription factor: HB | details |
| TissueCFM000151 | Fatty acid metabolism | details |
| TissueCFM000155 | ent-kaurene biosynthesis I | details |
| TissueCFM000159 | Cytochrome_P450, Cytochrome P450: CYP83B 4-hydroxy-tetrahydrodipicolinate synthase L-lysine biosynthesis VI salvigenin biosynthesis diaminopimelate biosynthetic process lysine biosynthetic process via diaminopimelate | details |
| TissueCFM000163 | Cytochrome_P450, Cytochrome P450: CYP81K | details |
| TissueCFM000169 | ent-kaurene biosynthesis I hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc | details |
| TissueCFM000170 | ent-kaurene biosynthesis I terpene synthase activity Diterpenoid biosynthesis Zeatin biosynthesis | details |
| TissueCFM000171 | oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor Transcription_related, Transcription factor: bHLH MAPK signaling pathway - plant | details |
| TissueCFM000180 | response to manganese ion response to copper ion manganese:proton antiporter activity late endosome response to zinc ion cellular manganese ion homeostasis manganese ion transmembrane transport regulation of sequestering of zinc ion anion transmembrane transport zinc II ion transmembrane transport Transcription_related, Transcription factor: bHLH zinc ion transmembrane transporter activity | details |
| TissueCFM000198 | ent-kaurene biosynthesis I Diterpenoid biosynthesis | details |
| TissueCFM000207 | costunolide biosynthesis Cytochrome_P450, Cytochrome P450: CYP71B benzoate biosynthesis I (CoA-dependent, β-oxidative) Transcription_related, Transcription factor: bHLH | details |
| TissueCFM000208 | Diterpenoid biosynthesis ent-kaurene biosynthesis I | details |
| TissueCFM000215 | Ubiquitin_Proteasome_system, DUB: ULP Transcription_related, Transcription factor: bHLH | details |
| TissueCFM000216 | ent-kaurene biosynthesis I Diterpenoid biosynthesis terpene synthase activity | details |
| TissueCFM000232 | Transcription_related, Transcription factor: bHLH | details |
| TissueCFM000263 | response to hypoxia ent-kaurene biosynthesis I Taurine and hypotaurine metabolism aerobic respiration I (cytochrome c) aerobic respiration III (alternative oxidase pathway) NAD/NADH phosphorylation and dephosphorylation | details |
| TissueCFM000271 | carboxypeptidase activity histone H3-K36 methylation histone H3-K4 methylation negative regulation of flower development | details |
| TissueCFM000280 | ent-kaurene biosynthesis I Diterpenoid biosynthesis terpene synthase activity Transcription_related, Transcription factor: bHLH | details |
| TissueCFM000299 | Transcription_related, Transcription factor: bHLH | details |
| TissueCFM000328 | ajmaline and sarpagine biosynthesis Indole alkaloid biosynthesis methyl salicylate esterase activity guiding stereospecific synthesis activity dimethylallyltranstransferase activity lipase activity Terpenoid backbone biosynthesis Transcription_related, Transcription factor: bHLH isoprenoid biosynthetic process phenylpropanoid biosynthetic process systemic acquired resistance, salicylic acid mediated signaling pathway regulation of catalytic activity peptidase activity | details |
| TissueCFM000394 | ent-kaurene biosynthesis I Diterpenoid biosynthesis zinc ion transmembrane transporter activity terpene synthase activity zinc II ion transmembrane transport | details |
| TissueCFM000432 | response to biotic stimulus defense response benzoate biosynthesis I (CoA-dependent, β-oxidative) Transcription_related, Transcription factor: MYB-related Transcription_related, Transcription factor: bHLH | details |
| TissueCFM000434 | ent-kaurene biosynthesis I terpene synthase activity Diterpenoid biosynthesis Photosynthesis | details |
| TissueCFM000440 | post-embryonic root development DNA recombination MAPK signaling pathway - yeast protein domain specific binding | details |
| TissueCFM000445 | Mannose type O-glycan biosyntheis post-embryonic root development hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc MAPK signaling pathway - yeast | details |
| TissueCFM000454 | ent-kaurene biosynthesis I Diterpenoid biosynthesis terpene synthase activity Transcription_related, Transcription factor: bHLH | details |
| TissueCFM000462 | Transcription_related, Transcription factor: AP2 metabolic process ent-kaurene biosynthesis I Transcription_related, Transcription factor: PLATZ Diterpenoid biosynthesis single-organism process | details |
| TissueCFM000505 | ent-kaurene biosynthesis I hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc homogalacturonan degradation Diterpenoid biosynthesis terpene synthase activity polygalacturonase activity lyase activity Photosynthesis | details |
| TissueCFM000521 | ent-kaurene biosynthesis I Diterpenoid biosynthesis terpene synthase activity Transcription_related, Transcription factor: bHLH | details |
| TissueCFM000541 | ent-kaurene biosynthesis I Diterpenoid biosynthesis terpene synthase activity | details |
| TissueCFM000562 | details | |
