TreatCFM000715's detailed annotation
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Protein: Yellow color--query protein Green color--interaction proteins. Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
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Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontolog |
|---|---|---|
| Ubiquitin_Proteasome_system, DUB: JAMM | 6.59E-06 | ubs family |
| cullin deneddylation | 0.006378076 | GO:0010388 |
| COP9 signalosome | 0.006378076 | GO:0008180 |
| proteasome complex | 0.006769501 | GO:0000502 |
| Proteasome | 0.012169878 | KEGG pathway |
| proteasome-mediated ubiquitin-dependent protein catabolic process | 0.022590732 | GO:0043161 |
Module member annotation
| Gene ID | Ortholog in Arabidopsis (Blast E-value) | Annotation in Arabidopsis |
|---|---|---|
| CRO_T001807 | - | - |
| CRO_T005518 | - | - |
| CRO_T011731 | - | - |
| CRO_T012733 | AT4G26430 (7.00E-134) | CSN6B|COP9 signalosome subunit 6B |
| CRO_T016715 | - | - |
| CRO_T022263 | - | - |
| CRO_T024069 | - | - |
| CRO_T033225 | AT3G11270 (4.00E-157) | MEE34|maternal effect embryo arrest 34 |
| CRO_T033811 | - | - |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TreatCFM000026 | Ubiquitin_Proteasome_system, DUB: JAMM Proteasome carbohydrate transport proteasome-mediated ubiquitin-dependent protein catabolic process proteasome complex | details |
| TreatCFM000031 | L-phenylalanine biosynthesis II L-phenylalanine biosynthesis III (cytosolic, plants) hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc cellular response to gravity L-phenylalanine biosynthetic process response to cadmium ion prephenate dehydratase activity arogenate dehydratase activity microtubule-based process tubulin complex Phagosome | details |
| TreatCFM000046 | details | |
| TreatCFM000065 | Cytochrome_P450, Cytochrome P450: CYP724A | details |
| TreatCFM000073 | cullin deneddylation COP9 signalosome Ubiquitin_Proteasome_system, DUB: JAMM Oxidative phosphorylation | details |
| TreatCFM000076 | Protein_kinases_phosphatases, PPC:4.1.4: MAP2K Ubiquitin_Proteasome_system, DUB: JAMM defense response, incompatible interaction histone modification activation of MAPK activity transcription elongation from RNA polymerase II promoter cullin deneddylation COP9 signalosome Cdc73/Paf1 complex MAP kinase kinase activity MAP kinase activity transcription coactivator activity transcription from RNA polymerase II promoter MAPK cascade MAPK signaling pathway - plant | details |
| TreatCFM000078 | proteasome complex Transcription_related, Transcription factor: GeBP Ubiquitin_Proteasome_system, DUB: JAMM Proteasome Transcription_related, Transcription factor: Trihelix proteasome-mediated ubiquitin-dependent protein catabolic process | details |
| TreatCFM000099 | Spliceosome sulfate activation for sulfonation sulfate reduction II (assimilatory) Transcription_related, Transcription factor: NAC Ubiquitin_Proteasome_system, DUB: JAMM HTLV-I infection L-valine degradation I | details |
| TreatCFM000118 | Ubiquitin_Proteasome_system, DUB: JAMM formation of glycosidic bonds, GlycosylTransferases: GTnc | details |
| TreatCFM000126 | Ubiquitin_Proteasome_system, DUB: JAMM proteasome complex Proteasome proteasome-mediated ubiquitin-dependent protein catabolic process | details |
| TreatCFM000182 | trans-zeatin biosynthesis | details |
| TreatCFM000183 | calcium ion transport Ubiquitin_Proteasome_system, DUB: JAMM Proteasome proteasome-mediated ubiquitin-dependent protein catabolic process proteasome complex | details |
| TreatCFM000207 | proteasome complex xylogalacturonan biosynthesis Ubiquitin_Proteasome_system, DUB: JAMM Proteasome formation of glycosidic bonds, GlycosylTransferases: GTnc proteasome-mediated ubiquitin-dependent protein catabolic process transferase activity | details |
| TreatCFM000214 | tubulin binding formation of glycosidic bonds, GlycosylTransferases: GTnc lipid IVA biosynthesis Lipopolysaccharide biosynthesis organophosphate metabolic process carbohydrate derivative metabolic process protein N-glycosylation (eukaryotic, high mannose) tubulin complex assembly cullin deneddylation | details |
