TreatCFM001465's detailed annotation
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Protein: Yellow color--query protein Green color--interaction proteins. Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
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Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontolog |
|---|---|---|
| proteolysis | 0.005169714 | GO:0006508 |
| response to reactive oxygen species | 0.005169714 | GO:0000302 |
| regulation of gene expression | 0.010901268 | GO:0010468 |
| methylated histone binding | 0.011262632 | GO:0035064 |
| AMPK signaling pathway | 0.013059677 | KEGG pathway |
| Cell cycle - Caulobacter | 0.013059677 | KEGG pathway |
| translational elongation | 0.013754163 | GO:0006414 |
| Transcription_related, Transcription regulator: TRAF | 0.017046448 | TF family |
| Ubiquitin_Proteasome_system, E3 adaptor: BTB | 0.032831092 | ubs family |
| ATP-dependent peptidase activity | 0.043675045 | GO:0004176 |
| translation elongation factor activity | 0.043675045 | GO:0003746 |
Module member annotation
| Gene ID | Ortholog in Arabidopsis (Blast E-value) | Annotation in Arabidopsis |
|---|---|---|
| CRO_T000771 | AT2G25740 (3.00E-158) | ATP-dependent protease La (LON) domain protein |
| CRO_T001489 | AT3G24010 (2.00E-25) | ATING1|INHIBITOR OF GROWTH 1 |
| CRO_T005861 | AT1G64280 (9.00E-157) | ATNPR1|ARABIDOPSIS NONEXPRESSER OF PR GENES 1; NIM1|NON-INDUCIBLE IMMUNITY 1; NPR1|NONEXPRESSER OF PR GENES 1; SAI1|SALICYLIC ACID INSENSITIVE 1 |
| CRO_T009211 | - | - |
| CRO_T016268 | AT5G08650 (1.00E-16) | Small GTP-binding protein |
| CRO_T016536 | AT5G48830 (8.00E-99) | unknown protein |
| CRO_T021644 | AT4G17040 (1.00E-106) | CLPR4|CLP protease R subunit 4; HON5|happy on norflurazon 5 |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TreatCFM000254 | Amyotrophic lateral sclerosis (ALS) Transcription_related, Transcription regulator: SWI/SNF-SWI3 mitochondrial outer membrane translocase complex spermine and spermidine degradation III histone H3-K4 methylation protein import into mitochondrial matrix protein channel activity | details |
| TreatCFM001018 | Cellular senescence cellulose catabolic process regulation of transcription, DNA-templated ATP-dependent peptidase activity cellulase activity adhesion to carbohydrates, Carbohydrate-Binding Modules: CBM57 hydrolysis and/or rearrangement of glycosidic bonds, Glycoside Hydrolases: GHnc Transcription_related, Transcription factor: B3 multicellular organism development Transcription_related, Transcription factor: ERF | details |
| TreatCFM001292 | Transcription_related, Transcription regulator: SWI/SNF-SWI3 spermine and spermidine degradation III starch biosynthesis regulation of SNARE complex assembly lysosome organization histone H3-K4 methylation endosome organization glycogen biosynthetic process transcription from RNA polymerase III promoter vesicle docking involved in exocytosis clathrin vesicle coat HOPS complex protein binding, bridging glucose-1-phosphate adenylyltransferase activity starch biosynthetic process DNA-directed RNA polymerase III complex RNA polymerase III activity ribonucleoside binding ATP-dependent peptidase activity DNA binding Autophagy - yeast | details |
| TreatCFM001378 | protein import into nucleus, docking protein import into nucleus, translocation cellular response to nitrogen starvation ribosomal protein import into nucleus Mismatch repair clathrin vesicle coat mismatch repair complex NLS-bearing protein import into nucleus autophagy nuclear membrane nuclear periphery Transcription_related, Transcription factor: MYB Apelin signaling pathway Phenylpropanoid biosynthesis very long chain fatty acid biosynthesis I very long chain fatty acid biosynthesis II Fatty acid metabolism Ran GTPase binding nuclear localization sequence binding mismatched DNA binding | details |
| TreatCFM001801 | positive regulation of transport RNA binding protein binding involved in protein folding Ribosome biogenesis in eukaryotes tRNA processing rRNA processing unfolded protein binding | details |
| TreatCFM001888 | 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity 3'-phospho-5'-adenylyl sulfate transmembrane transport Transcription_related, Transcription regulator: TRAF integral component of Golgi membrane clathrin vesicle coat integral component of endoplasmic reticulum membrane ATP-dependent peptidase activity Ubiquitin_Proteasome_system, E3 adaptor: BTB carbohydrate transport Plant hormone signal transduction vesicle-mediated transport endomembrane system | details |
| TreatCFM002029 | Transcription_related, Transcription regulator: TRAF Ubiquitin_Proteasome_system, E3 adaptor: BTB Plant hormone signal transduction Spliceosome | details |
| TreatCFM002122 | proteolysis serine-type endopeptidase activity gamma-glutamyl-peptidase activity folate polyglutamylation II glutamate removal from folates glutathione peroxidase activity tetrahydrofolylpolyglutamate metabolic process protein-lysine N-methyltransferase activity glutathione-peroxide redox reactions reactive oxygen species degradation Arachidonic acid metabolism Cell cycle - Caulobacter Folate biosynthesis response to reactive oxygen species Transcription_related, Transcription regulator: PHD Transcription_related, Transcription regulator: SET peptidyl-lysine monomethylation glutamine metabolic process regulation of gene expression | details |
| TreatCFM002131 | glutathione-peroxide redox reactions reactive oxygen species degradation Arachidonic acid metabolism Cell cycle - yeast AMPK signaling pathway glutathione peroxidase activity Transcription_related, Transcription factor: NAC translation elongation factor activity GTPase activity cellular oxidant detoxification response to oxidative stress translational elongation cellular process | details |
| TreatCFM002134 | Cell cycle - Caulobacter UDP-D-galacturonate biosynthesis II (from D-galacturonate) serine-type endopeptidase activity phosphate acquisition Golgi medial cisterna cis-Golgi network response to reactive oxygen species microtubule organizing center organization microtubule nucleation regulation of vesicle targeting, to, from or within Golgi proteolysis spindle assembly cytokinesis by cell plate formation mitotic nuclear division regulation of gene expression peptidyl-tyrosine dephosphorylation intra-Golgi vesicle-mediated transport phosphotransferase activity, alcohol group as acceptor SNARE interactions in vesicular transport protein tyrosine phosphatase activity SNARE binding SNAP receptor activity vesicle fusion Amino sugar and nucleotide sugar metabolism ER to Golgi vesicle-mediated transport | details |
| TreatCFM002149 | Cell cycle - Caulobacter serine-type endopeptidase activity proteolysis response to reactive oxygen species Transcription_related, Transcription regulator: SET peptidyl-lysine monomethylation regulation of gene expression DNA recombination ATP-dependent helicase activity protein-lysine N-methyltransferase activity RNA degradation | details |
| TreatCFM002154 | Cell cycle - Caulobacter serine-type endopeptidase activity ADP binding protein-lysine N-methyltransferase activity proteolysis response to reactive oxygen species Transcription_related, Transcription regulator: SET peptidyl-lysine monomethylation regulation of gene expression Plant-pathogen interaction defense response | details |
| TreatCFM002164 | methylated histone binding Cell cycle - Caulobacter MAPK signaling pathway peptidyl-lysine monomethylation response to reactive oxygen species regulation of gene expression protein-lysine N-methyltransferase activity Transcription_related, Transcription regulator: SET | details |
Expression profiles
 Show details about module gene expression profiling |