| TissueCFM000592 | post-embryonic root development protein domain specific binding MAPK signaling pathway - yeast MAPK signaling pathway - plant | details |
| TissueCFM000670 | Transcription_related, Transcription factor: bHLH | details |
| TissueCFM000671 | Transcription_related, Transcription factor: bHLH | details |
| TissueCFM000672 | Diterpenoid biosynthesis ent-kaurene biosynthesis I phosphatidylinositol-3-phosphate binding phosphatidylinositol-3,5-bisphosphate binding adhesion to carbohydrates, Carbohydrate-Binding Modules: CBM57 hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc leaf senescence autophagic cell death protein lipidation nucleophagy protein localization to pre-autophagosomal structure mitophagy | details |
| TissueCFM000682 | Transcription_related, Transcription factor: bHLH aspartyl esterase activity pectinesterase activity pectinesterase inhibitor activity negative regulation of catalytic activity pectin catabolic process cell wall modification Pentose and glucuronate interconversions cell wall | details |
| TissueCFM000700 | ent-kaurene biosynthesis I | details |
| TissueCFM000710 | ent-kaurene biosynthesis I Diterpenoid biosynthesis terpene synthase activity | details |
| TissueCFM000713 | ent-kaurene biosynthesis I Diterpenoid biosynthesis terpene synthase activity | details |
| TissueCFM000773 | ent-kaurene biosynthesis I Diterpenoid biosynthesis terpene synthase activity | details |
| TissueCFM000781 | Transcription_related, Transcription factor: bHLH Transcription_related, Transcription factor: ERF | details |
| TissueCFM000798 | ent-kaurene biosynthesis I Diterpenoid biosynthesis terpene synthase activity | details |
| TissueCFM000799 | ent-kaurene biosynthesis I terpene synthase activity Diterpenoid biosynthesis Photosynthesis | details |
| TissueCFM000835 | Transcription_related, Transcription factor: bHLH | details |
| TissueCFM000875 | Transcription_related, Transcription factor: bHLH aspartyl esterase activity pectinesterase activity pectinesterase inhibitor activity negative regulation of catalytic activity pectin catabolic process cell wall modification Pentose and glucuronate interconversions cell wall | details |
| TissueCFM000880 | ent-kaurene biosynthesis I aerobic electron transport chain cytochrome-c oxidase activity terpene synthase activity Diterpenoid biosynthesis hydrogen ion transmembrane transport | details |
| TissueCFM000898 | manganese:proton antiporter activity response to copper ion response to manganese ion Cell cycle manganese ion transmembrane transport cellular manganese ion homeostasis mitotic sister chromatid cohesion response to zinc ion regulation of sequestering of zinc ion late endosome cohesin core heterodimer phenylpropanoid biosynthetic process Transcription_related, Transcription factor: bHLH zinc II ion transmembrane transport guiding stereospecific synthesis activity zinc ion transmembrane transporter activity chromatin binding regulation of catalytic activity DNA repair | details |
| TissueCFM000904 | Transcription_related, Transcription factor: bHLH Transcription_related, Transcription factor: MYB | details |
| TissueCFM000972 | Transcription_related, Transcription factor: bHLH | details |
| TissueCFM000977 | Cytochrome_P450, Cytochrome P450: CYP722A brassinosteroid homeostasis brassinosteroid biosynthetic process sterol metabolic process multicellular organism development Transcription_related, Transcription factor: bHLH | details |
| TissueCFM001086 | ABC transporters auxin influx transmembrane transporter activity taurine-transporting ATPase activity root hair elongation gravitropism amine transport basipetal auxin transport auxin efflux auxin influx xenobiotic transport auxin efflux transmembrane transporter activity xenobiotic-transporting ATPase activity Transcription_related, Transcription factor: MYB | details |
| TissueCFM001092 | ent-kaurene biosynthesis I Diterpenoid biosynthesis terpene synthase activity 3'-5' exonuclease activity DNA-directed DNA polymerase activity nucleic acid phosphodiester bond hydrolysis DNA biosynthetic process DNA replication | details |
| TissueCFM001171 | ent-kaurene biosynthesis I Diterpenoid biosynthesis terpene synthase activity | details |
| TissueCFM001174 | Transcription_related, Transcription factor: bHLH Cytochrome_P450, Cytochrome P450: CYP735A trans-zeatin biosynthesis Zeatin biosynthesis anion transmembrane transport potassium ion transmembrane transport secologanin synthase activity potassium ion transmembrane transporter activity | details |
| TissueCFM001197 | Stilbenoid, diarylheptanoid and gingerol biosynthesis D-arabinono-1,4-lactone oxidase activity L-gulonolactone oxidase activity aromatic compound biosynthetic process fatty acid metabolic process Transcription_related, Transcription factor: bHLH O-methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity flavin adenine dinucleotide binding | details |
| TissueCFM001283 | transport | details |
Expression profiles
 Show details about module gene expression profiling |