| TreatCFM000233 | Ubiquitin_Proteasome_system, DUB: JAMM cullin deneddylation COP9 signalosome carbohydrate transport | details |
| TreatCFM000269 | intracellular COP9 signalosome Ubiquitin_Proteasome_system, DUB: JAMM cullin deneddylation GTP binding small GTPase mediated signal transduction intracellular protein transport | details |
| TreatCFM000272 | xyloglucan biosynthetic process endomembrane system organization cellular response to gravity fucose biosynthetic process | details |
| TreatCFM000279 | Ubiquitin_Proteasome_system, DUB: JAMM Golgi vesicle budding phospholipid translocation Proteasome phospholipid-translocating ATPase activity proteasome-mediated ubiquitin-dependent protein catabolic process proteasome complex | details |
| TreatCFM000284 | second spliceosomal transesterification activity generation of catalytic spliceosome for second transesterification step nuclear retention of unspliced pre-mRNA at the site of transcription Ubiquitin_Proteasome_system, DUB: JAMM U2-type post-spliceosomal complex U5 snRNP proteasome complex U4/U6 x U5 tri-snRNP complex proteasome-mediated ubiquitin-dependent protein catabolic process Proteasome Spliceosome | details |
| TreatCFM000285 | Ubiquitin_Proteasome_system, DUB: JAMM precatalytic spliceosome proteasome complex response to salt stress proteasome-mediated ubiquitin-dependent protein catabolic process Proteasome Spliceosome | details |
| TreatCFM000349 | benzoyl-CoA biosynthesis formation of glycosidic bonds, GlycosylTransferases: GTnc Transcription_related, Transcription factor: BES1 Transcription_related, Transcription regulator: LIM Ubiquitin_Proteasome_system, DUB: JAMM glycoprotein 2-beta-D-xylosyltransferase activity fatty acid β-oxidation II (peroxisome) transcription factor activity, sequence-specific DNA binding transcription regulatory region DNA binding benzoate biosynthesis I (CoA-dependent, β-oxidative) protein N-linked glycosylation formation of translation preinitiation complex regulation of transcription, DNA-templated carbohydrate transport regulation of translational initiation brassinosteroid mediated signaling pathway | details |
| TreatCFM000368 | COP9 signalosome cullin deneddylation Ubiquitin_Proteasome_system, DUB: JAMM | details |
| TreatCFM000390 | Ubiquitin_Proteasome_system, DUB: JAMM L-phenylalanine biosynthesis II L-phenylalanine biosynthesis III (cytosolic, plants) prephenate dehydratase activity arogenate dehydratase activity L-phenylalanine biosynthetic process oxalate metabolic process oxalate decarboxylase activity nutrient reservoir activity manganese ion binding carbohydrate transport amino acid binding proteasome-mediated ubiquitin-dependent protein catabolic process Proteasome Biosynthesis of amino acids | details |
| TreatCFM000403 | Ubiquitin_Proteasome_system, DUB: JAMM proteasome complex Proteasome proteasome-mediated ubiquitin-dependent protein catabolic process | details |
| TreatCFM000416 | Ubiquitin_Proteasome_system, DUB: JAMM proteasome complex Proteasome proteasome-mediated ubiquitin-dependent protein catabolic process | details |
| TreatCFM000423 | Ubiquitin_Proteasome_system, DUB: JAMM proteasome complex Proteasome nucleic acid metabolic process cellular macromolecule metabolic process proteasome-mediated ubiquitin-dependent protein catabolic process | details |
| TreatCFM000430 | Ubiquitin_Proteasome_system, DUB: JAMM Proteasome chloroplast accumulation movement proteasome complex microtubule proteasome-mediated ubiquitin-dependent protein catabolic process microtubule-based movement | details |
| TreatCFM000434 | ADP dimethylallyltransferase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds ATP dimethylallyltransferase activity | details |
| TreatCFM000442 | cullin deneddylation Ubiquitin_Proteasome_system, DUB: JAMM COP9 signalosome Phenylpropanoid biosynthesis intracellular part ATP-dependent helicase activity coenzyme binding | details |
| TreatCFM000453 | Ubiquitin_Proteasome_system, DUB: JAMM proteasome complex proteasome-mediated ubiquitin-dependent protein catabolic process Proteasome Sesquiterpenoid and triterpenoid biosynthesis | details |
| TreatCFM000510 | pyrimidine ribonucleosides salvage I cullin deneddylation pyrimidine nucleoside salvage pyrimidine nucleobase metabolic process DNA integration Ubiquitin_Proteasome_system, DUB: JAMM COP9 signalosome uridine kinase activity Transcription_related, Transcription factor: B3 | details |
| TreatCFM000574 | cullin deneddylation COP9 signalosome Ubiquitin_Proteasome_system, DUB: JAMM Transcription_related, Transcription factor: B3 Transcription_related, Transcription factor: WRKY | details |
| TreatCFM000600 | cullin deneddylation COP9 signalosome Ubiquitin_Proteasome_system, DUB: JAMM | details |
| TreatCFM000601 | cullin deneddylation COP9 signalosome Ubiquitin_Proteasome_system, DUB: JAMM | details |
| TreatCFM000607 | cullin deneddylation COP9 signalosome Ubiquitin_Proteasome_system, DUB: JAMM | details |
| TreatCFM000608 | COP9 signalosome Ubiquitin_Proteasome_system, DUB: JAMM cullin deneddylation DNA integration | details |
| TreatCFM000612 | Ubiquitin_Proteasome_system, DUB: JAMM Proteasome proteasome complex proteasome-mediated ubiquitin-dependent protein catabolic process | details |
| TreatCFM000613 | Ubiquitin_Proteasome_system, DUB: JAMM proteasome complex precatalytic spliceosome COP9 signalosome cullin deneddylation proteasome-mediated ubiquitin-dependent protein catabolic process response to salt stress Proteasome | details |
| TreatCFM000630 | Ubiquitin_Proteasome_system, DUB: JAMM cullin deneddylation COP9 signalosome small GTPase mediated signal transduction GTP binding | details |
| TreatCFM000631 | COP9 signalosome Ubiquitin_Proteasome_system, DUB: JAMM cullin deneddylation DNA integration | details |
| TreatCFM000686 | integral component of plasma membrane Smc5-Smc6 complex Ubiquitin_Proteasome_system, DUB: JAMM Proteasome proteasome complex cellular water homeostasis calcium ion transmembrane transport single-organism transport resolution of recombination intermediates double-strand break repair via homologous recombination ion transmembrane transport water channel activity calcium-transporting ATPase activity glycerol channel activity Transcription_related, Transcription factor: bHLH proteasome-mediated ubiquitin-dependent protein catabolic process calmodulin binding | details |
| TreatCFM000741 | proteasome complex Ubiquitin_Proteasome_system, DUB: JAMM Proteasome proteasome-mediated ubiquitin-dependent protein catabolic process Transcription_related, Transcription factor: ERF | details |
| TreatCFM000774 | COP9 signalosome cullin deneddylation Ubiquitin_Proteasome_system, DUB: JAMM | details |
| TreatCFM000799 | Ubiquitin_Proteasome_system, DUB: JAMM Proteasome proteasome complex proteasome-mediated ubiquitin-dependent protein catabolic process intracellular part | details |
| TreatCFM000829 | Ubiquitin_Proteasome_system, DUB: JAMM cullin deneddylation COP9 signalosome carbohydrate transport | details |
| TreatCFM000843 | Ubiquitin_Proteasome_system, DUB: JAMM negative regulation of innate immune response petal formation negative regulation of cell proliferation mRNA polyadenylation leaf development proteasome complex mRNA surveillance pathway Proteasome polynucleotide adenylyltransferase activity proteasome-mediated ubiquitin-dependent protein catabolic process | details |
| TreatCFM000859 | coenzyme A biosynthesis I Ubiquitin_Proteasome_system, DUB: JAMM cullin deneddylation COP9 signalosome small ribosomal subunit | details |
| TreatCFM000869 | fucosyltransferase activity Various types of N-glycan biosynthesis formation of glycosidic bonds, GlycosylTransferases: GTnc Lewis a epitope biosynthetic process fucosylation Ubiquitin_Proteasome_system, DUB: JAMM COP9 signalosome Golgi cisterna membrane cullin deneddylation protein glycosylation | details |
| TreatCFM000870 | COP9 signalosome cullin deneddylation Ubiquitin_Proteasome_system, DUB: JAMM ubiquitin-protein transferase activity Ubiquitin_Proteasome_system, E3: U-box protein ubiquitination | details |
| TreatCFM000876 | cullin deneddylation COP9 signalosome Ubiquitin_Proteasome_system, DUB: JAMM | details |
| TreatCFM000923 | cullin deneddylation COP9 signalosome Ubiquitin_Proteasome_system, DUB: JAMM | details |
| TreatCFM000964 | cullin deneddylation COP9 signalosome Ubiquitin_Proteasome_system, DUB: JAMM Phenylpropanoid biosynthesis coenzyme binding | details |
| TreatCFM000978 | proteasome complex Ubiquitin_Proteasome_system, DUB: JAMM Proteasome Transcription_related, Transcription regulator: PHD proteasome-mediated ubiquitin-dependent protein catabolic process | details |
| TreatCFM000980 | proteasome complex RNA-dependent DNA biosynthetic process RNA-directed DNA polymerase activity Ubiquitin_Proteasome_system, DUB: JAMM Proteasome DNA integration DNA recombination Transcription_related, Transcription factor: bHLH proteasome-mediated ubiquitin-dependent protein catabolic process | details |
| TreatCFM000981 | Ubiquitin_Proteasome_system, DUB: JAMM Proteasome proteasome complex intracellular part response to stimulus regulation of catalytic activity regulation of cellular process proteasome-mediated ubiquitin-dependent protein catabolic process | details |
| TreatCFM001067 | cullin deneddylation COP9 signalosome Ubiquitin_Proteasome_system, DUB: JAMM | details |
| TreatCFM001069 | cullin deneddylation COP9 signalosome Ubiquitin_Proteasome_system, DUB: JAMM Transcription_related, Transcription factor: B3 catalytic activity | details |
| TreatCFM001084 | cullin deneddylation COP9 signalosome Ubiquitin_Proteasome_system, DUB: JAMM | details |
| TreatCFM001102 | cullin deneddylation COP9 signalosome Ubiquitin_Proteasome_system, DUB: JAMM | details |
| TreatCFM001204 | 1,3-β-D-glucan biosynthesis Ubiquitin_Proteasome_system, DUB: JAMM COP9 signalosome spliceosomal complex 1,3-beta-D-glucan synthase complex ubiquitin ligase complex positive regulation of proteasomal ubiquitin-dependent protein catabolic process cullin deneddylation (1->3)-beta-D-glucan biosynthetic process ubiquitin conjugating enzyme binding 1,3-beta-D-glucan synthase activity | details |
| TreatCFM001206 | Ubiquitin_Proteasome_system, DUB: JAMM cullin deneddylation COP9 signalosome nitrogen compound metabolic process hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds Phenylpropanoid biosynthesis plastid coenzyme binding transferase activity, transferring acyl groups | details |
| TreatCFM001221 | Ubiquitin_Proteasome_system, DUB: JAMM cullin deneddylation COP9 signalosome carbohydrate transport | details |
| TreatCFM001254 | cullin deneddylation COP9 signalosome Ubiquitin_Proteasome_system, DUB: JAMM | details |
| TreatCFM001329 | cullin deneddylation COP9 signalosome Ubiquitin_Proteasome_system, DUB: JAMM | details |
| TreatCFM001390 | riboflavin synthase activity Ubiquitin_Proteasome_system, DUB: JAMM proteasome complex Riboflavin metabolism Transcription_related, Transcription factor: bZIP Proteasome riboflavin biosynthetic process proteasome-mediated ubiquitin-dependent protein catabolic process | details |
| TreatCFM001637 | Ubiquitin_Proteasome_system, DUB: JAMM rosmarinic acid biosynthesis I rosmarinic acid biosynthesis II 4-hydroxybenzoate biosynthesis I (eukaryotes) rRNA primary transcript binding oligosaccharyltransferase complex COP9 signalosome maturation of LSU-rRNA maturation of 5.8S rRNA protein N-linked glycosylation cullin deneddylation oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor ribosomal large subunit assembly NAD binding preribosome, large subunit precursor N-Glycan biosynthesis embryo development ending in seed dormancy | details |
| TreatCFM001704 | Ubiquitin_Proteasome_system, DUB: JAMM hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds RNA polymerase II transcription factor activity, sequence-specific DNA binding cullin deneddylation ribosomal large subunit assembly nitrogen compound metabolic process COP9 signalosome nucleoplasm transferase activity, transferring acyl groups | details |
| TreatCFM001804 | Ubiquitin_Proteasome_system, DUB: JAMM Transcription_related, Transcription regulator: LIM formation of translation preinitiation complex regulation of translational initiation eukaryotic 48S preinitiation complex eukaryotic translation initiation factor 3 complex proteasome complex eukaryotic 43S preinitiation complex proteasome-mediated ubiquitin-dependent protein catabolic process Homologous recombination Proteasome RNA transport | details |
Expression profiles
 Show details about module gene expression profiling |